Author Archive

Natural Products in OBC

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although signing up to OBC’s e-alert (free service) means you will receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

Synthesis of monoalkylidene diketopiperazines and application to the synthesis of barettin
Elizabeth W. Kelley, Skylar G. Norman and Jonathan R. Scheerer
DOI: 10.1039/C7OB02297B

Stereocontrolled synthesis and investigation of the biosynthetic transformations of 16(S),17(S)-epoxy-PDn-3 DPA
Karoline Gangestad Primdahl, Jørn Eivind Tungen, Patricia Regina Soares De Souza, Romain Alexandre Colas, Jesmond Dalli, Trond Vidar Hansen and Anders Vik
DOI: 10.1039/C7OB02113E

Total synthesis of (−)-aritasone via the ultra-high pressure hetero-Diels–Alder dimerisation of (−)-pinocarvone
Maliha Uroos, Phillip Pitt, Laurence M. Harwood, William Lewis, Alexander J. Blake and Christopher J. Hayes
DOI: 10.1039/C7OB02204B

Unprecedented 22,26-seco physalins from Physalis angulata and their anti-inflammatory potential
Cheng-Peng Sun, Mahmood Brobbey Oppong, Feng Zhao, Li-Xia Chen and Feng Qiu
DOI: 10.1039/C7OB02205K

Doubling the power of DP4 for computational structure elucidation
K. Ermanis, K. E. B. Parkes, T. Agbackb and J. M. Goodman
DOI: 10.1039/C7OB01379E

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Natural Products in OBC

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although signing up to OBC’s e-alert (free service) means you will receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

Insights into the role of 3-O-sulfotransferase in heparan sulfate biosynthesis
Maria Cecília Zorél Meneghetti, Tarsis Gesteira Ferreira, Alexandre Keiji Tashima, Suely F. Chavante, Edwin Alexander Yates, Jian Liu, Helena Bonciani Nader and Marcelo A. Lima
DOI: 10.1039/C7OB01533J, Paper


A synthetic dodecanolide library for the identification of putative semiochemicals emitted by mantellid frogs
Pardha Saradhi Peram, Miguel Vences and Stefan Schulz
DOI: 10.1039/C7OB00849J, Paper


Forsythenethosides A and B: two new phenylethanoid glycosides with a 15-membered ring from Forsythia suspensa
Si-Yuan Shao, Zi-Ming Feng, Ya-Nan Yang, Jian-Shuang Jiang and Pei-Cheng Zhang
DOI: 10.1039/C7OB01811H, Paper


Total syntheses of gerberinol I and the pterophyllins 2 and 4 using the Casnati–Skattebøl reaction under different conditions
Jorgelina L. Pergomet, Andrea B. J. Bracca and Teodoro S. Kaufman
DOI: 10.1039/C7OB01471F, Paper


Volatiles from the fungal microbiome of the marine sponge Callyspongia cf flammea
Lena Barra, Paul Barac, Gabriele M. König, Max Crüsemann and Jeroen S. Dickschat
DOI: 10.1039/C7OB01837A, Paper


Selective lysine modification of native peptides via aza-Michael addition
Hongli Chen, Rong Huang, Zhihong Li, Wei Zhu, Jiakang Chen, Yuexiong Zhan and Biao Jiang
DOI:10.1039/C7OB01866E, Paper


Synthesis of the fungus metabolite cladosin C
David Linder and Rainer Schobert
DOI:10.1039/C7OB01795B, Paper


18 O2 labeling experiments illuminate the oxidation of ent-kaurene in bacterial gibberellin biosynthesis
Raimund Nagel and Reuben J. Peters
DOI:10.1039/C7OB01819C, Paper


Modular total syntheses of mycolactone A/B and its [2H]-isotopologue
Sarah Saint-Auret, Hajer Abdelkafi, Didier Le Nouen, Laure Guenin-Macé, Caroline Demangel, Philippe Bisseret and Nicolas Blanchard
DOI: 10.1039/C7OB01943B, Communication


A bifunctional old yellow enzyme from Penicillium roqueforti is involved in ergot alkaloid biosynthesis
Nina Gerhards and Shu-Ming Li
DOI: 10.1039/C7OB02095C


Incorporation of [2H1]-(1R,2R)- and [2H1]-(1S,2R)-glycerols into the antibiotic nucleocidin in Streptomyces calvus
Xuan Feng, Nawaf Al Maharik, Axel Bartholomé, Jeffrey E. Janso, Usa Reilly and David O’Hagan
DOI: 10.1039/C7OB02163A


Nazarov reaction: current trends and recent advances in the synthesis of natural compounds and their analogs
Maxim G. Vinogradov, Olga V. Turova and Sergei G. Zlotin
DOI: 10.1039/C7OB01981E

 

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What are you colleagues reading in Natural Product Reports?

The articles below are some of the most read Natural Product Reports articles in April, May and June 2017.

Fragmentation reactions using electrospray ionization mass spectrometry: an important tool for the structural elucidation and characterization of synthetic and natural products
Daniel P. Demarque, Antonio E. M. Crotti, Ricardo Vessecchi, João L. C. Lopes and Norberto P. Lopes
DOI: 10.1039/C5NP00073D

Monomer design strategies to create natural product-based polymer materials
Samantha L. Kristufek, Kevin T. Wacker, Yi-Yun Timothy Tsao, Lu Su and Karen L. Wooley
DOI: 10.1039/C6NP00112B

Marine natural products (2017)
John W. Blunt, Brent R. Copp, Robert A. Keyzers, Murray H. G. Munro and Michèle R. Prinsep
DOI: 10.1039/C6NP00124F

The evolution of genome mining in microbes – a review
Nadine Ziemert, Mohammad Alanjary and Tilmann Weber
DOI: 10.1039/C6NP00025H

Recent advances in engineering nonribosomal peptide assembly lines
M. Winn, J. K. Fyans, Y. Zhuo and J. Micklefield
DOI: 10.1039/C5NP00099H

Chemical proteomics approaches for identifying the cellular targets of natural products
M. H. Wright and S. A. Sieber
DOI: 10.1039/C6NP00001K

Metabolomics in chemical ecology
Constanze Kuhlisch and Georg Pohnert
DOI: 10.1039/C5NP00003C

Phytocannabinoids: a unified critical inventory
Lumír Ondřej Hanuš, Stefan Martin Meyer, Eduardo Muñoz, Orazio Taglialatela-Scafati and Giovanni Appendino
DOI: 10.1039/C6NP00074F

Recent advances in research on lignans and neolignans
Rémy Bertrand Teponno, Souvik Kusari and Michael Spiteller
DOI: 10.1039/C6NP00021E

Marine natural products (2016)
John W. Blunt, Brent R. Copp, Robert A. Keyzers, Murray H. G. Munro and Michèle R. Prinsep
DOI: 10.1039/C5NP00156K

Defensive symbioses of animals with prokaryotic and eukaryotic microorganisms
Laura V. Flórez, Peter H. W. Biedermann, Tobias Engl and Martin Kaltenpoth
DOI: 10.1039/C5NP00010F

Ester coupling reactions – an enduring challenge in the chemical synthesis of bioactive natural products
Michail Tsakos, Eva S. Schaffert, Lise L. Clement, Nikolaj L. Villadsen and Thomas B. Poulsen
DOI: 10.1039/C4NP00106K

Synthetic approaches towards alkaloids bearing α-tertiary amines
Anastasia Hager, Nina Vrielink, Dominik Hager, Julien Lefranc and Dirk Trauner
DOI: 10.1039/C5NP00096C

Recent advances in the field of bioactive tetronates
Laura Vieweg, Sebastian Reichau, Rainer Schobert, Peter F. Leadlay and Roderich D. Süssmuth
DOI: 10.1039/C4NP00015C

A tale of four kingdoms – isoxazolin-5-one- and 3-nitropropanoic acid-derived natural products
Tobias Becker, Jacques Pasteels, Christiane Weigel, Hans-Martin Dahse, Kerstin Voigt and Wilhelm Boland
DOI: 10.1039/C6NP00122J

Keep up-to-date with the latest issues of Natural Product Reports with our E-alerts

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Natural Products in OBC

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although signing up to OBC’s e-alert (free service) means you will receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

Carpatizine, a novel bridged oxazine derivative generated by non-enzymatic reactions
Peng Fu and John B. MacMillan
DOI: 10.1039/C7OB01178D, Communication


The formation of sesquiterpenoid presilphiperfolane and cameroonane metabolites in the Bcbot4 null mutant of Botrytis cinerea
Gabriel Franco dos Santos, Javier Moraga, Jacqueline A. Takahashi, Muriel Viaud, James R. Hanson, Rosario Hernández Galán and Isidro G. Collado
DOI: 10.1039/C7OB01088E, Paper


Isolation and identification of L/D-lactate-conjugated bufadienolides from toad eggs revealing lactate racemization in amphibians
Shiwen Zhou, Qingfei Zheng, Xiuyong Huang, Yong Wang, Sifan Luo, Renwang Jiang, Lei Wang, Wencai Ye and Haiyan Tian
DOI: 10.1039/C7OB01055A, Paper


Sophopterocarpan A, a novel pterocarpine derivative with a benzotetrahydrofuran-fused bicyclo [3.3.1] nonane from Sophora flavescens
Hui Zhu, Ya-Nan Yang, Kuo Xu, Jing Xie, Zi-Ming Feng, Jian-Shuang Jiang and Pei-Cheng Zhang
DOI: 10.1039/C7OB01261F, Communication


Enzymatic competition and cooperation branch the caerulomycin biosynthetic pathway toward different 2,2′-bipyridine members
Ming Chen, Yipeng Zhang, Yanan Du, Qunfei Zhao, Qinglin Zhang, Jiequn Wu and Wen Liu
DOI: 10.1039/C7OB01284E, Communication


Formal total synthesis of selaginpulvilin D
Bhavani Shankar Chinta and Beeraiah Baire
DOI: 10.1039/C7OB00950J, Paper


Strategy towards the enantioselective synthesis of schiglautone A
Camille Le Chapelain
DOI: 10.1039/C7OB00766C, Paper


Synthesis and biological evaluation of the ascidian blood-pigment halocyamine A
Hugo K. H. Fong, Jean Michel Brunel, Arlette Longeon, Marie-Lise Bourguet-Kondracki, David Barker and Brent R. Copp
DOI: 10.1039/C7OB01122A, Paper


A practical approach to asymmetric synthesis of dolastatin 10
Wen Zhou, Xiao-Di Nie, Yu Zhang, Chang-Mei Si, Zhu Zhou, Xun Sun and Bang-Guo Wei
DOI: 10.1039/C7OB01395G, Paper

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Natural Products in OBC

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although signing up to OBC’s e-alert (free service) means you will receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

First total synthesis of (+)-broussonetine W: glycosidase inhibition of natural product & analogs
Ying-Ying Song, Kyoko Kinami, Atsushi Kato, Yue-Mei Jia, Yi-Xian Li, George W. J. Fleet and Chu-Yi Yu
DOI: 10.1039/C6OB00720A, Paper


Synthesis of a simplified triazole analogue of pateamine A
A. Hemi Cumming, Sarah L. Brown, Xu Tao, Claire Cuyamendous, Jessica J. Field, John H. Miller, Joanne E. Harvey and Paul H. Teesdale-Spittle
DOI: 10.1039/C6OB00086J, Paper


Studies towards the synthesis of tedanolide C. Construction of the C13-epi C1–C15 fragment
Joana Zambrana, Pedro Romea and Fèlix Urpí
DOI: 10.1039/C6OB00896H, Communication


Asymmetric synthesis of crambescin A–C carboxylic acids and their inhibitory activity on voltage-gated sodium channels
Atsuo Nakazaki, Yoshiki Nakane, Yuki Ishikawa, Mari Yotsu-Yamashita and Toshio Nishikawa
DOI: 10.1039/C6OB00914J, Paper


Nitropyrrole natural products: isolation, biosynthesis and total synthesis
Xiao-Bo Ding, Margaret A. Brimble and Daniel P. Furkert
DOI: 10.1039/C5OB02599K, Review Article


Some chemical speculation on the biosynthesis of corallidictyals A–D
Adrian W. Markwell-Heys and Jonathan H. George
DOI: 10.1039/C6OB00171H, Communication


First total synthesis of trehalose containing tetrasaccharides from Mycobacterium smegmatis
Manishkumar A. Chaube, Vikram A. Sarpe, Santanu Jana and Suvarn S. Kulkarni
DOI: 10.1039/C6OB00412A, Communication


Towards theory driven structure elucidation of complex natural products: mandelalides and coibamide A
Kevin M. Snyder, Justyna Sikorska, Tao Ye, Lijing Fang, Wu Su, Rich G. Carter, Kerry L. McPhail and Paul H.-Y. Cheong
DOI: 10.1039/C6OB00707D, Paper


Total synthesis of desoxycyclomarin C and the cyclomarazines A and B
Philipp Barbie and Uli Kazmaier
DOI: 10.1039/C6OB00801A, Paper


Total synthesis of cyclomarins A, C and D, marine cyclic peptides with interesting anti-tuberculosis and anti-malaria activities
Philipp Barbie and Uli Kazmaier
DOI: 10.1039/C6OB00800C, Paper


Total synthesis, biosynthesis and biological profiles of clavine alkaloids
Stephanie R. McCabe and Peter Wipf
DOI:10.1039/C6OB00878J, Review Article


Recent applications in natural product synthesis of dihydrofuran and -pyran formation by ring-closing alkene metathesis
Reece Jacques, Ritashree Pal, Nicholas A. Parker, Claire E. Sear, Peter W. Smith, Aubert Ribaucourt and David M. Hodgson
DOI:10.1039/C6OB00593D, Review Article


We hope you enjoy this selection!
Why not submit your latest natural product research to OBC today?

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Natural Products in OBC

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although signing up to OBC’s e-alert (free service) means you will receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

Abietane diterpenoids from Caryopteris incana (Thunb.) Miq.
Sen-Miao Zhao, Gui-Xin Chou, Qing-Shan Yang, Wei Wang and Jian-Li Zhou
DOI: 10.1039/C6OB00139D, Paper


Multicomponent access to indolo[3,3a-c]isoquinolin-3,6-diones: formal synthesis of (±)-plicamine
Marco V. Mijangos and Luis D. Miranda
DOI: 10.1039/C6OB00231E, Communication


A surprising switch in absolute configuration of anti-inflammatory macrolactones
Johannes Tauber, Markus Rohr, Thorsten Walter, Dieter Schollmeyer, Karin Rahn-Hotze, Gerhard Erkel and Till Opatz
DOI: 10.1039/C6OB00430J, Communication


The total synthesis and functional evaluation of fourteen stereoisomers of yaku’amide B. The importance of stereochemistry for hydrophobicity and cytotoxicity
Hiroyuki Mutoh, Yusuke Sesoko, Takefumi Kuranaga, Hiroaki Itoh and Masayuki Inoue
DOI: 10.1039/C6OB00640J, Communication


Epimerization of C5 of an N-hydroxypyrrolidine in the synthesis of swainsonine related iminosugars
Bao-Chen Qian, Akiko Kamori, Kyoko Kinami, Atsushi Kato, Yi-Xian Li, George W. J. Fleet and Chu-Yi Yu
DOI: 10.1039/C6OB00531D, Paper


Total chemical synthesis of lassomycin and lassomycin-amide
S. Lear, T. Munshi, A. S. Hudson, C. Hatton, J. Clardy, J. A. Mosely, T. J. Bull, C. S. Sit and S. L. Cobb
DOI: 10.1039/C6OB00631K, Paper


ent-Abietane diterpenoids with anti-neuroinflammatory activity from the rare Chloranthaceae plant Chloranthus oldhamii
Juan Xiong, Zhi-Lai Hong, Peng Xu, Yike Zou, Shang-Bo Yu, Guo-Xun Yang and Jin-Feng Hu
DOI: 10.1039/C6OB00731G, Paper


Concise total synthesis of (±)-serotobenine
Kangjiang Liang, Ting Wu and Chengfeng Xia
DOI: 10.1039/C6OB00682E, Paper


Synthesis of substituted tetrahydroisoquinolines by lithiation then electrophilic quench
Ruaa A. Talk, Alexia Duperray, Xiabing Li and Iain Coldham
DOI: 10.1039/C6OB00577B, Paper


Concise synthesis of calystegines B2 and B3via intramolecular Nozaki–Hiyama–Kishi reaction
Hong-Yao Wang, Atsushi Kato, Kyoko Kinami, Yi-Xian Li, George W. J. Fleet and Chu-Yi Yu
DOI: 10.1039/C6OB00697C, Paper


Synthetic investigation toward apigenin 5-O-glycoside camellianin B as well as the chemical structure revision
Yang Hu, Yuan-Hong Tu, De-Yong Liu, Jin-Xi Liao and Jian-Song Sun
DOI: 10.1039/C6OB00655H, Paper


Hydrohalogenative aromatization of multiynes promoted by ruthenium alkylidene complexes
Rajdip Karmakar, Kung-Pern Wang, Sang Young Yun, Phani Mamidipalli and Daesung Lee
DOI: 10.1039/C6OB00524A, Communication


We hope you enjoy this selection!
Why not submit your latest natural product research to OBC today?

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What are your colleagues reading in Natural Product Reports?

The articles below are some of the most read Natural Product Reports articles in January, February and March 2016.

Franz Bucar, Abraham Wube and Martin Schmid
DOI: 10.1039/C3NP20106F, Review Article

Marine natural products
John W. Blunt, Brent R. Copp, Robert A. Keyzers, Murray H. G. Munro and Michèle R. Prinsep
DOI: 10.1039/C5NP00156K, Review Article

Metabolomics in chemical ecology
Constanze Kuhlisch and Georg Pohnert
DOI: 10.1039/C5NP00003C, Review Article

Defensive symbioses of animals with prokaryotic and eukaryotic microorganisms
Laura V. Flórez, Peter H. W. Biedermann, Tobias Engl and Martin Kaltenpoth
DOI: 10.1039/C5NP00010F, Review Article

Biosynthesis of fungal meroterpenoids
Yudai Matsuda and Ikuro Abe
DOI: 10.1039/C5NP00090D, Review Article

Marine natural products
John W. Blunt, Brent R. Copp, Robert A. Keyzers, Murray H. G. Munro and Michèle R. Prinsep
DOI: 10.1039/C4NP00144C, Review Article

Prospecting for new bacterial metabolites: a glossary of approaches for inducing, activating and upregulating the biosynthesis of bacterial cryptic or silent natural products
Joseph Scott Zarins-Tutt, Tania Triscari Barberi, Hong Gao, Andrew Mearns-Spragg, Lixin Zhang, David J. Newman and Rebecca Jane Miriam Goss
DOI: 10.1039/C5NP00111K, Review Article

Recent advances in engineering nonribosomal peptide assembly lines
M. Winn, J. K. Fyans, Y. Zhuo and J. Micklefield
DOI: 10.1039/C5NP00099H, Review Article

Mass spectrometry imaging of plant metabolites – principles and possibilities
Nanna Bjarnholt, Bin Li, Janina D’Alvise and Christian Janfelt
DOI: 10.1039/C3NP70100J, Review Article

Ester coupling reactions – an enduring challenge in the chemical synthesis of bioactive natural products
Michail Tsakos, Eva S. Schaffert, Lise L. Clement, Nikolaj L. Villadsen and Thomas B. Poulsen
DOI: 10.1039/C4NP00106K, Review Article

Bacterial terpene cyclases
Jeroen S. Dickschat
DOI: 10.1039/C5NP00102A, Review Article

Natural product and natural product derived drugs in clinical trials
Mark S. Butler, Avril A. B. Robertson and Matthew A. Cooper
DOI: 10.1039/C4NP00064A, Review Article

Don’t forget to take a look at our recent themed issues on:
Biosynthetic Assembly Lines
Strategies for Cellular Target Identification of Natural Products

Keep up-to-date with the latest issues of Natural Product Reports with our E-alerts

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Balticum Organicum Syntheticum (BOS) conference 2016

Balticum Organicum Syntheticum (BOS) conference 2016

3rd – 6th July 2016, Riga, Latvia

Natural Product Reports and Organic & Biomolecular Chemistry are pleased to support the 2016 BOS conference.  The conference aims to provide a forum for organic synthetic chemists to speak of their work and discuss important scientific problems and to promote discussion between academic and industrial scientists about the possibilities of mutual cooperation.

This international conference has a balanced program of academic and industrial speakers presenting fundamental and practical aspects of organic synthesis.  This year the speakers include:

  • Emily Balskus (Harvard University, USA) Chemical Discovery in the Microbial World
  • Inga Cikotiené (Vilnius University, Lithuania) From Curiosity to Development of New Synthetic Methods
  • Nuno Maulide (University of Vienna, Austria) Catalytic Rearrangements: Inspiration for Methods and Total Synthesis
  • Per-Ola Norrby (AstraZeneca, Sweden) Predictive Chemistry: Virtual Screening in Asymmetric Catalysis
  • Virgil Percec (University of Pennsylvania, USA) A Materials Genome Approach to Mimics of Biological Membranes and their Programmable Glycan Ligands
  • Stefan Schunk (Grünenthal GmbH, Germany) Cebranopadol, A Novel Analgesic – It’s Discovery from the MedChem Perspective
  • Ryan Shenvi (The Scripps Research Institute) Chemical Synthesis of Secondary Metabolites
  • John Sutherland (MRC Laboratory of Molecular Biology, Cambridge UK) Origins of Life Systems Chemistry
  • Māris Turks (Riga Technical University, Latvia) Sulfer Dioxide: Useful Reagent and Solvent in Organic Chemistry

For more information and to register please visit the website.

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Natural Products in OBC

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although signing up to OBC’s e-alert (free service) means you will receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

Synthesis of new dicinnamoyl 4-deoxy quinic acid and methyl ester derivatives and evaluation of the toxicity against the pea aphid Acyrthosiphon pisum
Xiubin Li, Lucie Grand, Thomas Pouleriguen, Yves Queneau, Pedro da Silva, Yvan Rahbé, Jean-Luc Poëssel and Sylvie Moebs-Sanchez
DOI: 10.1039/C5OB02483H, Paper


Inhibition of HL-60 cell growth via cell cycle arrest and apoptosis induction by a cycloartane–labdane heterodimer from Pseudolarix amabilis
Xinhui Tian, Niao Yang, Bo Li, Jianping Zhang, Xike Xu, Rongcai Yue, Huiliang Li, Liping Chen, Yunheng Shen and Weidong Zhang
DOI: 10.1039/C5OB02661J, Paper


A convenient approach to an advanced intermediate toward the naturally occurring, bioactive 6-substituted 5-hydroxy-4-aryl-1H-quinolin-2-ones
Sebastián O. Simonetti, Enrique L. Larghi and Teodoro S. Kaufman
DOI: 10.1039/C5OB02680F, Paper


Talaroketals A and B, unusual bis(oxaphenalenone) spiro and fused ketals from the soil fungus Talaromyces stipitatus ATCC 10500
Yi Zang, Grégory Genta-Jouve, Pascal Retailleau, Alexandre Escargueil, Stéphane Mann, Bastien Nay and Soizic Prado
DOI: 10.1039/C5OB02657A, Paper


A bio-inspired synthetic route to the core ring systems of Spiraea atisine-type diterpenoid alkaloids and related diterpenes
Dai-Hui Tang, Ding Ma, Hang Cheng, Yong-Li Li and Liang Xu
DOI: 10.1039/C6OB00053C, Paper


Synthesis of rocaglamide derivatives and evaluation of their Wnt signal inhibitory activities
Midori A. Arai, Yuuki Kofuji, Yuuki Tanaka, Natsuki Yanase, Kazuki Yamaku, Rolly G. Fuentes, Utpal Kumar Karmakar and Masami Ishibashi
DOI: 10.1039/C5OB02537K, Paper


Four new carbazole alkaloids from Murraya koenigii that display anti-inflammatory and anti-microbial activities
Yedukondalu Nalli, Vidushi Khajuria, Shilpa Gupta, Palak Arora, Syed Riyaz-Ul-Hassan, Zabeer Ahmed and Asif Ali
DOI: 10.1039/C6OB00267F, Paper


Solution-state conformations of natural products from chiroptical spectroscopy: the case of isocorilagin
R. F. Sprenger, S. S. Thomasi, A. G. Ferreira, Q. B. Cass and J. M. Batista Junior
DOI: 10.1039/C6OB00049E, Paper


A single terpene synthase is responsible for a wide variety of sesquiterpenes in Sorangium cellulosum Soce56
Alexander Schifrin, Yogan Khatri, Philine Kirsch, Verena Thiel, Stefan Schulz and Rita Bernhardt
DOI: 10.1039/C6OB00130K, Paper


Synthesis and absolute configuration assignment of albucidin: a late-stage reductive deiodination by visible light photocatalysis
Hu Zhang, Peng-Fei Liu, Qiong Chen, Qiong-You Wu, Anne Seville, Yu-Cheng Gu, John Clough, Shao-Lin Zhou and Guang-Fu Yang
DOI: 10.1039/C6OB00371K, Paper


We hope you enjoy this selection!
Why not submit your latest natural product research to OBC today?

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New Editorial Board Members

We are very pleased to welcome two new members to our Natural Product Reports Editorial Board. Professor Janet Smith (University of Michigan, USA) and Dr Olga Genilloud (Fundación MEDINA, Spain).

Professor Janet Smith obtained her PhD in Biochemistry from the University of Wisconsin-Madison in 1978. After postdoctoral studies at the Naval Research Laboratory, she was an associate research scientist at Columbia University.  Professor Smith moved to Purdue University and established a research program in structural biology in 1987, where she remained as Professor of Biological Sciences until moving to the Life Science Institute, University of Michigan, in 2005. She is currently Margaret J. Hunter Collegiate Professor in the Life Sciences, Professor of Biological Chemistry and Director of the Centre for Structural Biology at University of Michigan.

Her research focuses on:

  • Understanding protein structure and function using X-ray crystallography as a structural tool
  • Examining the structures of proteins from infectious pathogens including the RNA viruses that cause West Nile disease, yellow fever, and dengue hemorrhagic fever
  • Understanding the operation of biosynthetic assembly lines for natural products and the activity and selectivity of enzymes that catalyse unusual reactions in natural product biosynthesis

Dr Olga Genilloud obtained her PhD in Biochemistry and Molecular Genetics from the Universidad Complutense de Madrid in 1988. Following this she joined the Drug Discovery Research Center at Merck Sharp and Dohme in Spain were she led the bacterial natural products program. In 2009 she was appointed Scientific Director at Fundación MEDINA and Head of the Microbiology department.

Her main research interests are focused on:

  • The production of novel microbial natural products
  • The exploration of novel microbial diversity to deliver novel chemistry
  • The development of molecular and chemical tools to support natural products drug discovery and the identification of potential new therapeutics

Find out more about the other members of our Editorial and Advisory Boards here.

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