Glyco-hydantoin conjugate synthesis and mimicking GFP to improve fluorophores on the cover of Issue 24

On the front cover of our last 2011 issue is work from Alessandro Volonterio and colleagues developing a multi-component one-pot synthetic route to novel glyco-hydantoin conjugates, which may be used as synthons for glyco-pseudopeptides.

Three-component, one-pot sequential synthesis of glyco-hydantoin conjugates
Maria Cristina Bellucci, Alessandra Ghilardi and Alessandro Volonterio
DOI: 10.1039/C1OB06312J

On the inside front cover is work from Stefan Matile and colleagues, applying principles from green and red fluorescent proteins from jellyfish and corals to develop the properties of core-substituted naphthalenediimide and perylenediimide fluorophores. Some these newly synthesized fluorophores are able to cover all primary colours upon pH changes, and as such may find practical use in naked-eye sensing arrays.

Naphthalene- and perylenediimides with hydroquinones, catechols, boronic esters and imines in the core
Andrea Fin, Irina Petkova, David Alonso Doval, Naomi Sakai, Eric Vauthey and Stefan Matile
DOI: 10.1039/C1OB05702B

View the rest of Issue 24 here

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