10 of the best: Natural Products in Organic & Biomolecular Chemistry

In the latest blog of our series celebrating OBC’s 10th anniversary we bring you a selection of 10 of our most highly cited articles in the area of natural products. Every single one will be free to access for you to enjoy for the next week.

Triggering cryptic natural product biosynthesis in microorganisms
Kirstin Scherlach and Christian Hertweck
DOI: 10.1039/B821578B

Chemistry and biology of wortmannin
Peter Wipf and Robert J. Halter
DOI: 10.1039/B504418A

[3 + 3] Cycloadditions and related strategies in alkaloid natural product synthesis

Joseph P. A. Harrity and Olivier Provoost
DOI: 10.1039/B502349C

Discovery and optimization of non-steroidal FXR agonists from natural product-like libraries

K. C. Nicolaou, Ronald M. Evans, A. J. Roecker, Robert Hughes, Michael Downes and Jeffery A. Pfefferkorn
DOI: 10.1039/B300525A

Golden opportunities in natural product synthesis: first total synthesis of (−)-isocyclocapitelline and (−)-isochrysotricine by gold-catalyzed allene cycloisomerization

Frank Volz and Norbert Krause
DOI: 10.1039/B703995F

Asymmetric synthesis of N,O,O,O-tetra-acetyl D-lyxo-phytosphingosine, jaspine B (pachastrissamine), 2-epi-jaspine B, and deoxoprosophylline via lithium amide conjugate addition
Elin Abraham, E. Anne Brock, José I. Candela-Lena, Stephen G. Davies, Matthew Georgiou, Rebecca L. Nicholson, James H. Perkins, Paul M. Roberts, Angela J. Russell, Elena M. Sánchez-Fernández, Philip M. Scott, Andrew D. Smith and James E. Thomson
DOI: 10.1039/B801671B

Concise synthesis of (±)-horsfiline and (±)-coerulescine by tandem cyclisation of iodoaryl alkenyl azides
Dimitrios E. Lizos and John A. Murphy
DOI: 10.1039/B208114H

Chemical and biomimetic total syntheses of natural and engineered MCoTI cyclotides
Panumart Thongyoo, Núria Roqué-Rosell, Robin J. Leatherbarrow and Edward W. Tate
DOI: 10.1039/B801667D

Total synthesis of (±)-rhazinal, an alkaloidal spindle toxin from Kopsia teoi
Martin G. Banwell, Alison J. Edwards, Katrina A. Jolliffe, Jason A. Smith, Ernest Hamel and Pascal Verdier-Pinard
DOI: 10.1039/B209992F

Enantioselective synthesis of (+)(R)- and (−)(S)-nicotine based on Ir-catalysed allylic amination
Carolin Welter, Rosa M. Moreno, Stephane Streiff and Günter Helmchen
DOI: 10.1039/B508634E

Missed our other 10th anniversary posts? Take a look here for some of our top cited work, including 10 of the best catalysis articles and 10 of the best medicinal chemistry articles.

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One Response to “10 of the best: Natural Products in Organic & Biomolecular Chemistry”

  1. […] Also of interest is the Natural Products themed issue from MedChemComm, and this OBC blog featuring 10 of the best, most highly cited papers covering natural products from the past 10 […]

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