Natural Products in OBC

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although signing up to OBC’s e-alert (free service) means you will receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

Bioinspired total syntheses of terpenoids
Cedric L. Hugelshofer and Thomas Magauer
DOI: 10.1039/C6OB02488B, Perspective

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Total synthesis and confirmation of the revised structures of jiangrines A, C and D
Zhijiang Zhang and Bo Liu
DOI: 10.1039/C6OB02379G, Paper

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Fluorometabolite biosynthesis: isotopically labelled glycerol incorporations into the antibiotic nucleocidin in Streptomyces calvus
Axel Bartholomé, Jeffrey E. Janso, Usa Reilly and David O’Hagan
DOI: 10.1039/C6OB02291J, Communication

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Enantiospecific total syntheses of meroterpenoids (−)-F1839-I and (−)-corallidictyals B and D
Dattatraya H. Dethe, Balu D. Dherange, Saghir Ali and Mahesh M. Parsutkar
DOI: 10.1039/C6OB02322C, Communication

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Second-generation total synthesis of aplyronine A featuring Ni/Cr-mediated coupling reactions
Ichiro Hayakawa, Keita Saito, Sachiko Matsumoto, Shinichi Kobayashi, Ayaka Taniguchi, Kenichi Kobayashi, Yusuke Fujii, Takahiro Kaneko and Hideo Kigoshi
DOI: 10.1039/C6OB02241C, Paper

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The first total synthesis of the marine acetylenic alcohol, lembehyne B – a selective inducer of early apoptosis in leukemia cancer cells
Lilya U. Dzhemileva, Vladimir A. D’yakonov, Aleksey A. Makarov, Evgeny N. Andreev, Milyausha M. Yunusbaeva and Usein M. Dzhemilev  
DOI: 10.1039/C6OB02346K, Paper

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An efficient approach to trans-4-hydroxy-5-substituted 2-pyrrolidinones through a stereoselective tandem Barbier process: divergent syntheses of (3R,4S)-statines, (+)-preussin and (−)-hapalosin
Chang-Mei Si, Lu-Ping Shao, Zhuo-Ya Mao, Wen Zhou and Bang-Guo Wei  
DOI: 10.1039/C6OB02523D, Paper

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A protecting-group-free synthesis of (+)-nephrosteranic, (+)-protolichesterinic, (+)-nephrosterinic, (+)-phaseolinic, (+)-rocellaric acids and (+)-methylenolactocin
Jothi L. Nallasivam and Rodney A. Fernandes
DOI: 10.1039/C6OB02398C, Paper

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Stepwise cyclopropanation on the polycyclopropanated polyketide formation in jawsamycin biosynthesis
Tomoshige Hiratsuka, Hideaki Suzuki, Atsushi Minami and Hideaki Oikawa
DOI: 10.1039/C6OB02675C, Communication

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A novel withanolide with an unprecedented carbon skeleton from Physalis angulata
Cheng-Peng Sun, Andrei G. Kutateladze, Feng Zhao, Li-Xia Chen and Feng Qiu  
DOI: 10.1039/C6OB02656G, Communication

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Total synthesis and biological activity of dolastatin 16
Loida O. Casalme, Arisa Yamauchi, Akinori Sato, Julie G. Petitbois, Yasuyuki Nogata, Erina Yoshimura, Tatsufumi Okino, Taiki Umezawa and Fuyuhiko Matsuda  
DOI: 10.1039/C6OB02657E, Paper

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New compounds from a hydrothermal vent crab-associated fungus Aspergillus versicolor XZ-4
Chengqian Pan, Yutong Shi, Xuegang Chen, Chen-Tung Arthur Chen, Xinyi Tao and Bin Wu  
DOI: 10.1039/C6OB02374F, Paper

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Chemoenzymatic synthesis of unmodified heparin oligosaccharides: cleavage of p-nitrophenyl glucuronide by alkaline and Smith degradation
Xing Zhang, Yongmei Xu, Po-Hung Hsieh, Jian Liu, Lei Lin, Eric P. Schmidt and Robert J. Linhardt  
DOI: 10.1039/C6OB02603F, Paper

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Isoafricanol synthase from Streptomyces malaysiensis
Patrick Rabe, Markiyan Samborskyy, Peter F. Leadlay and Jeroen S. Dickschat  
DOI: 10.1039/C7OB00234C, Communication

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An efficient Ugi-3CR/aza Diels–Alder/Pomeranz–Fritsch protocol towards novel aza-analogues of (±)-nuevamine, (±)-lennoxamine and magallanesine: a diversity oriented synthesis approach
Óscar Vázquez-Vera, Jorge S. Sánchez-Badillo, Alejandro Islas-Jácome, Manuel A. Rentería-Gómez, Shrikant G. Pharande, Carlos J. Cortes-García, Mónica A. Rincón-Guevara, Ilich A. Ibarra, Rocío Gámez-Montaño and Eduardo González-Zamora  
DOI: 10.1039/C6OB02572B, Paper

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Intramolecular macrolactonization, photophysical and biological studies of new class of polycyclic pyrrole derivatives
Suresh Kumar Mondal, Arabinda Mandal, Susanta Kumar Manna, Sk Asraf Ali, Maidul Hossain, Vangala Venugopal, Avijit Jana and Shubhankar Samanta  
DOI: 10.1039/C7OB00160F, Paper

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