On the cover of Issue 14 is work from Dario Pasini and colleagues at the University of Pavia. They have designed a new route to the synthetically challenging cyclophane, [2.2]cyclophanediene. By using a Pummerer rearrangement of the [3.3]dithiacyclophane starting material, followed by sulfur extrusion the group were able to demonstrate the applicability of this mild and high yielding route.
For the full details download the article – it’s free to access for 6 weeks:
Mild preparation of functionalized [2.2]paracyclophanes via the Pummerer rearrangement
Matteo Montanari, Alberto Bugana, Arvind K. Sharma and Dario Pasini
Org. Biomol. Chem., 2011, 9, 5018-5020
DOI: 10.1039/C1OB05319A
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