Archive for the ‘Natural Products in OBC’ Category

Natural Products in OBC

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although signing up to OBC’s e-alert (free service) means you will receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

Bioinspired total syntheses of terpenoids
Cedric L. Hugelshofer and Thomas Magauer
DOI: 10.1039/C6OB02488B, Perspective

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Total synthesis and confirmation of the revised structures of jiangrines A, C and D
Zhijiang Zhang and Bo Liu
DOI: 10.1039/C6OB02379G, Paper

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Fluorometabolite biosynthesis: isotopically labelled glycerol incorporations into the antibiotic nucleocidin in Streptomyces calvus
Axel Bartholomé, Jeffrey E. Janso, Usa Reilly and David O’Hagan
DOI: 10.1039/C6OB02291J, Communication

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Enantiospecific total syntheses of meroterpenoids (−)-F1839-I and (−)-corallidictyals B and D
Dattatraya H. Dethe, Balu D. Dherange, Saghir Ali and Mahesh M. Parsutkar
DOI: 10.1039/C6OB02322C, Communication

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Second-generation total synthesis of aplyronine A featuring Ni/Cr-mediated coupling reactions
Ichiro Hayakawa, Keita Saito, Sachiko Matsumoto, Shinichi Kobayashi, Ayaka Taniguchi, Kenichi Kobayashi, Yusuke Fujii, Takahiro Kaneko and Hideo Kigoshi
DOI: 10.1039/C6OB02241C, Paper

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The first total synthesis of the marine acetylenic alcohol, lembehyne B – a selective inducer of early apoptosis in leukemia cancer cells
Lilya U. Dzhemileva, Vladimir A. D’yakonov, Aleksey A. Makarov, Evgeny N. Andreev, Milyausha M. Yunusbaeva and Usein M. Dzhemilev  
DOI: 10.1039/C6OB02346K, Paper

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An efficient approach to trans-4-hydroxy-5-substituted 2-pyrrolidinones through a stereoselective tandem Barbier process: divergent syntheses of (3R,4S)-statines, (+)-preussin and (−)-hapalosin
Chang-Mei Si, Lu-Ping Shao, Zhuo-Ya Mao, Wen Zhou and Bang-Guo Wei  
DOI: 10.1039/C6OB02523D, Paper

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A protecting-group-free synthesis of (+)-nephrosteranic, (+)-protolichesterinic, (+)-nephrosterinic, (+)-phaseolinic, (+)-rocellaric acids and (+)-methylenolactocin
Jothi L. Nallasivam and Rodney A. Fernandes
DOI: 10.1039/C6OB02398C, Paper

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Stepwise cyclopropanation on the polycyclopropanated polyketide formation in jawsamycin biosynthesis
Tomoshige Hiratsuka, Hideaki Suzuki, Atsushi Minami and Hideaki Oikawa
DOI: 10.1039/C6OB02675C, Communication

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A novel withanolide with an unprecedented carbon skeleton from Physalis angulata
Cheng-Peng Sun, Andrei G. Kutateladze, Feng Zhao, Li-Xia Chen and Feng Qiu  
DOI: 10.1039/C6OB02656G, Communication

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Total synthesis and biological activity of dolastatin 16
Loida O. Casalme, Arisa Yamauchi, Akinori Sato, Julie G. Petitbois, Yasuyuki Nogata, Erina Yoshimura, Tatsufumi Okino, Taiki Umezawa and Fuyuhiko Matsuda  
DOI: 10.1039/C6OB02657E, Paper

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New compounds from a hydrothermal vent crab-associated fungus Aspergillus versicolor XZ-4
Chengqian Pan, Yutong Shi, Xuegang Chen, Chen-Tung Arthur Chen, Xinyi Tao and Bin Wu  
DOI: 10.1039/C6OB02374F, Paper

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Chemoenzymatic synthesis of unmodified heparin oligosaccharides: cleavage of p-nitrophenyl glucuronide by alkaline and Smith degradation
Xing Zhang, Yongmei Xu, Po-Hung Hsieh, Jian Liu, Lei Lin, Eric P. Schmidt and Robert J. Linhardt  
DOI: 10.1039/C6OB02603F, Paper

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Isoafricanol synthase from Streptomyces malaysiensis
Patrick Rabe, Markiyan Samborskyy, Peter F. Leadlay and Jeroen S. Dickschat  
DOI: 10.1039/C7OB00234C, Communication

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An efficient Ugi-3CR/aza Diels–Alder/Pomeranz–Fritsch protocol towards novel aza-analogues of (±)-nuevamine, (±)-lennoxamine and magallanesine: a diversity oriented synthesis approach
Óscar Vázquez-Vera, Jorge S. Sánchez-Badillo, Alejandro Islas-Jácome, Manuel A. Rentería-Gómez, Shrikant G. Pharande, Carlos J. Cortes-García, Mónica A. Rincón-Guevara, Ilich A. Ibarra, Rocío Gámez-Montaño and Eduardo González-Zamora  
DOI: 10.1039/C6OB02572B, Paper

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Intramolecular macrolactonization, photophysical and biological studies of new class of polycyclic pyrrole derivatives
Suresh Kumar Mondal, Arabinda Mandal, Susanta Kumar Manna, Sk Asraf Ali, Maidul Hossain, Vangala Venugopal, Avijit Jana and Shubhankar Samanta  
DOI: 10.1039/C7OB00160F, Paper

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Natural Products in OBC

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although signing up to OBC’s e-alert (free service) means you will receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

 

Gold catalysis: synthesis of spiro, bridged, and fused ketal natural products
Rachelle Quach, Daniel P. Furkert and Margaret A. Brimble  
DOI: 10.1039/C7OB00496F, Review Article

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Application of the aza-Diels–Alder reaction in the synthesis of natural products
Min-Hui Cao, Nicholas J. Green and Sheng-Zhen Xu  
DOI: 10.1039/C6OB02761J, Review Article

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ipso-Cyclization: an emerging tool for multifunctional spirocyclohexadienones
Chada Raji Reddy, Santosh Kumar Prajapti, Kamalkishor Warudikar, Ravi Ranjan and Billa Bhargava Rao  
DOI: 10.1039/C7OB00405B, Review Article

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cis or trans with class II diterpene cyclases
Meirong Jia and Reuben J. Peters  
DOI: 10.1039/C7OB00510E, Communication

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Enantioselective Diels-Alder-lactamization organocascades employing a furan-based diene
Mikail E. Abbasov, Brandi M. Hudson, Weixu Kong, Dean J. Tantillo and Daniel Romo  
DOI: 10.1039/C6OB02738E, Communication

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Synthesis, SAR and biological studies of sugar amino acid-based almiramide analogues: N-methylation leads the way
Dipendu Das, Hina P. A. Khan, Rahul Shivahare, Suman Gupta, Jayanta Sarkar, Mohd. Imran Siddiqui, Ravi Sankar Ampapathi and Tushar Kanti Chakraborty  
DOI: 10.1039/C6OB02610A, Paper

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JA-Ile-macrolactones uncouple growth and defense in wild tobacco
Guillermo H. Jimenez-Aleman, Ricardo A. R. Machado, Ian T. Baldwin and Wilhelm Boland  
DOI: 10.1039/C7OB00249A, Communication

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Enantioselective total synthesis of (+)-arborescidine C and related tetracyclic indole alkaloids using organocatalysis
Vishal M. Sheth, Bor-Cherng Hong and Gene-Hsiang Lee  
DOI: 10.1039/C7OB00473G, Communication

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Synthesis of AHMOD-containing aminolipopeptides, unique bioactive peptaibiotics
Louise A. Stubbing, Iman Kavianinia and Margaret A. Brimble  
DOI: 10.1039/C7OB00541E, Review Article

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Enantioselective total synthesis of colomitides and their absolute configuration determination and structural revision
Hongguang Yang, Xiaoyu Liu, Xiaoyu Li, Xiang Shi, Feilong Yang, Xiaozhen Jiao and Ping Xie  
DOI: 10.1039/C7OB00539C, Paper

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Biochemical studies of inositol N-acetylglucosaminyltransferase involved in mycothiol biosynthesis in Corynebacterium diphtheria
Yuchuan Guo, Lizhen Wang, Jiatong Guo, Guofeng Gu and Zhongwu Guo  
DOI: 10.1039/C7OB00555E, Paper

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Dissection of the neocarazostatin: a C4 alkyl side chain biosynthesis by in vitro reconstitution
Li Su, Rui Zhang, Kwaku Kyeremeh, Zixin Deng, Hai Deng and Yi Yu  
DOI: 10.1039/C7OB00617A, Communication

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Rifamorpholines A–E, potential antibiotics from locust-associated actinobacteria Amycolatopsis sp. Hca4
Yong Sheng Xiao, Bo Zhang, Mei Zhang, Zhi Kai Guo, Xin Zhao Deng, Jing Shi, Wei Li, Rui Hua Jiao, Ren Xiang Tan and Hui Ming Ge  
DOI: 10.1039/C7OB00614D, Paper

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Asymmetric synthesis of ent-fragransin C1
Santikorn Chaimanee, Manat Pohmakotr, Chutima Kuhakarn, Vichai Reutrakul and Darunee Soorukram  
DOI: 10.1039/C7OB00749C, Paper

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Natural Products in OBC

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although signing up to OBC’s e-alert (free service) means you will receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

Total synthesis based on the originally claimed structure of mucosin
Harrison C. Gallantree-Smith, Simen G. Antonsen, Carl H. Görbitz, Trond V. Hansen, Jens M. J. Nolsøe and Yngve H. Stenstrøm
DOI: 10.1039/C6OB01511E, Communication

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Synthesis and biological evaluation of palmyrolide A macrocycles as sodium channel blockers towards neuroprotection
Satish Chandra Philkhana, Suneet Mehrotra, Thomas F. Murray and D. Srinivasa Reddy
DOI: 10.1039/C6OB01372D, Paper

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Microwave assisted synthesis of phenanthridinones and dihydrophenanthridines by vasicine/KOtBu promoted intramolecular C–H arylation
Sushila Sharma, Manoranjan Kumar, Shruti Sharma, Onkar S. Nayal, Neeraj Kumar, Bikram Singh and Upendra Sharma
DOI: 10.1039/C6OB01362G, Paper

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Effective one-pot multienzyme (OPME) synthesis of monotreme milk oligosaccharides and other sialosides containing 4-O-acetyl sialic acid
Hai Yu, Jie Zeng, Yanhong Li, Vireak Thon, Baojun Shi and Xi Chen
DOI: 10.1039/C6OB01706A, Paper

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Chemoselective photooxygenations of furans bearing unprotected amines: their use in alkaloid synthesis
T. Montagnon, D. Kalaitzakis, M. Sofiadis and G. Vassilikogiannakis
DOI: 10.1039/C6OB01689H, Perspective

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A protecting group-free synthesis of (−)-hortonones A–C from the Inhoffen–Lythgoe diol
Hovsep Stambulyan and Thomas G. Minehan
DOI: 10.1039/C6OB01738J, Paper

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Total synthesis of cananginone C and structural revision of debilisone A
Tapan Kumar Kuilya and Rajib Kumar Goswami
DOI: 10.1039/C6OB01671E, Paper

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Total synthesis of mangiferin, homomangiferin, and neomangiferin
Xiong Wei, Danlin Liang, Qing Wang, Xiangbao Meng and Zhongjun Li
DOI: 10.1039/C6OB01622G, Paper

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Substitution dependent stereoselective construction of bicyclic lactones and its application to the total synthesis of pyranopyran, tetraketide and polyrhacitide A
B. V. Subba Reddy, Dhanraj O. Biradar, Y. Vikram Reddy, J. S. Yadav, Kiran Kumar Singarapu and B. Sridhar
DOI: 10.1039/C6OB01686C, Paper

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4,4′-Bismoschamine: biomimetic synthesis and evidence to support structural equivalency to montamine
Kaitlin G. Henry, Lachlan M. Blair, Jonathan Sperry and Elizabeth A. Colby Davie
DOI: 10.1039/C6OB01685E, Paper

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Total synthesis of diptoindonesin G and its analogues as selective modulators of estrogen receptors
Ji-tian Liu, Truman J. Do, Christopher J. Simmons, John C. Lynch, Wen Gu, Zhi-Xiong Ma, Wei Xu and Weiping Tang
DOI: 10.1039/C6OB01657J, Communication

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Phosphorylated cyclopropanes in the synthesis of α-alkylidene-γ-butyrolactones: total synthesis of (±)-savinin, (±)-gadain and (±)-peperomin E
Matthew G. Lloyd, Richard J. K. Taylor and William P. Unsworth
DOI: 10.1039/C6OB01527A, Paper

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De novo protecting-group-free total synthesis of (+)-muricadienin, (+)-ancepsenolide and (+)-3-hexadecyl-5-methylfuran-2(5H)-one
Rupesh A. Kunkalkar, Debasish Laha and Rodney A. Fernandes
DOI: 10.1039/C6OB01721E, Paper

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An expeditious synthesis of the ascomycete metabolite rigidiusculamide B
Anja Wunder and Rainer Schobert
DOI: 10.1039/C6OB01836J, Paper

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Total synthesis of haliclamide
Suraksha Gahalawat and Satyendra Kumar Pandey
DOI: 10.1039/C6OB01775D, Paper

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Natural Products in OBC

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although signing up to OBC’s e-alert (free service) means you will receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

Preparation of oxocene terpenes. The first enantiospecific synthesis of cytotoxic arenaran A
Alejandro Torres, Pilar Gutierrez, Ramón Alvarez-Manzaneda, Rachid Chahboun and Enrique Alvarez-Manzaneda
DOI: 10.1039/C6OB01640E, Paper

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Synthesis of crinane utilizing an allylic sulfoxide for the construction of a hydroindole ring via vinylogous C–N bond formation
Sadagopan Raghavan and Anil Ravi
DOI: 10.1039/C6OB01966H, Paper

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Total synthesis of wewakazole B
Bohua Long, Jingzhao Zhang, Xudong Tang and Zhengzhi Wu
DOI: 10.1039/C6OB01783E, Communication

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Total synthesis of (±)-ganocins B and C
Yao Liu, Chu-Jun Zhou, Qingjiang Li and Honggen Wang
DOI: 10.1039/C6OB02049F, Communication

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Stereoselective synthesis of (−)-desethyleburnamonine, (−)-vindeburnol and (−)-3-epitacamonine: observation of a substrate dependent diastereoselectivity reversal of an aldol reaction
Pravat Mondal and Narshinha P. Argade
DOI: 10.1039/C6OB01438K, Paper

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Stereoselective construction of 2-vinyl 3-hydroxybenzopyran rings: total syntheses of teadenols A and B
Ryunosuke Yoshida, Hitoshi Ouchi, Atsushi Yoshida, Tomohiro Asakawa, Makoto Inai, Masahiro Egi, Yoshitaka Hamashima and Toshiyuki Kan
DOI: 10.1039/C6OB02004F, Communication

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Total synthesis, structural elucidation and anti-inflammatory activity evaluation of 2-deoxy-3,6-anhydro hexofuranoside derivatives isolated from Sauropus rostratus
Chenxi Zhang, Chengcheng Wang, Zihao Wang, Genzoh Tanabe, Osamu Muraoka, Aijun Lin, Jinyi Xu, Xiaoming Wu, Liang Wu and Weijia Xie
DOI: 10.1039/C6OB02207C, Paper

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SCascade oxime formation, cyclization to a nitrone, and intermolecular dipolar cycloaddition
Rachel C. Furnival, Rungroj Saruengkhanphasit, Heather E. Holberry, Jonathan R. Shewring, Hélène D. S. Guerrand, Harry Adams and Iain Coldham
DOI: 10.1039/C6OB01871H, Paper

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Synthetic analogs of stryphnusin isolated from the marine sponge Stryphnus fortis inhibit acetylcholinesterase with no effect on muscle function or neuromuscular transmission
Lindon W. K. Moodie, Monika C. Žužek, Robert Frangež, Jeanette H. Andersen, Espen Hansen, Elisabeth K. Olsen, Marija Cergolj, Kristina Sepčić, Kine Ø. Hansen and Johan Svenson
DOI: 10.1039/C6OB02120D, Paper

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Macrolactam analogues of macrolide natural products
Helmut M. Hügel, Andrew T. Smith and Mark A. Rizzacasa
DOI: 10.1039/C6OB02149B, Review Article

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Enantioselective total synthesis and structural assignment of callyspongiolide
Arun K. Ghosh, Luke A. Kassekert and Joseph D. Bungard
DOI: 10.1039/C6OB02051H, Paper

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Total synthesis of natural derivatives and artificial analogs of 13-oxyingenol and their biological evaluation
Takayuki Ohyoshi, Yuki Tamura, Ichiro Hayakawa, Go Hirai, Yamato Miyazawa, Shota Funakubo, Mikiko Sodeoka and Hideo Kigoshi
DOI: 10.1039/C6OB02268E, Paper

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Natural Products in OBC

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although signing up to OBC’s e-alert (free service) means you will receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

Asymmetric synthesis and absolute stereochemistry of a labdane-type diterpenoid isolated from the rhizomes of Isodan yuennanensis
Heping Deng, Wei Cao, Zhijiang Zhang and Bo Liu
DOI: 10.1039/C6OB00750C, Paper


Biosynthesis of isoxazolin-5-one and 3-nitropropanoic acid containing glucosides in juvenile Chrysomelina
Tobias Becker, Kerstin Ploss and Wilhelm Boland
DOI: 10.1039/C6OB00899B, Paper


Overproduction and identification of butyrolactones SCB1–8 in the antibiotic production superhost Streptomyces M1152
John D. Sidda, Vincent Poon, Lijiang Song, Weishan Wang, Keqian Yang and Christophe Corre
DOI: 10.1039/C6OB00840B, Communication


Synthesis and biological evaluation of acylated oligorhamnoside derivatives structurally related to mezzettiaside-6 with cytotoxic activity
Gaopeng Song, Sumei Li, Zhiwei Lei, Yibin Li, Junhua Li, Yixian Liao and Zi-Ning Cui
DOI: 10.1039/C6OB00862C, Paper


Asymmetric synthesis of (+)-17-epi-methoxy-kauran-3-one through tandem oxidative polycyclization-pinacol process
Gaëtan Maertens, Samuel Desjardins and Sylvain Canesi
DOI: 10.1039/C6OB01142J, Paper


Enantioselective synthesis of (+)-brevipolide H
Ching-Nung Chen and Duen-Ren Hou
DOI: 10.1039/C6OB01071G, Paper


Synthetic studies of callyspongiolide: synthesis of the macrolactone core of the molecule
Sudhakar Athe, Ashish Sharma, Kanakaraju Marumudi and Subhash Ghosh
DOI: 10.1039/C6OB01007E, Paper


Synthesis of L-indospicine, [5,5,6-2H3]-L-indospicine and L-norindospicine
Cheng-Shan Lang, Siew-Hoon Wong, Sharon Chow, Victoria L. Challinor, Ken W. L. Yong, Mary T. Fletcher, Dionne M. Arthur, Jack C. Ng and James J. De Voss
DOI: 10.1039/C6OB01187J, Paper


Synthesis of 2,6-trans– and 3,3,6-trisubstituted tetrahydropyran-4-ones from Maitland–Japp derived 2H-dihydropyran-4-ones: a total synthesis of diospongin B
Paul A. Clarke, Nadiah Mad Nasir, Philip B. Sellars, Alejandra M. Peter, Connor A. Lawson and James L. Burroughs
DOI: 10.1039/C6OB01182A, Paper


Catalytic asymmetric reactions and synthesis of quinones
Basavaprabhu Hosamani, Matheus F. Ribeiro, Eufrânio N. da Silva Júnior and Irishi N. N. Namboothiri
DOI: 10.1039/C6OB01119E, Review Article


Platinum-catalyzed cycloisomerizations of a common enyne: a divergent entry to cyclopropane sesquiterpenoids. Formal synthesis of sarcandralactone A
Vera P. Demertzidou and Alexandros L. Zografos
DOI: 10.1039/C6OB011226D, Communication


Synthesis of the 2-formylpyrrole spiroketal pollenopyrroside A and structural elucidation of xylapyrroside A, shensongine A and capparisine BA
James M. Wood, Daniel P. Furkert and Margaret A. Brimble
DOI: 10.1039/C6OB01361A, Paper


Biosynthesis-driven structure–activity relationship study of premonensin-derivatives A
A. Ismail-Ali, E. K. Fansa, N. Pryk, S. Yahiaoui, S. Kushnir, M. Pflieger, A. Wittinghofer and F. Schulz
DOI: 10.1039/C6OB01201A, Paper


Horner–Wadsworth–Emmons approach to piperlongumine analogues with potent anti-cancer activity
Li-Chen Han, Paul A. Stanley, Paul J. Wood, Pallavi Sharma, Anchala I. Kuruppu, Tracey D. Bradshaw and John E. Moses
DOI: 10.1039/C6OB01160H, Paper


We hope you enjoy this selection!
Why not submit your latest natural product research to OBC today?

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Natural Products in OBC

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although signing up to OBC’s e-alert (free service) means you will receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

First total synthesis of (+)-broussonetine W: glycosidase inhibition of natural product & analogs
Ying-Ying Song, Kyoko Kinami, Atsushi Kato, Yue-Mei Jia, Yi-Xian Li, George W. J. Fleet and Chu-Yi Yu
DOI: 10.1039/C6OB00720A, Paper


Synthesis of a simplified triazole analogue of pateamine A
A. Hemi Cumming, Sarah L. Brown, Xu Tao, Claire Cuyamendous, Jessica J. Field, John H. Miller, Joanne E. Harvey and Paul H. Teesdale-Spittle
DOI: 10.1039/C6OB00086J, Paper


Studies towards the synthesis of tedanolide C. Construction of the C13-epi C1–C15 fragment
Joana Zambrana, Pedro Romea and Fèlix Urpí
DOI: 10.1039/C6OB00896H, Communication


Asymmetric synthesis of crambescin A–C carboxylic acids and their inhibitory activity on voltage-gated sodium channels
Atsuo Nakazaki, Yoshiki Nakane, Yuki Ishikawa, Mari Yotsu-Yamashita and Toshio Nishikawa
DOI: 10.1039/C6OB00914J, Paper


Nitropyrrole natural products: isolation, biosynthesis and total synthesis
Xiao-Bo Ding, Margaret A. Brimble and Daniel P. Furkert
DOI: 10.1039/C5OB02599K, Review Article


Some chemical speculation on the biosynthesis of corallidictyals A–D
Adrian W. Markwell-Heys and Jonathan H. George
DOI: 10.1039/C6OB00171H, Communication


First total synthesis of trehalose containing tetrasaccharides from Mycobacterium smegmatis
Manishkumar A. Chaube, Vikram A. Sarpe, Santanu Jana and Suvarn S. Kulkarni
DOI: 10.1039/C6OB00412A, Communication


Towards theory driven structure elucidation of complex natural products: mandelalides and coibamide A
Kevin M. Snyder, Justyna Sikorska, Tao Ye, Lijing Fang, Wu Su, Rich G. Carter, Kerry L. McPhail and Paul H.-Y. Cheong
DOI: 10.1039/C6OB00707D, Paper


Total synthesis of desoxycyclomarin C and the cyclomarazines A and B
Philipp Barbie and Uli Kazmaier
DOI: 10.1039/C6OB00801A, Paper


Total synthesis of cyclomarins A, C and D, marine cyclic peptides with interesting anti-tuberculosis and anti-malaria activities
Philipp Barbie and Uli Kazmaier
DOI: 10.1039/C6OB00800C, Paper


Total synthesis, biosynthesis and biological profiles of clavine alkaloids
Stephanie R. McCabe and Peter Wipf
DOI:10.1039/C6OB00878J, Review Article


Recent applications in natural product synthesis of dihydrofuran and -pyran formation by ring-closing alkene metathesis
Reece Jacques, Ritashree Pal, Nicholas A. Parker, Claire E. Sear, Peter W. Smith, Aubert Ribaucourt and David M. Hodgson
DOI:10.1039/C6OB00593D, Review Article


We hope you enjoy this selection!
Why not submit your latest natural product research to OBC today?

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Natural Products in OBC

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although signing up to OBC’s e-alert (free service) means you will receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

Abietane diterpenoids from Caryopteris incana (Thunb.) Miq.
Sen-Miao Zhao, Gui-Xin Chou, Qing-Shan Yang, Wei Wang and Jian-Li Zhou
DOI: 10.1039/C6OB00139D, Paper


Multicomponent access to indolo[3,3a-c]isoquinolin-3,6-diones: formal synthesis of (±)-plicamine
Marco V. Mijangos and Luis D. Miranda
DOI: 10.1039/C6OB00231E, Communication


A surprising switch in absolute configuration of anti-inflammatory macrolactones
Johannes Tauber, Markus Rohr, Thorsten Walter, Dieter Schollmeyer, Karin Rahn-Hotze, Gerhard Erkel and Till Opatz
DOI: 10.1039/C6OB00430J, Communication


The total synthesis and functional evaluation of fourteen stereoisomers of yaku’amide B. The importance of stereochemistry for hydrophobicity and cytotoxicity
Hiroyuki Mutoh, Yusuke Sesoko, Takefumi Kuranaga, Hiroaki Itoh and Masayuki Inoue
DOI: 10.1039/C6OB00640J, Communication


Epimerization of C5 of an N-hydroxypyrrolidine in the synthesis of swainsonine related iminosugars
Bao-Chen Qian, Akiko Kamori, Kyoko Kinami, Atsushi Kato, Yi-Xian Li, George W. J. Fleet and Chu-Yi Yu
DOI: 10.1039/C6OB00531D, Paper


Total chemical synthesis of lassomycin and lassomycin-amide
S. Lear, T. Munshi, A. S. Hudson, C. Hatton, J. Clardy, J. A. Mosely, T. J. Bull, C. S. Sit and S. L. Cobb
DOI: 10.1039/C6OB00631K, Paper


ent-Abietane diterpenoids with anti-neuroinflammatory activity from the rare Chloranthaceae plant Chloranthus oldhamii
Juan Xiong, Zhi-Lai Hong, Peng Xu, Yike Zou, Shang-Bo Yu, Guo-Xun Yang and Jin-Feng Hu
DOI: 10.1039/C6OB00731G, Paper


Concise total synthesis of (±)-serotobenine
Kangjiang Liang, Ting Wu and Chengfeng Xia
DOI: 10.1039/C6OB00682E, Paper


Synthesis of substituted tetrahydroisoquinolines by lithiation then electrophilic quench
Ruaa A. Talk, Alexia Duperray, Xiabing Li and Iain Coldham
DOI: 10.1039/C6OB00577B, Paper


Concise synthesis of calystegines B2 and B3via intramolecular Nozaki–Hiyama–Kishi reaction
Hong-Yao Wang, Atsushi Kato, Kyoko Kinami, Yi-Xian Li, George W. J. Fleet and Chu-Yi Yu
DOI: 10.1039/C6OB00697C, Paper


Synthetic investigation toward apigenin 5-O-glycoside camellianin B as well as the chemical structure revision
Yang Hu, Yuan-Hong Tu, De-Yong Liu, Jin-Xi Liao and Jian-Song Sun
DOI: 10.1039/C6OB00655H, Paper


Hydrohalogenative aromatization of multiynes promoted by ruthenium alkylidene complexes
Rajdip Karmakar, Kung-Pern Wang, Sang Young Yun, Phani Mamidipalli and Daesung Lee
DOI: 10.1039/C6OB00524A, Communication


We hope you enjoy this selection!
Why not submit your latest natural product research to OBC today?

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Natural Products in OBC

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although signing up to OBC’s e-alert (free service) means you will receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

Synthesis of new dicinnamoyl 4-deoxy quinic acid and methyl ester derivatives and evaluation of the toxicity against the pea aphid Acyrthosiphon pisum
Xiubin Li, Lucie Grand, Thomas Pouleriguen, Yves Queneau, Pedro da Silva, Yvan Rahbé, Jean-Luc Poëssel and Sylvie Moebs-Sanchez
DOI: 10.1039/C5OB02483H, Paper


Inhibition of HL-60 cell growth via cell cycle arrest and apoptosis induction by a cycloartane–labdane heterodimer from Pseudolarix amabilis
Xinhui Tian, Niao Yang, Bo Li, Jianping Zhang, Xike Xu, Rongcai Yue, Huiliang Li, Liping Chen, Yunheng Shen and Weidong Zhang
DOI: 10.1039/C5OB02661J, Paper


A convenient approach to an advanced intermediate toward the naturally occurring, bioactive 6-substituted 5-hydroxy-4-aryl-1H-quinolin-2-ones
Sebastián O. Simonetti, Enrique L. Larghi and Teodoro S. Kaufman
DOI: 10.1039/C5OB02680F, Paper


Talaroketals A and B, unusual bis(oxaphenalenone) spiro and fused ketals from the soil fungus Talaromyces stipitatus ATCC 10500
Yi Zang, Grégory Genta-Jouve, Pascal Retailleau, Alexandre Escargueil, Stéphane Mann, Bastien Nay and Soizic Prado
DOI: 10.1039/C5OB02657A, Paper


A bio-inspired synthetic route to the core ring systems of Spiraea atisine-type diterpenoid alkaloids and related diterpenes
Dai-Hui Tang, Ding Ma, Hang Cheng, Yong-Li Li and Liang Xu
DOI: 10.1039/C6OB00053C, Paper


Synthesis of rocaglamide derivatives and evaluation of their Wnt signal inhibitory activities
Midori A. Arai, Yuuki Kofuji, Yuuki Tanaka, Natsuki Yanase, Kazuki Yamaku, Rolly G. Fuentes, Utpal Kumar Karmakar and Masami Ishibashi
DOI: 10.1039/C5OB02537K, Paper


Four new carbazole alkaloids from Murraya koenigii that display anti-inflammatory and anti-microbial activities
Yedukondalu Nalli, Vidushi Khajuria, Shilpa Gupta, Palak Arora, Syed Riyaz-Ul-Hassan, Zabeer Ahmed and Asif Ali
DOI: 10.1039/C6OB00267F, Paper


Solution-state conformations of natural products from chiroptical spectroscopy: the case of isocorilagin
R. F. Sprenger, S. S. Thomasi, A. G. Ferreira, Q. B. Cass and J. M. Batista Junior
DOI: 10.1039/C6OB00049E, Paper


A single terpene synthase is responsible for a wide variety of sesquiterpenes in Sorangium cellulosum Soce56
Alexander Schifrin, Yogan Khatri, Philine Kirsch, Verena Thiel, Stefan Schulz and Rita Bernhardt
DOI: 10.1039/C6OB00130K, Paper


Synthesis and absolute configuration assignment of albucidin: a late-stage reductive deiodination by visible light photocatalysis
Hu Zhang, Peng-Fei Liu, Qiong Chen, Qiong-You Wu, Anne Seville, Yu-Cheng Gu, John Clough, Shao-Lin Zhou and Guang-Fu Yang
DOI: 10.1039/C6OB00371K, Paper


We hope you enjoy this selection!
Why not submit your latest natural product research to OBC today?

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Natural Products in OBC

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although signing up to OBC’s e-alert (free service) means you will receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

The chemical synthesis of aryltetralin glycosides
Jian-Song Sun, Hui Liu, Xiao-Hong Guo and Jin-Xi Liao
DOI: 10.1039/C5OB02188J, Review Article


Highly efficient synthesis of flavonol 5-O-glycosides with glycosyl ortho-alkynylbenzoates as donors
Jin-Xi Liao, Nai-Li Fan, Hui Liu, Yuan-Hong Tu and Jian-Song Sun
DOI: 10.1039/C5OB02313K, Communication


Trichiconlides A and B: two novel limonoids from the fruits of Trichilia connaroides
Fa-Liang An, Jun Luo, Xiao-Bing Wang, Ming-Hua Yang and Ling-Yi Kong
Journal Article Org. Biomol. Chem., 2016,14, 1231-1235
DOI: 10.1039/C5OB02300A, Communication


Synthesis of highly enantio-enriched stereoisomers of hydroxy-GR24
J. C. Morris and C. S. P. McErlean
DOI: 10.1039/C5OB02349A, Communication


Divergent synthetic route to new cyclopenta[c]pyran iridoids: syntheses of jatamanin A, F, G and J, gastrolactone and nepetalactone
Jaehoon Sim, Inah Yoon, Hwayoung Yun, Hongchan An and Young-Ger Suh
DOI: 10.1039/C5OB02147B, Paper


Total synthesis of the azolemycins
Zoe J. Anderson and David J. Fox
DOI: 10.1039/C5OB02520F, Paper


Chemoselective room temperature E1cB NN cleavage of oxazolidinone hydrazides from enantioselective aldehyde α-hydrazination: synthesis of (+)-1,4-dideoxyallonojirimycin
Jasmin Ferreira, Sophie C. M. Rees-Jones, Valerie Ramaotsoa, Ath’enkosi Msutu and Roger Hunter
DOI: 10.1039/C5OB02560E, Communication


Marine AChE inhibitors isolated from Geodia barretti: natural compounds and their synthetic analogs
Elisabeth K. Olsen, Espen Hansen, Lindon W. K. Moodie, Johan Isaksson, Kristina Sepčić, Marija Cergolj, Johan Svenson and Jeanette H. Andersen
Journal Article Org. Biomol. Chem., 2016,14, 1629-1640
DOI: 10.1039/C5OB02416A, Paper


Total synthesis and stereochemical revision of xiamenmycin A
Xiaozhen Jiao, Yangyang Yao, Beibei Yang, Xiaoyu Liu, Xiaoyu Li, Hongguang Yang, Li Li, Jun Xu, Minjuan Xu and Ping Xie
DOI: 10.1039/C5OB02476E, Paper


Total synthesis of (±)-epithuriferic acid methyl ester via Diels–Alder reaction
Marek Koprowski, Piotr Bałczewski, Krzysztof Owsianik, Ewa Różycka-Sokołowska and Bernard Marciniak
DOI: 10.1039/C5OB02368H, Paper


Target-specific identification and characterization of the putative gene cluster for brasilinolide biosynthesis revealing the mechanistic insights and combinatorial synthetic utility of 2-deoxy-L-fucose biosynthetic enzymes
Hsien-Tai Chiu, Chien-Pao Weng, Yu-Chin Lin and Kuan-Hung Chen
DOI: 10.1039/C5OB02292D, Paper
From themed collection: 2016 Hot Articles in Organic and Biomolecular Chemistry


Solution-phase synthesis and biological evaluation of triostin A and its analogues
Kozo Hattori, Kota Koike, Kensuke Okuda, Tasuku Hirayama, Masahiro Ebihara, Mei Takenaka and Hideko Nagasawa
DOI: 10.1039/C5OB02505B, Paper


We hope you enjoy this selection!
Why not submit your latest natural product research to OBC today?

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Natural Products in OBC

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although signing up to OBC’s e-alert (free service) means you will receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

Chemical chain termination resolves the timing of ketoreduction in a partially reducing iterative type I polyketide synthase
Hirokazu Kage, Elena Riva, James S. Parascandolo, Martin F. Kreutzer, Manuela Tosin and Markus Nett
DOI: 10.1039/C5OB02009C, Communication


The biosynthesis of allelopathic di-C-glycosylflavones from the roots of Desmodium incanum (G. Mey.) DC
Bing Hao, John C. Caulfield, Mary L. Hamilton, John A. Pickett, Charles A. O. Midega, Zeyaur R. Khan, Junru R. Wang and Antony M. Hooper
DOI: 10.1039/C5OB01926E, Paper


A novel C,D-spirodioxene taxoid synthesized through an unexpected Pd-mediated ring cyclization
Shao-Rong Wang, Pedro A. Sánchez-Murcia, Federico Gago and Wei-Shuo Fang
DOI: 10.1039/C5OB02131F, Paper


Total synthesis of a piperidine alkaloid, microcosamine A
Chada Raji Reddy, Bellamkonda Latha, Kamalkishor Warudikar and Kiran Kumar Singarapu
DOI: 10.1039/C5OB02085A, Paper


The structure of tagetitoxin
Abil E. Aliev, Kersti Karu, Robin E. Mitchell and Michael J. Porter
DOI: 10.1039/C5OB02076J, Paper


Total synthesis and preliminary SAR study of (±)-merochlorins A and B
Hongzhi Yang, Xue Liu, Qingong Li, Longbo Li, Jing-Ren Zhang and Yefeng Tang
DOI: 10.1039/C5OB01946J, Paper
From themed collection 2016 Hot Articles in Organic and Biomolecular Chemistry


A method for investigating the stereochemical course of terpene cyclisations
Patrick Rabe, Jan Rinkel, Tim A. Klapschinski, Lena Barra and Jeroen S. Dickschat
DOI: 10.1039/C5OB01998B, Paper


Stereoselective total synthesis of (−)-nupharamine utilizing an α-chlorosulfide and a sulfinimine for C–C bond formation
Sadagopan Raghavan and Sheelamanthula Rajendar
DOI: 10.1039/C5OB01750E, Paper


Antimalarial diterpenoid dimers of a new carbon skeleton from Aphanamixis grandifolia
Hua Zhang, Jia Liu, Li-She Gan, Seema Dalal, Maria B. Cassera and Jian-Min Yue
DOI: 10.1039/C5OB02296G, Paper


Chemical constituents of the soft corals Sinularia vanderlandi and Sinularia gravis from the coast of Madagascar
Marie Pascaline Rahelivao, Margit Gruner, Tilo Lübken, Daut Islamov, Olga Kataeva, Hanta Andriamanantoanina, Ingmar Bauer and Hans-Joachim Knölker
DOI: 10.1039/C5OB02280K, Paper
From themed collection 2016 Hot Articles in Organic and Biomolecular Chemistry


We hope you enjoy this selection!
Why not submit your latest natural product research to OBC today?

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