HOT: indolizinones investigated

Alison R. Hardin Narayan and Richmond Sarpong have investigated the fundamental reactivity of indolizinones, relatively unexplored 6,5-N-fused bicycles.  They find that these bicycles have excellent ability to transfer stereochemistry  from the ring fusion position to other stereocenters, as well as readily undergoing Diels-Alder cycloadditions and selective hydrogenation, among other reactions.

To read more on the potential applications of indolizinones download the article now – it’s free to access for the next four weeks:

Indolizinones as synthetic scaffolds: fundamental reactivity and the relay of stereochemical information
Alison R. Hardin Narayan and Richmond Sarpong
DOI: 10.1039/C1OB06423A

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