Author Archive

New Editorial Board Members for Natural Product Reports

We are very pleased to welcome two new members to our Editorial Board this month: Professor Julia Kubanek (Georgia Institute of Technology, USA) and Professor Wen Liu (Shanghai Institute of Organic Chemistry, China).


Professor Julia Kubanek

Prof. Kubanek received her Ph.D. in Organic Chemistry in 1998 from the University of British Columbia. Following this she held postdoctoral positions at the Scripps Institution of Oceanography, University California San Diego (1998–2000) and the University of North Carolina at Wilmington (2000–2001). In 2001 she joined the Georgia Institute of Technology becoming a Professor in 2011.

Her current areas of interest include:

Aquatic chemical ecology; Chemical signaling; Chemical communication; Marine natural products chemistry; Chemical biology; Secondary metabolism; Drug discovery; Plankton ecology; Metabolomics

I’ve been reading Natural Product Reports since I was a graduate student in the early 1990’s. I’m pleased to join the NPR family as a member of the Editorial Board and looking forward to working with authors to bring important research to the attention of the natural products chemistry community.” Prof. Julia Kubanek



Professor Wen Liu

Prof. Wen Liu obtained his Ph.D. degree from the Chinese Academy of Medical Sciences (Peking Union Medical School) in 2000. After postdoctoral studies at the Department of Chemistry, University of California, Davis (2000-2001), and the School of Pharmacy, University of Wisconsin-Madison (2001-2003), he joined the Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences in 2003.

His research interests focus on:
1) natural product biosynthesis (genetics, biochemistry and chemistry)
2) combinatorial biosynthesis for production improvement and structural diversity
3) genome and/or transcriptome mining for discovery of novel microbial natural products

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Natural Product Reports at conferences in 2014

Dr Marie Cote, Deputy Editor

Dr Richard Kelly, Managing Editor

The Natural Product Reports team will be attending a number of conferences in 2014 and we would be delighted to meet you there.

We’re also the team behind Natural Product Reports’ sister journals Organic & Biomolecular Chemistry, MedChemComm, and the latest addition to the portfolio, Toxicology Research, so we’ll happily discuss your interdisciplinary research work. In fact, many of our authors choose to publish their research across all of these titles.

Here are just some of the conferences where you can meet us in the coming months:


GRC marine natural products 2-7 March Ventura, CA, USA – Meet Rich

Society of Toxicology annual meeting 23-27 March Phoenix, USA – Meet Marie

National Organic Symposium Trust 11-14 April Agra, India – Meet Rich

ISMSC-9 7-11 June Shanghai, China – Meet Marie

GRC Bioorganic Chemistry 8-13 June Proctor Academy, USA – Meet Rich

BOSS XIV 13-18 July Louvain-la-Neuve, Belgium – Meet Marie

Fall ACS meeting 10-14 August San Francisco, USA – Meet Rich

Gregynog Young Chemists’ Workshop 10-12 September Gregynog, Wales – Meet Marie

EFMC-ISMC 7-10 September Lisbon, Portugal – Meet Rich

Eurotox 7-9 September Edinburgh, UK – Meet Marie

 

Let us know if you are planning on attending any of these meetings, as we would be happy to meet you there!

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RSC Organic Division Poster Symposium: Deadline for poster abstracts 02 October 2013

RSC Organic Division Poster Symposium: Deadline for poster abstracts 02 October 2013

The RSC Organic Division Poster Symposium is still accepting abstracts, but not for long. If you are a final year PhD student based in the UK/ROI and would like the opportunity to showcase your work to leading chemists in industry and academia, as well as your peers, make sure you submit your poster abstract by Wednesday 2nd October.

The symposium will take place on Monday 2nd December 2013, at The Chemistry Centre, Burlington House, London and there are several prizes available on the day. Alongside the £500 First Prize, there will also be a £500 “Selected by Industry” prize and two runners-up prizes of £250. And this year our headline sponsor,  F. Hoffmann-La Roche are offering a further prize of a visit to their site in Basel, Switzerland, to the First and Industry prize winners.

Reasonable travel costs will be covered for the students who are selected to present at this meeting. If you would like to find out more about the symposium and submit an abstract, visit our symposium website

We would like to thank F. Hoffmann-La Roche, Ltd. for their generous support of this event.

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Ribosomally synthesised natural products: a new name for a new year

A large collection of leading researchers in the field of natural product synthesis have come together to propose a communal nomenclature system for the biosynthesis of ribosomally synthesised and posttranslationally modified peptides (RiPPs).

The number of ribosomally synthesised natural products is rapidly increasing, and currently there is no uniform nomenclature being applied across the different compound classes. The classifications currently being used are starting to break down with the increasing number of available genome sequences; the nomenclature used in the various communities investigating subgroups of natural products of ribosomal origin can be confusing, and in some cases even contradictory.

Following on from several discussion groups, the authors of this review (who are working on different classes of RiPPs) present recommendations for a common nomenclature that encompasses all classes, and hope that such a nomenclature will be supported by the rest of the community with the classification of new classes.

In addition to this nomenclature recommendation the authors also present an overview of the current knowledge of the structures and biosynthesis of more than twenty distinct compound classes with examples from bacteria, plants and fungi.

Read this highly informative review today and help sculpt and direct the future of RiPP research.

Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature
DOI: 10.1039/C2NP20085F

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ICPOC21: poster abstracts

There is still just time to submit your poster abstract to the 21st IUPAC International Conference on Physical Organic Chemistry (ICPOC 21) but don’t delay as the deadline is 13 July.

Register early for the best prices.

Why join ICPOC21?

Professor Dean Tantillo, University of California, Davis (USA) is the winner of the 2011 NPR Lecture Award and will be delivering his lecture at ICPOC 21.

The NPR Lecture Award is awarded to a researcher who has made a significant contribution to the field of natural products and who has been involved with the journal. Professor Tantillo was selected for his work in the field of enzymology.

In addition to the outstanding plenary sessions, there will be three parallel sessions over the five days comprising invited lectures and contributed talks, as well as poster sessions.

A broad range of scientists from across the whole community who share a quantitative perspective on chemistry will be there, providing an opportunity to discuss and celebrate the current status, development, and the future of physical organic chemistry.

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2011 Impact Factor for OBC, MedChemComm & NPR

The 2011 Journal Citation Reports ® (Thomson Reuters, 2012) have just been released, which showed:

Organic & Biomolecular Chemistry: 3.696

MedChemComm: 2.8         (Partial IF only, based on five issues)

Natural Product Reports: 9.79

The Cambridge Editorial Office would like to thank everyone involved for their hard work and dedication to all three journals over the years. In particular, we would like to thank all of our Associate Editors, Editorial and Advisory Board members, authors and referees, without whom none of this would have been possible.

With another successful year in the bag, we hope you will join us in making this year even better…

Read more about the 2011 Impact Factors from across RSC Publishing on the RSC Publishing Blog.

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Natural products in OBC

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although your best bet is for you to sign up to OBC’s e-alert (free service), and receive the tables of content directly in your inbox every time an issue is published.

The latest natural products’ related articles have been collated here:

First total synthesis of (+)-indicanone
Yujiro Hayashi, Kumiko Ogawa, Fuyuhiko Inagaki and Chisato Mukai
Org. Biomol. Chem., 2012, 10, 4747-4751
DOI: 10.1039/C2OB25500F, Paper

Synthesis of the trans-hydrindane core of dictyoxetane
Benedicte Defaut, Thomas B. Parsons, Neil Spencer, Louise Male, Benson M. Kariuki and Richard S. Grainger
Org. Biomol. Chem., 2012, 10, 4926-4932
DOI: 10.1039/C2OB25384D, Paper

A novel C,D-spirolactone analogue of paclitaxel: autophagy instead of apoptosis as a previously unknown mechanism of cytotoxic action for taxoids
Milena V. Trmcic, Radomir V. Matovic, Gordana I. Tovilovic, Biljana Z. Ristic, Vladimir S. Trajkovic, Zorana B. Ferjancic and Radomir N. Saicic
Org. Biomol. Chem., 2012, 10, 4933-4942
DOI: 10.1039/C2OB25514F, Paper

Rubesanolides C–E: abietane diterpenoids isolated from Isodon rubescens and evaluation of their anti-biofilm activity
Juan Zou, Lutai Pan, Qiji Li, Jianxin Pu, Ping Yao, Min Zhu, Jeffrey A. Banas, Hongjie Zhang and Handong Sun
Org. Biomol. Chem., 2012, 10, 5039-5044
DOI: 10.1039/C2OB25192B, Paper

First total synthesis of the biscarbazole alkaloid oxydimurrayafoline
Carsten Börger, Micha P. Krahl, Margit Gruner, Olga Kataeva and Hans-Joachim Knölker
Org. Biomol. Chem., 2012, 10, 5189-5193
DOI: 10.1039/C2OB25842K, Communication

Total synthesis of indole-3-acetonitrile-4-methoxy-2-C-β-D-glucopyranoside. Proposal for structural revision of the natural product
Akop Yepremyan and Thomas G. Minehan
Org. Biomol. Chem., 2012, 10, 5194-5196
DOI: 10.1039/C2OB25821H, Communication

Asymmetric formal synthesis of schulzeines A and C
Jaebong Jang, Jong-Wha Jung, Jaeseung Ahn, Jaehoon Sim, Dong-Jo Chang, Dae-Duk Kim and Young-Ger Suh
Org. Biomol. Chem., 2012, 10, 5202-5204
DOI: 10.1039/C2OB25772F, Communication

First diastereoselective synthesis of methyl caffeoyl- and feruloyl-muco-quinates
Rakesh Jaiswal, Michael H. Dickman and Nikolai Kuhnert
Org. Biomol. Chem., 2012, 10, 5266-5277
DOI: 10.1039/C2OB25124H, Paper

Also of interest is the Natural Products themed issue from MedChemComm, and this OBC blog featuring 10 of the best, most highly cited papers covering natural products from the past 10 years.

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Natural products in OBC

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover natural product chemistry.

We try to keep you updated here, although your best bet is for you to sign up to OBC’s e-alert (free service), and receive the tables of content directly in your inbox every time an issue is published.

The latest natural products’ related articles have been collated here:

Stereoselective synthesis and hormonal activity of novel dafachronic acids and naturally occurring steroids isolated from corals
Ratni Saini, Sebastian Boland, Olga Kataeva, Arndt W. Schmidt, Teymuras V. Kurzchalia and Hans-Joachim Knölker
Org. Biomol. Chem., 2012, 10, 4159-4163
DOI: 10.1039/C2OB25394A, Communication

Elucidation of post-PKS tailoring steps involved in landomycin biosynthesis
Madan K. Kharel, Pallab Pahari, Khaled A. Shaaban, Guojun Wang, Caleb Morris and Jürgen Rohr
Org. Biomol. Chem., 2012, 10, 4256-4265
DOI: 10.1039/C2OB07171A, Paper

Total synthesis of ent-calystegine B4 via nitro-Michael/aldol reaction
Akio Kamimura, Koichiro Miyazaki, Shuzo Suzuki, Shingo Ishikawa and Hidemitsu Uno
Org. Biomol. Chem., 2012, 10, 4362-4366
DOI: 10.1039/C2OB25386K, Paper

Asymmetric synthesis of 2-alkyl-substituted tetrahydroquinolines by an enantioselective aza-Michael reaction
Laura L. Taylor, Frederick W. Goldberg and King Kuok (Mimi) Hii
Org. Biomol. Chem., 2012, 10, 4424-4432
DOI: 10.1039/C2OB25122A, Paper

Stereoselective synthesis of (−)-1-epi-ventiloquinone L and (+)-ventiloquinone L, the monomeric unit of cardinalin 3
Rodney A. Fernandes, Arun B. Ingle and Vijay P. Chavan
Org. Biomol. Chem., 2012, 10, 4462-4466
DOI: 10.1039/C2OB25453K, Paper

Also of Interest:

  • The first articles from MedChemComm’s themed issue on Natural Products are available, including contributions from Professors Craig Townsend and Margaret Brimble

Want to see your natural products article featured on this blog? Submit online here

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The fungal Pestalotiopsis genus on the cover of NPR issue 6

NPR issue 6, 2012, is here!

The cover of this month’s NPR features a review by Du-Qiang Luo et al. which discusses the taxonomy, biology and chemistry of the Pestalotiopsis genus as well as covering biosynthetic relationships and synthesis of metabolites of this genus. Take a look, it will be free to access for 6 weeks!

The taxonomy, biology and chemistry of the fungal Pestalotiopsis genus
Xiao-Long Yang, Jing-Ze Zhang and Du-Qiang Luo
DOI: 10.1039/C2NP00073C

Also in the issue; read the latest Hot Off The Press article by Robert A. Hill and Andrew Sutherland, as well as these reviews:

Pheromones, attractants and other chemical cues of aquatic organisms and amphibians
Scott F. Cummins and John H. Bowie
DOI: 10.1039/C2NP00102K

Electrophilic natural products and their biological targets
Malte Gersch, Johannes Kreuzer and Stephan A. Sieber
DOI: 10.1039/C2NP20012K

The early stages of taxol biosynthesis: An interim report on the synthesis and identification of early pathway metabolites
Jennifer Guerra-Bubb, Rodney Croteau and Robert M. Williams
DOI: 10.1039/C2NP20021J

Glycosynthases as tools for the production of glycan analogs of natural products
Beatrice Cobucci-Ponzano and Marco Moracci
DOI: 10.1039/C2NP20032E

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Natural products in OBC

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover natural product chemistry.

We will try to keep you updated, although the safest bet is for you to sign up to OBC’s e-alert (free service), and receive the tables of content directly in your inbox every time an issue is published.

The latest natural products’ related articles have been collated here:

Synthesis of the anti-influenza agent (−)-oseltamivir free base and (−)-methyl 3-epi-shikimate
Varun Rawat, Soumen Dey and Arumugam Sudalai
Org. Biomol. Chem., 2012, 10, 3988-3990
DOI: 10.1039/C2OB25635E, Communication

Design and synthesis of screening libraries based on the muurolane natural product scaffold
Emma C. Barnes, Vanida Choomuenwai, Katherine T. Andrews, Ronald J. Quinn and Rohan A. Davis
Org. Biomol. Chem., 2012, 10, 4015-4023
DOI: 10.1039/C2OB00029F, Paper

Solar irradiation of the seed germination stimulant karrikinolide produces two novel head-to-head cage dimers
Adrian Scaffidi, Mark T. Waters, Brian W. Skelton, Charles S. Bond, Alexandre N. Sobolev, Rohan Bythell-Douglas, Allan J. McKinley, Kingsley W. Dixon, Emilio L. Ghisalberti, Steven M. Smith and Gavin R. Flematti
Org. Biomol. Chem., 2012, 10, 4069-4073
DOI: 10.1039/C2OB25090J, Paper

Construction of the biaryl-part of vancomycin aglycon via atropo-diastereoselective Suzuki–Miyaura coupling
Timo Leermann, Pierre-Emmanuel Broutin, Frédéric R. Leroux and Françoise Colobert
Org. Biomol. Chem., 2012, 10, 4095-4102
DOI: 10.1039/C2OB25373A, Paper

Stereoselective total synthesis of the acetylenic carotenoids alloxanthin and triophaxanthin
Yumiko Yamano, Mahankhali Venu Chary and Akimori Wada
Org. Biomol. Chem., 2012, 10, 4103-4108
DOI: 10.1039/C2OB25321F, Paper

Synthesis of the unique angular tricyclic chromone structure proposed for aspergillitine, and its relationship with alkaloid TMC-120B
Sebastián O. Simonetti, Enrique L. Larghi, Andrea B. J. Bracca and Teodoro S. Kaufman
Org. Biomol. Chem., 2012, 10, 4124-4134
DOI: 10.1039/C2OB25067E, Paper

Also of Interest:

  • The first articles from MedChemComm’s themed issue on Natural Products are available, including contributions from Professors Craig Townsend and Margaret Brimble

Want to see your natural products article featured on this blog? Submit online here

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