Archive for April, 2012

Top ten most accessed articles in March

This month sees the following articles in Natural Product Reports that are in the top ten most accessed:

Hot off the press
Robert A. Hill and Andrew Sutherland
Nat. Prod. Rep., 2012, 29, 435-439
DOI: 10.1039/C2NP90008D

Marine natural products
John W. Blunt, Brent R. Copp, Robert A. Keyzers, Murray H. G. Munro and Michèle R. Prinsep
Nat. Prod. Rep., 2012, 29, 144-222
DOI: 10.1039/C2NP00090C

Cytotoxic and antioxidant marine prenylated quinones and hydroquinones
Suthananda N. Sunassee and Michael T. Davies-Coleman
Nat. Prod. Rep., 2012, 29, 513-535
DOI: 10.1039/C2NP00086E

Triptolide: structural modifications, structure–activity relationships, bioactivities, clinical development and mechanisms
Zhao-Li Zhou, Ya-Xi Yang, Jian Ding, Yuan-Chao Li and Ze-Hong Miao
Nat. Prod. Rep., 2012, 29, 457-475
DOI: 10.1039/C2NP00088A

Phenazines and cancer
A. Cimmino, A. Evidente, V. Mathieu, A. Andolfi, F. Lefranc, A. Kornienko and R. Kiss
Nat. Prod. Rep., 2012, 29, 487-501
DOI: 10.1039/C2NP00079B

Key achievements in the total synthesis of vibsane-type diterpenoids
Jeffrey Y. W. Mak and Craig M. Williams
Nat. Prod. Rep., 2012, 29, 440-448
DOI: 10.1039/C2NP00067A

Natural products as kinase inhibitors
Jing Liu, Yi Hu, David L. Waller, Junfeng Wang and Qingsong Liu
Nat. Prod. Rep., 2012, 29, 392-403
DOI: 10.1039/C2NP00097K

Advances in Aspergillus secondary metabolite research in the post-genomic era
James F. Sanchez, Amber D. Somoza, Nancy P. Keller and Clay C. C. Wang
Nat. Prod. Rep., 2012, 29, 351-371
DOI: 10.1039/C2NP00084A

Pathways for degradation of lignin in bacteria and fungi
Timothy D. H. Bugg, Mark Ahmad, Elizabeth M. Hardiman and Rahman Rahmanpour
Nat. Prod. Rep., 2011, 28, 1883-1896
DOI: 10.1039/C1NP00042J

Peptidoglycan as Nod1 ligand; fragment structures in the environment, chemical synthesis, and their innate immunostimulation
Yukari Fujimoto, Ambara Rachmat Pradipta, Naohiro Inohara and Koichi Fukase
Nat. Prod. Rep., 2012, 29, 568-579
DOI: 10.1039/C2NP00091A

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to Natural Product Reports? Then why not submit to us today or alternatively email us your suggestions.

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Natural Products in OBC

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover natural product chemistry.

We will try to keep you updated, although the safest bet is for you to sign up to OBC’s e-alert (free service) and receive the table of content directly in your inbox every time an issue is published.

 

The latest natural products’ related articles published in issue 18 and issue 19 have been collated here:

The first isocyanide of plant origin expands functional group diversity in cruciferous phytoalexins: synthesis, structure and bioactivity of isocyalexin A
M. Soledade C. Pedras and Estifanos E. Yaya
DOI: 10.1039/C2OB25492A

Synthesis of the macrolactone core of (+)-neopeltolide by transannular cyclization
Gangavaram V. M. Sharma, Sheri Venkat Reddy and Kallaganti V. S. Ramakrishna
DOI: 10.1039/C2OB25151E

A convenient biomimetic synthesis of optically active putative neurotoxic metabolites of MDMA (“ecstasy”) from R-(−)- and S-(+)-N-methyl-α-methyldopamine precursors
Claire-Marie Martinez, Anne Neudörffer and Martine Largeron
DOI: 10.1039/C2OB25245G

Flexible synthesis of montanine-like alkaloids: revisiting the structure of montabuphine
Yifu Guan, Hongbin Zhang, Chengxue Pan, Jia Wang, Rong Huang and Qilin Li
DOI: 10.1039/C2OB25374G, Communication

Stereoselective synthesis of functionalised carbocyclic amides: construction of the syn-(4aS,10bS)-phenanthridone skeleton
Sajjad Ahmad, Michael D. Swift, Louis J. Farrugia, Hans Martin Senn and Andrew Sutherland 
DOI: 10.1039/C2OB25334H, Paper

 

We hope you enjoy the selection! And why not also view MedChemComm‘s themed issue on Natural Products, still growing…

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Cytotoxic and antioxidant marine natural products on the cover of NPR issue 5

Welcome to NPR issue 5, 2012

This month’s striking subaquatic cover features the work of Suthananda N. Sunassee and Michael T. Davies-Coleman at Rhodes University, Grahamstown, South Africa,  with a review on Cytotoxic and antioxidant marine prenylated quinones and hydroquinones.
Focusing on 159 prenylated quinones, hydroquinones and naphthoquinones with reported cytotoxic and/or antioxidant properties isolated from various marine organisms over the past 40 years, the authors highlight trends in the structural distribution of these cytotoxic compounds within the different marine phyla.

Cytotoxic and antioxidant marine prenylated quinones and hydroquinones
Suthananda N. Sunassee and Michael T. Davies-Coleman
Nat. Prod. Rep., 2012, 29, 513-535
DOI: 10.1039/C2NP00086E

Also in this May issue, why not read:

NMR in natural products: understanding conformation, configuration and receptor interactions
Teresa Carlomagno
Nat. Prod. Rep., 2012, 29, 536-554

Cytisine: a natural product lead for the development of drugs acting at nicotinic acetylcholine receptors
Edwin G. Pérez, Carolina Méndez-Gálvez and Bruce K. Cassels
Nat. Prod. Rep., 2012, 29, 555-567

Peptidoglycan as Nod1 ligand; fragment structures in the environment, chemical synthesis, and their innate immunostimulation
Yukari Fujimoto, Ambara Rachmat Pradipta, Naohiro Inohara and Koichi Fukase
Nat. Prod. Rep., 2012, 29, 568-579

Recent discovery of plant-derived anti-diabetic natural products
Hsin-Yi Hung, Keduo Qian, Susan L. Morris-Natschke, Chau-Shin Hsu and Kuo-Hsiung Lee
Nat. Prod. Rep., 2012, 29, 580-606

Access the full issue

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Natural Products in OBC

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover natural product chemistry.

We will try to keep you updated, although the safest bet is for you to sign up to OBC’s e-alert (free service) and receive the table of content directly in your inbox every time an issue is published.

The latest natural products’ related articles from OBC have been collated here:

  • Apocarotenoids in the sexual interaction of Phycomyces blakesleeanus
    Silvia Polaino, Jose A. Gonzalez-Delgado, Pilar Arteaga, M. Mar Herrador, Alejandro F. Barrero and Enrique Cerdá-Olmedo
  • Heteroatom-directed Wacker oxidations. A protection-free synthesis of (−)-heliophenanthrone
    Parag Mukherjee and Tarun K. Sarkar
  • Investigation of the electrophilic reactivity of the cytotoxic marine alkaloid discorhabdin B
    Cary F. C. Lam, Tanja Grkovic, A. Norrie Pearce and Brent R. Copp
  • Organocatalytic enantioselective Michael addition of a kojic acid derivative to nitro olefins
    Jiyu Wang, Qing Zhang, Hui Zhang, Yujun Feng, Weicheng Yuan and Xiaomei Zhang
  • Biotransformation of clovane derivatives. Whole cell fungi mediated domino synthesis of rumphellclovane A
    Giovanni Gontijo de Souza, Thays Silva Oliveira, Jacqueline Aparecida Takahashi, Isidro González Collado, Antonio José Macías-Sánchez and Rosario Hernández-Galán
  • Biomimetic synthesis, antibacterial activity and structure–activity properties of the pyroglutamate core of oxazolomycin
    Plamen Angelov, Yui Kwan Sonia Chau, Paul J. Fryer, Mark G. Moloney, Amber L. Thompson and Paul C. Trippier
  • Ketosulfonyl indoles in the regiodefined synthesis of tryptophols and related indole derivatives
    Alessandro Palmieri and Marino Petrini
  • Also of Interest:

    MedChemComm’s themed issue on Natural Products is growing – have you had a look yet? View all the articles here

    Want to see your natural products article featured on this blog? Submit online here

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