OBC issue 16 has landed!

The outside front cover of this week’s OBC is a communication from Barbara Zajcand colleagues at The City College and The City University of New York presenting a mild and efficient synthesis of 1-aryl-1-fluoroethenes from benzothiazolyl (aryl)fluoromethyl sulfones and paraformaldehyde, under DBU- or Cs2CO3-mediated conditions at room temperature.

Expedient synthesis of α-substituted fluoroethenes
Samir K. Mandal, Arun K. Ghosh, Rakesh Kumar and Barbara Zajc
Org. Biomol. Chem., 2012, 10, 3164–3167
DOI: 10.1039/C2OB07031F

The inside front cover is work from Keisuke Kato et al. at Toho University on the cyclization–carbonylation–cyclization coupling reaction of γ-propynyl-1,3-diketones catalysed by palladium(II)-bisoxazoline complexes to give symmetrical ketones bearing two oxabicyclic groups in moderate to excellent yields.

Cyclization–carbonylation–cyclization coupling reaction of γ-propynyl-1,3-diketones with palladium(II)-bisoxazoline catalyst
Taichi Kusakabe, Yasuko Kawai, Rong Shen, Tomoyuki Mochida and Keisuke Kato
Org. Biomol. Chem., 2012, 10, 3192–3194
DOI: 10.1039/C2OB07016B

  

Also in this issue:

Review:

Recent advances and applications of iridium-catalysed asymmetric allylic substitution by Paolo Tosatti and co-workers

Hot articles:

Electrophilicity of α-oxo gold carbene intermediates: halogen abstractions from halogenated solvents leading to the formation of chloro/bromomethyl ketones
Weimin He, Longyong Xie, Yingying Xu, Jiannan Xiang and Liming Zhang

Highly enantioselective [4 + 2] cycloadditions of allenoates and dual activated olefins catalyzed by N-acyl aminophosphines
Hua Xiao, Zhuo Chai, Dongdong Cao, Hongyu Wang, Jinghao Chen and Gang Zhao

Enantioselective synthesis of fluorene derivatives by chiral N-triflyl phosphoramide catalyzed double Friedel–Crafts alkylation reaction
Shou-Guo Wang, Long Han, Mi Zeng,  Feng-Lai Sun, Wei Zhang and Shu-Li You

Hydrogen tunnelling influences the isomerisation of some small radicals of interstellar importance. A theoretical investigation
Tianfang Wang and John H. Bowie

See the rest HERE….

Digg This
Reddit This
Stumble Now!
Share on Facebook
Bookmark this on Delicious
Share on LinkedIn
Bookmark this on Technorati
Post on Twitter
Google Buzz (aka. Google Reader)

Leave a Reply