Enzymatic cascade reactions in biosynthesis on the cover of NPR issue 3, 2012

Welcome to NPR issue 3, 2012!

This month’s cover features the work of Kurt Faber et al. at the University of Graz, Austria, with a review on the enzyme-initiated cascade reactions for the ring formation of cyclic terpenoids and polyethers. The authors provide a mechanistic analysis of enzymatic cascade reactions leading to biomimetic strategies for natural product synthesis. 

Also in the issue, read Clay C. C. Wang‘s review article on the  impact of whole genome sequencing on Aspergillus secondary metabolite research:

Pedro N. Leão and coworkers provide insights into the chemical ecology of cyanobacteria, highlighting both evolutionary and chemotaxonomical studies:

Qingsong Liu et al. review the history of several classes of natural products as kinase inhibitors, analyzing their structural binding information and highlighting their therapeutic development potential:

Why not also read on the didemnin family of marine depsipeptides in this review article by Madeleine M. Joullié et al..  The authors highlight the long-standing study of didemnins and its critical application towards the understanding of the molecular mechanism of action of tamandarins and their potential use as therapeutic agents:

 We hope that you enjoy this issue!

View the issue

Digg This
Reddit This
Stumble Now!
Share on Facebook
Bookmark this on Delicious
Share on LinkedIn
Bookmark this on Technorati
Post on Twitter
Google Buzz (aka. Google Reader)