Archive for the ‘News’ Category

National Retrosynthesis Competition Final

On Friday the 27th of February, Burlington House was the venue for the final of the 2nd National Retrosynthesis Competition. This event was jointly organised by the Heterocyclic and Synthesis Group of the Royal Society of Chemistry, and the Fine Chemicals Group and Young Chemists Panel of the SCI, under the lead of Rob Wybrow of Syngenta, UK.

From 50 teams who entered the preliminary round in December 2014, 10 were selected for the final by the judging panel, Professor Chris Willis (Bristol University), Professor Rob Stockman (Nottingham University), Dr Wes Heaton (GSK) and Dr Mike Mortimore (Vertex). The finalists were drawn from a broad cross-section of chemistry-based organisations, universities and academic institutions, pharmaceutical companies, CROs and agrochemicals.

In the final, teams presented their synthetic strategies for the recently identified, as yet unsynthesized natural product, alistonitrine A, and answered questions from the audience challenging their reasoning and route selection. Trophies for the winning teams were generously provided by Chemglass Life Sciences, and the overall winners received an additional prize of a year’s subscription to Natural Product Reports, provided by the Royal Society of Chemistry.

The winning team “One ED”, representing Charles River Laboratories, received a Huber Unichiller 003-MPC (donated by Huber). The runners up were “Oxford SBM Team” from Oxford University who received a Flashforge Creator 3D Printer  (donated by Chemglass Life Sciences), and the third place on the podium was taken by “Team Dalton Towers” from the University of Manchester, who received a J Young 5 port Vacuum Manifold (donated by GPE).

The organising committee would like to thank all of the teams who entered for their contributions, the finalists, judges, guests, attendees, sponsors and exhibitors for their significant input into the event. Based upon enthusiastic positive feedback from participants and special guests on the day the competition was hugely successful, underlining the key central importance of synthetic organic chemistry in both fundamental and applied research in the UK. Taking that positive momentum forwards, the organising committee has already begun their planning for the 3rd National Retrosynthesis Competition, to be held in early March 2016.

Retrosynthesis winners “One ED” from Charles River Laboratories

Digg This
Reddit This
Stumble Now!
Share on Facebook
Bookmark this on Delicious
Share on LinkedIn
Bookmark this on Technorati
Post on Twitter
Google Buzz (aka. Google Reader)

Poster Prize winners at Directing Biosynthesis IV

3 Poster prizes were awarded on the occasion of the Directing Biosynthesis IV conference held in Norwich, 25-27 March 2015.
Congratulations to you all!

Chemical Science poster award
Catherine Hubert (King’s College London, UK)
Poster title: Elucidation of a novel nitric oxide synthase containing biosynthetic pathway

Organic & Biomolecular Chemistry poster award
Maximilian Helf (ETH Zurich, Switzerland)
Poster title: Exploring the proteusin family of natural products

Maximilian tells us a few words about his research:
‘The giant peptide toxins polytheonamides are produced by a bacterial symbiont of the marine sponge Theonella swinhoei. The biosynthesis of these natural products involves highly unusual modifications of a precursor peptide, including 18 amino acid epimerizations and eight N-methylations of asparagine residues. Polytheonamides and putative natural products derived from related precursor peptides constitute a new family of ribosomally synthesized and post-translationally modified peptide natural products (RiPPs), the proteusins. Many of the predicted biosynthetic gene clusters for proteusins encode enzymes of unknown function. Using heterologous expression and culturing approaches, we are prospecting these systems for novel enzyme types, with a focus on sponge symbionts and cyanobacteria.’

Natural Product Reports poster award
Marie Yurkovitch (University of Cambridge, UK)
Poster title: Catramycin: A novel immunosuppressant molecule

From left to right: Marie Cote (Deputy editor, NPR), Maximilian Helf, Catherine Hubert, Maria Yurkovich and Brad Moore (NPR Chair)

Digg This
Reddit This
Stumble Now!
Share on Facebook
Bookmark this on Delicious
Share on LinkedIn
Bookmark this on Technorati
Post on Twitter
Google Buzz (aka. Google Reader)

Emily Balskus receives NPR Lectureship at Directing Biosynthesis IV

Emily Balskus, winner of the 2014 NPR Emerging Investigator Lectureship, delivered her lecture entitled ‘Chemical discovery in the microbial world’ at Directing Biosynthesis IV

Chair of the Editorial Board Prof. Brad Moore was delighted to present Emily with the award. The NPR Lectureship is an annual event which is held at an international meeting, the recipient being a researcher who has made a significant contribution to any natural products-related research in their early independent career.

Read more on Emily’s research on the Balskus lab Homepage

Current and previous winners include:

Seth Herzon, Yale University, USA (2015 winner)
Rebecca Goss, University of St Andrews, UK (2013 winner)
Dean Tantillo, UC Davis Chemistry, USA (2012 winner)

Congratulations Emily!

Brad Moore, Chair of the NPR Editorial Board, presents Emily Balskus with her Lectureship

Emily about to present her lectureship talk on Chemical Discovery in the Microbial World

Digg This
Reddit This
Stumble Now!
Share on Facebook
Bookmark this on Delicious
Share on LinkedIn
Bookmark this on Technorati
Post on Twitter
Google Buzz (aka. Google Reader)

Seth Herzon wins 2015 NPR Emerging Investigator Lectureship

Seth Herzon winner of the 2015 NPR Emerging Investigator LectureshipWe are delighted to announce that Professor Seth Herzon from Yale University (USA) is the winner of the 2015 NPR Emerging Investigator Lectureship.

The NPR Lectureship is an annual event which is held at an international meeting, the recipient being a researcher who has made a significant contribution to any natural products-related research in their early independent career.

The conference at which the lecture will be delivered will be announced in due course.

Read more on Seth’s research on the Herzon lab Homepage

Previous winners include:

Emily Balskus, Harvard University, USA (2014 winner)
Rebecca Goss, University of St Andrews, UK (2013 winner)
Dean Tantillo, UC Davis Chemistry, USA (2012 winner)

Digg This
Reddit This
Stumble Now!
Share on Facebook
Bookmark this on Delicious
Share on LinkedIn
Bookmark this on Technorati
Post on Twitter
Google Buzz (aka. Google Reader)

Natural Product Reports Emerging Investigator Lectureship – nominate now!

Nominations are now open for the 2015 Natural Product Reports Emerging Investigator Lectureship.

Nominate by Friday 26th September 2014

The Lectureship recognises a researcher who has made a significant contribution to a natural products-related area of the chemical sciences in their early independent career. Nominations can be made by anyone, so why not nominate a colleague, collaborator, or someone whose work you admire today?

To qualify
To be eligible for the Natural Product Reports Emerging Investigator Lectureship, the candidate should have completed their PhD on or after 31st December 2005.

Lectureship details
The recipient will be invited to present a lecture at a conference during 2015. They will receive £500 towards travel and accommodation costs. They will also be presented with a certificate and be asked to contribute a Natural Product Reports article.

Nominations
Those wishing to make a nomination should send the following details to the Natural Product Reports Editorial Office by Friday 26th September 2014:

  • The name, affiliation and (if possible) web address of the nominee
  • A paragraph outlining the reasons for nomination. This should include brief details of the nominee’s contributions to their field

Selection procedure
The  Natural Product Reports Editorial Board will draw up a short-list of candidates based on the information provided at nomination. The board will then vote to select the recipient at the Autumn Editorial Board meeting, and the winner will be announced in late 2014.

Previous Winners
2013: Rebecca Goss – University of St Andrews, UK
2014: Emily Balskus – Harvard University, USA

Digg This
Reddit This
Stumble Now!
Share on Facebook
Bookmark this on Delicious
Share on LinkedIn
Bookmark this on Technorati
Post on Twitter
Google Buzz (aka. Google Reader)

RSC Organic Division Poster Symposium 2014

RSC Organic Division Poster Symposium 2014, headline sponsored by F. Hoffmann-La Roche, Ltd.

The poster symposium, for final year organic chemistry PhD students, will take place at The Royal Society of Chemistry, Burlington House, London on Monday 01 December 2014.

The symposium offers final year PhD students a chance to showcase their research to their peers, leading academics and industrial chemists, and is open to all branches of organic chemistry. The symposium has a tradition of being the most competitive and highly regarded organic chemistry symposium for PhD students in the UK and ROI and we would like to thank F. Hoffmann-La Roche, Ltd. for their generous support of the event.

There will be a first prize of £500, two runner-up prizes of £250, and a “selected by Industry Prize”. Industrial delegates will make this selection by considering the research’s potential for application in an industrial context; the winner will also receive a prize of £500.

Closing date for submissions is Wednesday 01 October 2014.
For more information and to submit your abstract go to http://rsc.li/organic-poster

Digg This
Reddit This
Stumble Now!
Share on Facebook
Bookmark this on Delicious
Share on LinkedIn
Bookmark this on Technorati
Post on Twitter
Google Buzz (aka. Google Reader)

Make your journal work for you

Want to know about the latest research we publish in Natural Product Reports? Want to be told about upcoming themed issues, or the most read articles, or other journal news?

Here are a few ways you can stay in touch with us and all that is happening:

RSS Feed for Natural Product ReportsMost recent articles

Be informed about the latest articles published on our website by adding us to your RSS Feed.


Issue alerts

Sign-up to NPR issue alertsGet the table of contents of the latest issue of Natural Product Reports sent direct to you when we publish the issue.


News alerts

Register for NPR news alertsBy joining our news alerts we can let you know about:

  • Up-coming themed collections (print & electronic)
  • Top Ten most accessed articles
  • Changes to our Editorial Board
  • Important news for the journal


Twitter

Follow Natural Product Reports on twitter

We can also be found on Twitter @NatProdRep, add us and say hello.


And of course you can always come back to this blog to find out about our journal news.

Digg This
Reddit This
Stumble Now!
Share on Facebook
Bookmark this on Delicious
Share on LinkedIn
Bookmark this on Technorati
Post on Twitter
Google Buzz (aka. Google Reader)

Emily Balskus wins 2014 NPR Emerging Investigator Lectureship


We are delighted to announce that Dr Emily Balskus from Harvard University (USA) is the winner of the 2014 NPR Emerging Investigator Lectureship.

The NPR Lectureship is an annual event which is held at an international meeting, the recipient being a researcher who has made a significant contribution to any natural products-related research in their early independent career.

The conference at which the lecture will be delivered will be announced in due course.

Read more on Emily’s research on the Balskus lab Homepage

Previous winners include:
Rebecca Goss, University of St Andrews, UK (2013 winner)
Dean Tantillo, UC Davis Chemistry, USA (2012 winner)

Digg This
Reddit This
Stumble Now!
Share on Facebook
Bookmark this on Delicious
Share on LinkedIn
Bookmark this on Technorati
Post on Twitter
Google Buzz (aka. Google Reader)

Nominate now for the Natural Product Reports 2014 Lectureship!

 Nominations are now open for the 2014 NPR Emerging Investigator Lectureship.

The Lectureship recognises a researcher who has made a significant contribution to a natural products-related area of the chemical sciences in their early independent career. The winner will deliver their lecture at an international meeting in the coming year.

Nominees should have completed their PhD on or after the 31st December 2001.

To nominate someone simply contact NPR Editor, Richard Kelly. All you need to provide are the name of the nominee and some very brief information about why you are nominating them. Nominations are open to everyone and should be received by 25th February 2014.

The winner will be selected by an Editorial Board panel and the result will be announced in Spring 2014.

The winner for the 2013 Lectureship was Rebecca Goss from University of St Andrews, UK.

Digg This
Reddit This
Stumble Now!
Share on Facebook
Bookmark this on Delicious
Share on LinkedIn
Bookmark this on Technorati
Post on Twitter
Google Buzz (aka. Google Reader)

Q2 Top 10 for Natural Product Reports

Please take a look at the top 10 most accessed Natural Product Reports articles for the second quarter of 2013:

Natural product isolation – how to get from biological material to pure compounds  
Franz Bucar, Abraham Wube and Martin Schmid  
Nat. Prod. Rep., 2013, 30, 525-545  
DOI: 10.1039/C3NP20106F 

Marine natural products  
John W. Blunt, Brent R. Copp, Robert A. Keyzers, Murray H. G. Munro and Michèle R. Prinsep   
Nat. Prod. Rep., 2013, 30, 237-323  
DOI: 10.1039/C2NP20112G 

Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature  
Wilfred A. van der Donk, et al.
Nat. Prod. Rep., 2013, 30, 108-160    
DOI: 10.1039/C2NP20085F

Marine natural products: synthetic aspects 
Jonathan C. Morris   
Nat. Prod. Rep., 2013, 30, 783-805  
DOI: 10.1039/C3NP20116C 

Hot off the press  
Robert A. Hill and Andrew Sutherland 
Nat. Prod. Rep., 2013, 30, 760-764  
DOI: 10.1039/C3NP90015K  

The antibody-drug conjugate: an enabling modality for natural product-based cancer therapeutics  
Hans-Peter Gerber, Frank E. Koehn and Robert T. Abraham   
Nat. Prod. Rep., 2013, 30, 625-639  
DOI: 10.1039/C3NP20113A 

The enzymes of β-lactam biosynthesis 
Refaat B. Hamed, J. Ruben Gomez-Castellanos, Luc Henry, Christian Ducho, Michael A. McDonough and Christopher J. Schofield 
Nat. Prod. Rep., 2013, 30, 21-107  
DOI: 10.1039/C2NP20065A 

Simple indole alkaloids and those with a non-rearranged monoterpenoid unit  
Minoru Ishikura, Takumi Abe, Tominari Choshi and Satoshi Hibino  
Nat. Prod. Rep., 2013, 30, 694-752  
DOI: 10.1039/C3NP20118J 

Using NMR to identify and characterize natural products  
Rosemary C. Breton and William F. Reynolds   
Nat. Prod. Rep., 2013, 30, 501-524  
DOI: 10.1039/C2NP20104F 

Perspectives on natural product epigenetic modulators in chemical biology and medicine  
Fanny L. Cherblanc, Robert W. M. Davidson, Paolo Di Fruscia, Nitipol Srimongkolpithak and Matthew J. Fuchter 
Nat. Prod. Rep., 2013, 30, 605-624  
DOI: 10.1039/C3NP20097C 

We very much welcome your thoughts and comments about this blog below:

Fancy submitting an article to Natural Product Reports? Then why not submit to us today or alternatively email us your suggestions.

Digg This
Reddit This
Stumble Now!
Share on Facebook
Bookmark this on Delicious
Share on LinkedIn
Bookmark this on Technorati
Post on Twitter
Google Buzz (aka. Google Reader)