Natural Products in OBC

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although signing up to OBC’s e-alert (free service) means you will receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

First total synthesis of (+)-broussonetine W: glycosidase inhibition of natural product & analogs
Ying-Ying Song, Kyoko Kinami, Atsushi Kato, Yue-Mei Jia, Yi-Xian Li, George W. J. Fleet and Chu-Yi Yu
DOI: 10.1039/C6OB00720A, Paper


Synthesis of a simplified triazole analogue of pateamine A
A. Hemi Cumming, Sarah L. Brown, Xu Tao, Claire Cuyamendous, Jessica J. Field, John H. Miller, Joanne E. Harvey and Paul H. Teesdale-Spittle
DOI: 10.1039/C6OB00086J, Paper


Studies towards the synthesis of tedanolide C. Construction of the C13-epi C1–C15 fragment
Joana Zambrana, Pedro Romea and Fèlix Urpí
DOI: 10.1039/C6OB00896H, Communication


Asymmetric synthesis of crambescin A–C carboxylic acids and their inhibitory activity on voltage-gated sodium channels
Atsuo Nakazaki, Yoshiki Nakane, Yuki Ishikawa, Mari Yotsu-Yamashita and Toshio Nishikawa
DOI: 10.1039/C6OB00914J, Paper


Nitropyrrole natural products: isolation, biosynthesis and total synthesis
Xiao-Bo Ding, Margaret A. Brimble and Daniel P. Furkert
DOI: 10.1039/C5OB02599K, Review Article


Some chemical speculation on the biosynthesis of corallidictyals A–D
Adrian W. Markwell-Heys and Jonathan H. George
DOI: 10.1039/C6OB00171H, Communication


First total synthesis of trehalose containing tetrasaccharides from Mycobacterium smegmatis
Manishkumar A. Chaube, Vikram A. Sarpe, Santanu Jana and Suvarn S. Kulkarni
DOI: 10.1039/C6OB00412A, Communication


Towards theory driven structure elucidation of complex natural products: mandelalides and coibamide A
Kevin M. Snyder, Justyna Sikorska, Tao Ye, Lijing Fang, Wu Su, Rich G. Carter, Kerry L. McPhail and Paul H.-Y. Cheong
DOI: 10.1039/C6OB00707D, Paper


Total synthesis of desoxycyclomarin C and the cyclomarazines A and B
Philipp Barbie and Uli Kazmaier
DOI: 10.1039/C6OB00801A, Paper


Total synthesis of cyclomarins A, C and D, marine cyclic peptides with interesting anti-tuberculosis and anti-malaria activities
Philipp Barbie and Uli Kazmaier
DOI: 10.1039/C6OB00800C, Paper


Total synthesis, biosynthesis and biological profiles of clavine alkaloids
Stephanie R. McCabe and Peter Wipf
DOI:10.1039/C6OB00878J, Review Article


Recent applications in natural product synthesis of dihydrofuran and -pyran formation by ring-closing alkene metathesis
Reece Jacques, Ritashree Pal, Nicholas A. Parker, Claire E. Sear, Peter W. Smith, Aubert Ribaucourt and David M. Hodgson
DOI:10.1039/C6OB00593D, Review Article


We hope you enjoy this selection!
Why not submit your latest natural product research to OBC today?

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Natural Products in OBC

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although signing up to OBC’s e-alert (free service) means you will receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

Abietane diterpenoids from Caryopteris incana (Thunb.) Miq.
Sen-Miao Zhao, Gui-Xin Chou, Qing-Shan Yang, Wei Wang and Jian-Li Zhou
DOI: 10.1039/C6OB00139D, Paper


Multicomponent access to indolo[3,3a-c]isoquinolin-3,6-diones: formal synthesis of (±)-plicamine
Marco V. Mijangos and Luis D. Miranda
DOI: 10.1039/C6OB00231E, Communication


A surprising switch in absolute configuration of anti-inflammatory macrolactones
Johannes Tauber, Markus Rohr, Thorsten Walter, Dieter Schollmeyer, Karin Rahn-Hotze, Gerhard Erkel and Till Opatz
DOI: 10.1039/C6OB00430J, Communication


The total synthesis and functional evaluation of fourteen stereoisomers of yaku’amide B. The importance of stereochemistry for hydrophobicity and cytotoxicity
Hiroyuki Mutoh, Yusuke Sesoko, Takefumi Kuranaga, Hiroaki Itoh and Masayuki Inoue
DOI: 10.1039/C6OB00640J, Communication


Epimerization of C5 of an N-hydroxypyrrolidine in the synthesis of swainsonine related iminosugars
Bao-Chen Qian, Akiko Kamori, Kyoko Kinami, Atsushi Kato, Yi-Xian Li, George W. J. Fleet and Chu-Yi Yu
DOI: 10.1039/C6OB00531D, Paper


Total chemical synthesis of lassomycin and lassomycin-amide
S. Lear, T. Munshi, A. S. Hudson, C. Hatton, J. Clardy, J. A. Mosely, T. J. Bull, C. S. Sit and S. L. Cobb
DOI: 10.1039/C6OB00631K, Paper


ent-Abietane diterpenoids with anti-neuroinflammatory activity from the rare Chloranthaceae plant Chloranthus oldhamii
Juan Xiong, Zhi-Lai Hong, Peng Xu, Yike Zou, Shang-Bo Yu, Guo-Xun Yang and Jin-Feng Hu
DOI: 10.1039/C6OB00731G, Paper


Concise total synthesis of (±)-serotobenine
Kangjiang Liang, Ting Wu and Chengfeng Xia
DOI: 10.1039/C6OB00682E, Paper


Synthesis of substituted tetrahydroisoquinolines by lithiation then electrophilic quench
Ruaa A. Talk, Alexia Duperray, Xiabing Li and Iain Coldham
DOI: 10.1039/C6OB00577B, Paper


Concise synthesis of calystegines B2 and B3via intramolecular Nozaki–Hiyama–Kishi reaction
Hong-Yao Wang, Atsushi Kato, Kyoko Kinami, Yi-Xian Li, George W. J. Fleet and Chu-Yi Yu
DOI: 10.1039/C6OB00697C, Paper


Synthetic investigation toward apigenin 5-O-glycoside camellianin B as well as the chemical structure revision
Yang Hu, Yuan-Hong Tu, De-Yong Liu, Jin-Xi Liao and Jian-Song Sun
DOI: 10.1039/C6OB00655H, Paper


Hydrohalogenative aromatization of multiynes promoted by ruthenium alkylidene complexes
Rajdip Karmakar, Kung-Pern Wang, Sang Young Yun, Phani Mamidipalli and Daesung Lee
DOI: 10.1039/C6OB00524A, Communication


We hope you enjoy this selection!
Why not submit your latest natural product research to OBC today?

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What are your colleagues reading in Natural Product Reports?

The articles below are some of the most read Natural Product Reports articles in January, February and March 2016.

Franz Bucar, Abraham Wube and Martin Schmid
DOI: 10.1039/C3NP20106F, Review Article

Marine natural products
John W. Blunt, Brent R. Copp, Robert A. Keyzers, Murray H. G. Munro and Michèle R. Prinsep
DOI: 10.1039/C5NP00156K, Review Article

Metabolomics in chemical ecology
Constanze Kuhlisch and Georg Pohnert
DOI: 10.1039/C5NP00003C, Review Article

Defensive symbioses of animals with prokaryotic and eukaryotic microorganisms
Laura V. Flórez, Peter H. W. Biedermann, Tobias Engl and Martin Kaltenpoth
DOI: 10.1039/C5NP00010F, Review Article

Biosynthesis of fungal meroterpenoids
Yudai Matsuda and Ikuro Abe
DOI: 10.1039/C5NP00090D, Review Article

Marine natural products
John W. Blunt, Brent R. Copp, Robert A. Keyzers, Murray H. G. Munro and Michèle R. Prinsep
DOI: 10.1039/C4NP00144C, Review Article

Prospecting for new bacterial metabolites: a glossary of approaches for inducing, activating and upregulating the biosynthesis of bacterial cryptic or silent natural products
Joseph Scott Zarins-Tutt, Tania Triscari Barberi, Hong Gao, Andrew Mearns-Spragg, Lixin Zhang, David J. Newman and Rebecca Jane Miriam Goss
DOI: 10.1039/C5NP00111K, Review Article

Recent advances in engineering nonribosomal peptide assembly lines
M. Winn, J. K. Fyans, Y. Zhuo and J. Micklefield
DOI: 10.1039/C5NP00099H, Review Article

Mass spectrometry imaging of plant metabolites – principles and possibilities
Nanna Bjarnholt, Bin Li, Janina D’Alvise and Christian Janfelt
DOI: 10.1039/C3NP70100J, Review Article

Ester coupling reactions – an enduring challenge in the chemical synthesis of bioactive natural products
Michail Tsakos, Eva S. Schaffert, Lise L. Clement, Nikolaj L. Villadsen and Thomas B. Poulsen
DOI: 10.1039/C4NP00106K, Review Article

Bacterial terpene cyclases
Jeroen S. Dickschat
DOI: 10.1039/C5NP00102A, Review Article

Natural product and natural product derived drugs in clinical trials
Mark S. Butler, Avril A. B. Robertson and Matthew A. Cooper
DOI: 10.1039/C4NP00064A, Review Article

Don’t forget to take a look at our recent themed issues on:
Biosynthetic Assembly Lines
Strategies for Cellular Target Identification of Natural Products

Keep up-to-date with the latest issues of Natural Product Reports with our E-alerts

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Balticum Organicum Syntheticum (BOS) conference 2016

Balticum Organicum Syntheticum (BOS) conference 2016

3rd – 6th July 2016, Riga, Latvia

Natural Product Reports and Organic & Biomolecular Chemistry are pleased to support the 2016 BOS conference.  The conference aims to provide a forum for organic synthetic chemists to speak of their work and discuss important scientific problems and to promote discussion between academic and industrial scientists about the possibilities of mutual cooperation.

This international conference has a balanced program of academic and industrial speakers presenting fundamental and practical aspects of organic synthesis.  This year the speakers include:

  • Emily Balskus (Harvard University, USA) Chemical Discovery in the Microbial World
  • Inga Cikotiené (Vilnius University, Lithuania) From Curiosity to Development of New Synthetic Methods
  • Nuno Maulide (University of Vienna, Austria) Catalytic Rearrangements: Inspiration for Methods and Total Synthesis
  • Per-Ola Norrby (AstraZeneca, Sweden) Predictive Chemistry: Virtual Screening in Asymmetric Catalysis
  • Virgil Percec (University of Pennsylvania, USA) A Materials Genome Approach to Mimics of Biological Membranes and their Programmable Glycan Ligands
  • Stefan Schunk (Grünenthal GmbH, Germany) Cebranopadol, A Novel Analgesic – It’s Discovery from the MedChem Perspective
  • Ryan Shenvi (The Scripps Research Institute) Chemical Synthesis of Secondary Metabolites
  • John Sutherland (MRC Laboratory of Molecular Biology, Cambridge UK) Origins of Life Systems Chemistry
  • Māris Turks (Riga Technical University, Latvia) Sulfer Dioxide: Useful Reagent and Solvent in Organic Chemistry

For more information and to register please visit the website.

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Natural Products in OBC

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although signing up to OBC’s e-alert (free service) means you will receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

Synthesis of new dicinnamoyl 4-deoxy quinic acid and methyl ester derivatives and evaluation of the toxicity against the pea aphid Acyrthosiphon pisum
Xiubin Li, Lucie Grand, Thomas Pouleriguen, Yves Queneau, Pedro da Silva, Yvan Rahbé, Jean-Luc Poëssel and Sylvie Moebs-Sanchez
DOI: 10.1039/C5OB02483H, Paper


Inhibition of HL-60 cell growth via cell cycle arrest and apoptosis induction by a cycloartane–labdane heterodimer from Pseudolarix amabilis
Xinhui Tian, Niao Yang, Bo Li, Jianping Zhang, Xike Xu, Rongcai Yue, Huiliang Li, Liping Chen, Yunheng Shen and Weidong Zhang
DOI: 10.1039/C5OB02661J, Paper


A convenient approach to an advanced intermediate toward the naturally occurring, bioactive 6-substituted 5-hydroxy-4-aryl-1H-quinolin-2-ones
Sebastián O. Simonetti, Enrique L. Larghi and Teodoro S. Kaufman
DOI: 10.1039/C5OB02680F, Paper


Talaroketals A and B, unusual bis(oxaphenalenone) spiro and fused ketals from the soil fungus Talaromyces stipitatus ATCC 10500
Yi Zang, Grégory Genta-Jouve, Pascal Retailleau, Alexandre Escargueil, Stéphane Mann, Bastien Nay and Soizic Prado
DOI: 10.1039/C5OB02657A, Paper


A bio-inspired synthetic route to the core ring systems of Spiraea atisine-type diterpenoid alkaloids and related diterpenes
Dai-Hui Tang, Ding Ma, Hang Cheng, Yong-Li Li and Liang Xu
DOI: 10.1039/C6OB00053C, Paper


Synthesis of rocaglamide derivatives and evaluation of their Wnt signal inhibitory activities
Midori A. Arai, Yuuki Kofuji, Yuuki Tanaka, Natsuki Yanase, Kazuki Yamaku, Rolly G. Fuentes, Utpal Kumar Karmakar and Masami Ishibashi
DOI: 10.1039/C5OB02537K, Paper


Four new carbazole alkaloids from Murraya koenigii that display anti-inflammatory and anti-microbial activities
Yedukondalu Nalli, Vidushi Khajuria, Shilpa Gupta, Palak Arora, Syed Riyaz-Ul-Hassan, Zabeer Ahmed and Asif Ali
DOI: 10.1039/C6OB00267F, Paper


Solution-state conformations of natural products from chiroptical spectroscopy: the case of isocorilagin
R. F. Sprenger, S. S. Thomasi, A. G. Ferreira, Q. B. Cass and J. M. Batista Junior
DOI: 10.1039/C6OB00049E, Paper


A single terpene synthase is responsible for a wide variety of sesquiterpenes in Sorangium cellulosum Soce56
Alexander Schifrin, Yogan Khatri, Philine Kirsch, Verena Thiel, Stefan Schulz and Rita Bernhardt
DOI: 10.1039/C6OB00130K, Paper


Synthesis and absolute configuration assignment of albucidin: a late-stage reductive deiodination by visible light photocatalysis
Hu Zhang, Peng-Fei Liu, Qiong Chen, Qiong-You Wu, Anne Seville, Yu-Cheng Gu, John Clough, Shao-Lin Zhou and Guang-Fu Yang
DOI: 10.1039/C6OB00371K, Paper


We hope you enjoy this selection!
Why not submit your latest natural product research to OBC today?

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New Editorial Board Members

We are very pleased to welcome two new members to our Natural Product Reports Editorial Board. Professor Janet Smith (University of Michigan, USA) and Dr Olga Genilloud (Fundación MEDINA, Spain).

Professor Janet Smith obtained her PhD in Biochemistry from the University of Wisconsin-Madison in 1978. After postdoctoral studies at the Naval Research Laboratory, she was an associate research scientist at Columbia University.  Professor Smith moved to Purdue University and established a research program in structural biology in 1987, where she remained as Professor of Biological Sciences until moving to the Life Science Institute, University of Michigan, in 2005. She is currently Margaret J. Hunter Collegiate Professor in the Life Sciences, Professor of Biological Chemistry and Director of the Centre for Structural Biology at University of Michigan.

Her research focuses on:

  • Understanding protein structure and function using X-ray crystallography as a structural tool
  • Examining the structures of proteins from infectious pathogens including the RNA viruses that cause West Nile disease, yellow fever, and dengue hemorrhagic fever
  • Understanding the operation of biosynthetic assembly lines for natural products and the activity and selectivity of enzymes that catalyse unusual reactions in natural product biosynthesis

Dr Olga Genilloud obtained her PhD in Biochemistry and Molecular Genetics from the Universidad Complutense de Madrid in 1988. Following this she joined the Drug Discovery Research Center at Merck Sharp and Dohme in Spain were she led the bacterial natural products program. In 2009 she was appointed Scientific Director at Fundación MEDINA and Head of the Microbiology department.

Her main research interests are focused on:

  • The production of novel microbial natural products
  • The exploration of novel microbial diversity to deliver novel chemistry
  • The development of molecular and chemical tools to support natural products drug discovery and the identification of potential new therapeutics

Find out more about the other members of our Editorial and Advisory Boards here.

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Natural Products in OBC

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although signing up to OBC’s e-alert (free service) means you will receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

The chemical synthesis of aryltetralin glycosides
Jian-Song Sun, Hui Liu, Xiao-Hong Guo and Jin-Xi Liao
DOI: 10.1039/C5OB02188J, Review Article


Highly efficient synthesis of flavonol 5-O-glycosides with glycosyl ortho-alkynylbenzoates as donors
Jin-Xi Liao, Nai-Li Fan, Hui Liu, Yuan-Hong Tu and Jian-Song Sun
DOI: 10.1039/C5OB02313K, Communication


Trichiconlides A and B: two novel limonoids from the fruits of Trichilia connaroides
Fa-Liang An, Jun Luo, Xiao-Bing Wang, Ming-Hua Yang and Ling-Yi Kong
Journal Article Org. Biomol. Chem., 2016,14, 1231-1235
DOI: 10.1039/C5OB02300A, Communication


Synthesis of highly enantio-enriched stereoisomers of hydroxy-GR24
J. C. Morris and C. S. P. McErlean
DOI: 10.1039/C5OB02349A, Communication


Divergent synthetic route to new cyclopenta[c]pyran iridoids: syntheses of jatamanin A, F, G and J, gastrolactone and nepetalactone
Jaehoon Sim, Inah Yoon, Hwayoung Yun, Hongchan An and Young-Ger Suh
DOI: 10.1039/C5OB02147B, Paper


Total synthesis of the azolemycins
Zoe J. Anderson and David J. Fox
DOI: 10.1039/C5OB02520F, Paper


Chemoselective room temperature E1cB NN cleavage of oxazolidinone hydrazides from enantioselective aldehyde α-hydrazination: synthesis of (+)-1,4-dideoxyallonojirimycin
Jasmin Ferreira, Sophie C. M. Rees-Jones, Valerie Ramaotsoa, Ath’enkosi Msutu and Roger Hunter
DOI: 10.1039/C5OB02560E, Communication


Marine AChE inhibitors isolated from Geodia barretti: natural compounds and their synthetic analogs
Elisabeth K. Olsen, Espen Hansen, Lindon W. K. Moodie, Johan Isaksson, Kristina Sepčić, Marija Cergolj, Johan Svenson and Jeanette H. Andersen
Journal Article Org. Biomol. Chem., 2016,14, 1629-1640
DOI: 10.1039/C5OB02416A, Paper


Total synthesis and stereochemical revision of xiamenmycin A
Xiaozhen Jiao, Yangyang Yao, Beibei Yang, Xiaoyu Liu, Xiaoyu Li, Hongguang Yang, Li Li, Jun Xu, Minjuan Xu and Ping Xie
DOI: 10.1039/C5OB02476E, Paper


Total synthesis of (±)-epithuriferic acid methyl ester via Diels–Alder reaction
Marek Koprowski, Piotr Bałczewski, Krzysztof Owsianik, Ewa Różycka-Sokołowska and Bernard Marciniak
DOI: 10.1039/C5OB02368H, Paper


Target-specific identification and characterization of the putative gene cluster for brasilinolide biosynthesis revealing the mechanistic insights and combinatorial synthetic utility of 2-deoxy-L-fucose biosynthetic enzymes
Hsien-Tai Chiu, Chien-Pao Weng, Yu-Chin Lin and Kuan-Hung Chen
DOI: 10.1039/C5OB02292D, Paper
From themed collection: 2016 Hot Articles in Organic and Biomolecular Chemistry


Solution-phase synthesis and biological evaluation of triostin A and its analogues
Kozo Hattori, Kota Koike, Kensuke Okuda, Tasuku Hirayama, Masahiro Ebihara, Mei Takenaka and Hideko Nagasawa
DOI: 10.1039/C5OB02505B, Paper


We hope you enjoy this selection!
Why not submit your latest natural product research to OBC today?

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Natural Products in OBC

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although signing up to OBC’s e-alert (free service) means you will receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

Chemical chain termination resolves the timing of ketoreduction in a partially reducing iterative type I polyketide synthase
Hirokazu Kage, Elena Riva, James S. Parascandolo, Martin F. Kreutzer, Manuela Tosin and Markus Nett
DOI: 10.1039/C5OB02009C, Communication


The biosynthesis of allelopathic di-C-glycosylflavones from the roots of Desmodium incanum (G. Mey.) DC
Bing Hao, John C. Caulfield, Mary L. Hamilton, John A. Pickett, Charles A. O. Midega, Zeyaur R. Khan, Junru R. Wang and Antony M. Hooper
DOI: 10.1039/C5OB01926E, Paper


A novel C,D-spirodioxene taxoid synthesized through an unexpected Pd-mediated ring cyclization
Shao-Rong Wang, Pedro A. Sánchez-Murcia, Federico Gago and Wei-Shuo Fang
DOI: 10.1039/C5OB02131F, Paper


Total synthesis of a piperidine alkaloid, microcosamine A
Chada Raji Reddy, Bellamkonda Latha, Kamalkishor Warudikar and Kiran Kumar Singarapu
DOI: 10.1039/C5OB02085A, Paper


The structure of tagetitoxin
Abil E. Aliev, Kersti Karu, Robin E. Mitchell and Michael J. Porter
DOI: 10.1039/C5OB02076J, Paper


Total synthesis and preliminary SAR study of (±)-merochlorins A and B
Hongzhi Yang, Xue Liu, Qingong Li, Longbo Li, Jing-Ren Zhang and Yefeng Tang
DOI: 10.1039/C5OB01946J, Paper
From themed collection 2016 Hot Articles in Organic and Biomolecular Chemistry


A method for investigating the stereochemical course of terpene cyclisations
Patrick Rabe, Jan Rinkel, Tim A. Klapschinski, Lena Barra and Jeroen S. Dickschat
DOI: 10.1039/C5OB01998B, Paper


Stereoselective total synthesis of (−)-nupharamine utilizing an α-chlorosulfide and a sulfinimine for C–C bond formation
Sadagopan Raghavan and Sheelamanthula Rajendar
DOI: 10.1039/C5OB01750E, Paper


Antimalarial diterpenoid dimers of a new carbon skeleton from Aphanamixis grandifolia
Hua Zhang, Jia Liu, Li-She Gan, Seema Dalal, Maria B. Cassera and Jian-Min Yue
DOI: 10.1039/C5OB02296G, Paper


Chemical constituents of the soft corals Sinularia vanderlandi and Sinularia gravis from the coast of Madagascar
Marie Pascaline Rahelivao, Margit Gruner, Tilo Lübken, Daut Islamov, Olga Kataeva, Hanta Andriamanantoanina, Ingmar Bauer and Hans-Joachim Knölker
DOI: 10.1039/C5OB02280K, Paper
From themed collection 2016 Hot Articles in Organic and Biomolecular Chemistry


We hope you enjoy this selection!
Why not submit your latest natural product research to OBC today?

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Natural Products in OBC – our latest selection

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although signing up to OBC’s e-alert (free service) means you will receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

Total synthesis and absolute stereochemistry of the proteasome inhibitors cystargolides A and B
Rodolfo Tello-Aburto, Liam P. Hallada, Doleshwar Niroula and Snezna Rogelj
DOI: 10.1039/C5OB01821H, Communication


Investigations into the binding of jadomycin DS to human topoisomerase IIβ by WaterLOGSY NMR spectroscopy
Camilo F. Martinez-Farina, Nicole McCormick, Andrew W. Robertson, Helen Clement, Alison Jee, Anna Ampaw, Nei-Li Chan, Ray T. Syvitski and David L. Jakeman
DOI: 10.1039/C5OB01508A, Paper


The energetic viability of an unexpected skeletal rearrangement in cyclooctatin biosynthesis
Young J. Hong and Dean J. Tantillo
DOI: 10.1039/C5OB01785H, Communication
From themed collection 2015 Hot Articles in Organic and Biomolecular Chemistry


Synthetic studies on the bioactive tetramic acid JBIR-22 using a late stage Diels–Alder reaction
A. R. Healy and N. J. Westwood
DOI: 10.1039/C5OB01771H, Paper


The first total synthesis of (+)-goniothalesacetate and syntheses of (+)-altholactone, (+)-gonioheptolide A, and (−)-goniofupyrone by an asymmetric acetate aldol approach
Sandeep AnkiReddy, Praveen AnkiReddy and Gowravaram Sabitha
DOI: 10.1039/C5OB01598G, Paper


4π electrocyclisation in domino processes: contemporary trends and synthetic applications towards natural products
Nadeem S. Sheikh
DOI: 10.1039/C5OB01703C, Review Article


Total synthesis of calothrixin B via sequential Sonogashira coupling/copper-catalyzed oxidative cyclization
Nagarajan Ramkumar and Rajagopal Nagarajan
DOI: 10.1039/C5OB01766A, Paper


Practical isolation of polygodial from Tasmannia lanceolata: a viable scaffold for synthesis
Jeremy Just, Timothy B. Jordan, Brett Paull, Alex C. Bissember and Jason A. Smith
DOI: 10.1039/C5OB01573A, Paper


Chemoenzymatic collective synthesis of optically active hydroxyl(methyl)tetrahydronaphthalene-based bioactive terpenoids
Ramesh U. Batwal and Narshinha P. Argade
DOI: 10.1039/C5OB01740H, Paper


We hope you enjoy this selection!
Why not submit your latest natural product research to OBC today?

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Ryan Shenvi wins 2016 NPR Emerging Investigator Lectureship

NPR Emerging Investigator Lectureship 2016We are delighted to announce that Professor Ryan Shenvi from the Scripps Research Institute in San Diego (USA) is the winner of the 2016 NPR Emerging Investigator Lectureship.

The NPR Lectureship is an annual event which is held at an international meeting, the recipient being a researcher who has made a significant contribution to any natural products-related research in their early independent career.

The conference at which the lecture will be delivered will be announced in due course.

Read more on Ryan’s research on the Shenvi lab homepage.

Previous winners include:

Seth Herzon, Yale University, USA (2015 winner)
Emily Balskus, Harvard University, USA (2014 winner)
Rebecca Goss, University of St Andrews, UK (2013 winner)
Dean Tantillo, UC Davis Chemistry, USA (2012 winner)

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