On the front cover this weeks is the work of Chi-Ming Che and colleagues from The University of Hong Kong, who present a gold(I)/chiral Brønsted acid cooperative catalytic system for the efficient one-pot asymmetric synthesis of tetrahydroquinolines, with one or two chiral centres at different positions as well as highly divergent functional groups, from reaction of 2-aminobenzaldehydes or 2-aminophenones with alkynes.
Highly regio-, diastereo- and enantioselective one-pot gold/chiral Brønsted acid-catalysed cascade synthesis of bioactive diversely substituted tetrahydroquinolines
Xin-Yuan Liu, Ya-Ping Xiao, Fung-Ming Siu, Li-Chen Ni, Yong Chen, Lin Wang and Chi-Ming Che
The inside cover highlights the work of Prasat Kittakoop et al. on the isolation, characterization, and biological activities of a novel tricyclic polyketide, 2 of its biosynthetic congeners as well as austdiol, a known azaphilone, from the endophytic fungus Dothideomycete sp., which was isolated from the Thai medicinal plant, Tiliacora triandra.
A novel tricyclic polyketide and its biosynthetic precursor azaphilone derivatives from the endophytic fungus Dothideomycete sp
Sarath P. D. Senadeera, Suthep Wiyakrutta, Chulabhorn Mahidol, Somsak Ruchirawat and Prasat Kittakoop
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