Collagen triple helices and click chemisry on the cover of OBC issue 10

Welcome to OBC issue 10!

OBC‘s cover this week features work by Helma Wennemers et al. at the University of Basel (Switzerland), who have used click chemistry to introduce moieties as sterically demanding as monosaccharides into the Yaa position of collagen model peptides, and studied the effect of different triazolyl derivatives as well as the configuration of the functionalized proline residue on the thermal stability of the collagen triple helices.

Conformational stability of collagen triple helices functionalized in the Yaa position by click chemistry

Roman S. Erdmann and Helma Wennemers
Org. Biomol. Chem., 2012, 10, 1982-1986
DOI: 10.1039/C2OB06720J

As with all of our cover articles, it will be FREE to access for the next 6 weeks

This article is part of OBC‘s web-themed issue on Foldamer Chemistry – View the full collection of articles here

The issue also contains:

three ‘Hot Articles’

and that’s just a taster… we hope you enjoy the whole issue!

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