Archive for the ‘Poster Prize’ Category

NJC Poster prize winners at ISMEC 2017

New Journal of Chemistry awarded two poster prizes at the recent ISMEC 2017 (International Symposium on Metal Complexes) conference which took place in Dijon, France. The conference successfully took place from the 11th – 15th June and was attended by 170 registered participants from 19 different countries. The conference consisted of plenary and key note lectures with one plenary lecture from Nobel laureate JP Sauvage. The conference serves as a forum for the study and application of complexes in the fields of Analytical, Biomedical, Environmental, Supramolecular, Inorganic, Physical and Industrial Chemistry.

Participants had the opportunity to contribute either an oral or poster presentation. The following participants were recipients of an NJC poster prize awarded by members of the International committee and the invited speakers: Anna Irto (University of Messina, Italy) and Margaux Galland (ENS Lyon, France) for their respective poster presentations: “Bis-3-hydroxy-4-pyridinones: From the synthesis to the complexation with Al3+ and Fe3+ and the biological assays” and “Competition between luminescence of a lanthanide complex and singlet oxygen generation: Careful choice of the lanthanide atom”.

Further information about the conference can be found on the website.

Anna Irto (right) receiving her NJC poster prize.

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NJC Poster Prize Winners at Metals and Genetics Meeting

Three young scientists were recognized for their contributions at the 6th International Conference on Metals and Genetics, which took place earlier this year at the Indian Institute of Science in Bangalore.

The winners (in no particular order) of the NJC Poster Prizes awarded at this conference were:

Mr Vadde Ramu, National Chemical Laboratory, Pune
Poster title: New imaging reagents for lipid dense regions in live cells and the nucleus in fixed MCF-7 cells

The presented work is part of Vadde’s Ph.D. thesis, carried out under the supervision of Dr. Amitava Das. Vadde will be defending his thesis work this month and is moving to Jena for a post-doctoral position in October.

The presented research work demonstrated the design and synthesis of two new uracil (U) and 5-flurouracil (5-FU) labelled ruthenium(II)-polypyridyl based cellular imaging reagents. These two complexes were found to show affinity towards DNA in the nucleus of the PFA fixed cells. A large Stokes shift (λ = 160 nm) and an appreciably long-lived 3MLCT excited state (λ = 320 ns) in aq. buffer medium (pH 7.4) are other key features of these complexes. Unlike the common nuclear DNA staining reagents like DAPI, these low-cytotoxic reagents are found to be highly stable towards photo-bleaching upon irradiation with λ > 455 nm at the MLCT band for these complexes.

Mr Samsuzzoha Mondal, Tata Institute of Fundamental Research, Mumbai
Poster title: Sensing Signalling Phospholipids with ‘Lanthano-proteins’

Samsuzzoha is a Ph.D. student working in the group of Dr. Ankona Datta. He is in his final year and expects to defend his degree in mid-2017.

His present research is about developing fluorescent probes for imaging the crucial phospholipids involved in cell signaling processes. Currently available genetically encoded fluorescent probes lack ‘on-off’ sensing and have problems with background signal. Hence tracking the spatio-temporal dynamics of phospholipids in a live cellular process with those fluorescent proteins is challenging. The authors are addressing this issue by developing novel fluorescent probes with ‘turn on’ or ‘ratiometric’ fluorescence sensing. The poster presents a ‘lanthano’-protein based ‘turn on’ sensor for phosphatidylserine, a phospholipid involved in cell-death signals mediation and several other signaling processes. Additionally, a recently developed, cell permeable, ratiometric sensor for phosphoinositides, the most important signaling phospholipids in the cellular system, is demonstrated.


Ms Tandrila Das, Indian Institute of Science, Bangalore
Poster title: Vacancy-Engineered Nanoceria: Enzyme Mimetic Hotspots for the degradation of Nerve Agents

Tandrila did the work presented in the poster as a 5th year BS-MS student under the direction of Prof. Govindasamy Mugesh. She is now a 1st year student in the Tri-Institutional Ph.D. program in chemical biology offered by Weill Cornell Medicine, Memorial Sloan-Kettering Cancer Center and The Rockefeller University (all located in New York City).

The study of phosphotriesterase (PTE) enzymes and synthesis of its structural and functional mimics has been a long time interest of the lab. PTE enzymes degrade organophosphorus nerve agents, which are known to inhibit acetylcholine esterase, thus resulting in paralysis, respiratory failure, etc.  For her Master’s thesis, Tandrila worked on developing a nano-mimic of PTE enzyme. The poster work showed that vacancy engineered nanoceria (CeO2) with Ce in both +3 and +4 oxidation states very efficiently act as a catalyst to hydrolyze organophosphorus nerve agents like paraoxon, parathion, etc.

(The photo shows Tandrila on the left with co-author Dr Amit Vernekar, currently a post-doc in the Lippard group at MIT.)

Congratulations to the 3 laureates, and best wishes for continuing success in their research and careers.

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2015 Winners of the New Journal of Chemistry Poster Prize

New Journal of Chemistry is delighted to present the five winners of the NJC poster prizes awarded in 2015.

WGidt - NJC Poster prize 2015Wjatscheslaw Gidt (Ph.D. student working in the group of Prof. Helmut Sitzmann at the Technischen Universität Kaiserslautern, Germany) received the award at the 13th Ferrocene Colloquium (held in Leipzig last winter) for his poster entitled “Synthesis, Structure and Reactivity of the Chromium Complexes [4CpCrX]2 (X = OAc, Cl, I, OTf)”.

His study shows that paramagnetic cyclopentadienylmetal halides of nickel, cobalt and iron, with bulky alkylcyclopentadienyl ligands, are very reactive starting materials for the formation of novel organometallic compounds capable of carbon-carbon bond formation or cleavage.

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This summer, at the International Conference on Advanced Inorganic Complex Nanomaterials held in Namur, Belgium, two young scientists were honoured.SoraChoi - NJC Poster prize 2015

Sora Choi (Ph.D. student under the supervision of Prof. Moonhyun Oh at the Yonsei University, Korea) won a poster prize for her work “Structural and Morphological Transformation of Metal-Organic Frameworks via Destruction and Reconstruction Pathways” in which she reports the structural and morphological transformations of three-dimensional Kagome-like structured hexagonal lumps (In-MIL-68, [In(OH)(BDC)]n) with blunted ends, into three-dimensional quartz structured hexagonal rods (QMOF-2, [InH(BDC)2]n) with pointed ends.

CedricMarien - NJC Poster prize 2015

Cédric Marien (Ph.D. student with Didier Robert at the University of Strasbourg, France and the INRS, Canada) received the award for his research that aims to develop TiO2 based nanostructures for the photo(electro)catalytic removal of organic compounds in water. His poster “Removal of organic pollutants by photocatalysis with TiO2 nanotubes” reported TiO2 nanotubes electrochemically grown on titanium foils. The study shows that the photocatalytic activity of the tubes depends on their morphology, particularly on the internal diameter and wall thickness.

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The XIII International Symposium on Bioinorganic Chemistry held in Karpacz, Poland, in September, also revealed two young talented chemists.

KSokolowski- NJC Poster prize 2015The award-winning poster of Kamil Sokołowski (postdoctoral researcher at the Institute of Physical Chemistry of the Polish Academy of Sciences in the research group of Prof. Janusz Lewiński), entitled “Bio-inspired fixation of CO2 on organozinc hydoxides: efficient routes to novel nanomaterials based on zinc carbonates”, summarized his Ph.D. project. The presented research demonstrated that carbon dioxide in combination with well-defined organozinc hydroxides of the type [RZnOH]n or [(R)xZny(L)z(OH)n], can be successfully utilized for the formation of novel molecular organozinc carbonates, as well as meso- and microporous materials with unique physicochemical properties. The studies underline the great potential of simple organozinc precursors featuring CO2-reactive Zn–OH groups and proton-reactive Zn–C bonds for the design of new functional materials based on zinc carbonate components.

Joanna_Watly - NJC Poster prize 2015Joanna Wątły (Ph.D. student under the supervision of Prof. Henryk Kozlowski at the University of Wroclaw, Poland) was also recognised for her work, “The Impact of the Cu(II) Coordination on the Structural and Thermodynamic Properties of Poly-His Peptides”, in which she studied the coordination of Cu(II) with (His)6-tag peptide (used in IMAC chromatography) and peptide fragments from snake venoms. The results showed that all studied peptides have a high affinity towards Cu(II) ions. Formation of an α-helical structure induced by metal-ion coordination and the occurrence of polymorphic binding states is very characteristic for these peptides, but the most interesting results were obtained for a snake venom peptide fragment with nine histidine residues. The specific role of these nine His residues in venom is unknown, but this peptide may play a key role in the interaction with metal ions and consequently in the inhibition of the snake metalloproteases.

Congratulations to all five winners !

We wish them continuing success in their research and send them our best wishes for 2016!

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Congratulations to the NJC Poster Prize winner at ISXB-1

NJC was pleased to honour Alavi Karim from the University of Gothenburg (Sweden) for her outstanding poster presentation at the 1st International Symposium on Halogen Bonding (ISXB-1) that was held in Porto Cesareo (Italy) on June 18–22.

Alavi Karim is a graduate student in the Department of Chemistry and Molecular Biology where she works under the supervision of Dr. Mate Erdelyi. Her project currently focuses on Understanding Halogen Bonding in Solution.

In her award-winning poster titled “The Nature of [N–Cl–N]+ and [N–F–N]+ Halogen Bonds in Solution” she presented solution-phase NMR spectroscopy data and theoretical studies investigating the geometries and stabilities of the highly reactive, lighter haloniums in comparison to their well-studied iodonium and bromonium centered analogues. Alavi said: “We have characterized three-centre-four-electron halogen bonds, [N–X–N]+, in solution and demonstrated the iodine-, bromine- and chlorine-centred halogen bonds to be static symmetric. In line with fluorine, the [N+–F···N] system shows different behaviour in comparison to the heavier halogens. The complex is asymmetric and thus encompasses one conventional-covalent and one conventional-weak halogen bond. The fluorine- and chlorine-centred systems are highly reactive and could therefore only be stabilized in solution at low temperature. The conclusions drawn from NMR studies were supported by DFT calculations.”

The poster prize committee and winner (from left to right): Giuseppe Resnati, Francesca Baldelli-Bombelli, Alavi Karim and Pierangelo Metrangolo.

Many congratulations to Alavi on receiving her NJC poster prize. She also received a book from the Royal Society of Chemistry and a 1-year electronic subscription to New Journal of Chemistry.

You can read more about the ISXB-1 by visiting their website.

To keep up-to-date with all the latest research, sign up for the journal’s e-alerts.

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Three young chemists honoured at the 8th International Dendrimer Symposium

New Journal of Chemistry sponsored 3 poster prizes at the 8th International Dendrimer Symposium that took place this summer in Madrid, continuing its support of this series of symposia and the dendrimer community in general.

Guang Zhang is a 2nd year Ph.D. student in the group of Klaus Müllen at the MPI for Polymer Research in Mainz, Germany. He is conducting research on polyphenylene dendrimers and their applications for fluorescent blue light emitting diodes. Zhang’s poster reported G1 and G2 dendrimers having triphenylamine on the surface and pyrene in the core, which showed promising properties as blue OLED materials. Guang’s reaction to winning the NJC Poster Prize: “It is a great honor for me to receive the prize. It’s also a big surprise that I can have access to NJC for free for one year.”

Surface Functionalized Polyphenylene Dendrimers for Deep Blue Light  Emitting Diodes
G. Zhang, M. Baumgarten, R. Trattnig, M. Auer, E. J. W. List, K. Müllen

The winner from Spain is Javier Sánchez, who currently is a postdoctoral fellow at the Instituto de Investigación Sanitaria Gregorio Marañón, where he also carried out his Ph.D. research in the group of María Ángeles Muñoz Fernández.  The focus of Javier’s research is anti-HIV activity, but always with an eye to the potential clinical applications. He explains: “I always try to elucidate the mechanisms by which the different dendrimers behave as they do on the HIV-1 cycle.” The research presented at the conference looked at the anti-HIV activity of different carbosilane dendrimers. After development of the dendrimers they were tested using toxicity assays, inflammatory cytokines induction, HIV infection and cell phenotyping by flow cytommetry. This has led to a dendrimer that as a microbicide has anti-HIV activity for different HIV viral strains.

Anti-HIV Activity of Thiol-Ene Carbosilane Dendrimers and Potential Topical Microbicide
J. Sánchez-Rodríguez, L. Díaz, M. Galán, M. Maly, R. Gómez, F. J. de la Mata, J. L. Jiménez, M. A. Muñoz- Fernández

The 3rd winner is from the group of Eric Simanek at Texas Christian University in the USA. Changsuk Lee is now a postdoctoral fellow, after having obtained his Ph.D. under the direction of Daniel Romo at Texas A&M University in 2010. Changsuk works towards the development of drug delivery vehicles by using various sizes and shapes of dendrimers; to date triazine dendrimers are the best delivery vehicles among others tested. The winning poster covered the synthesis of a prodrug platform with paclitaxel, its biodistribution, mice efficacy testing, and molecular dynamic simulations.

Synthesis and Biological Assessment of a Triazine Dendrimer with 16 Paclitaxel Groups
C. Lee, S.-T. Lo, J. Lim, V. C. P. da Costa, S. Ramezani, G. M. Pavan, O. Annuziata, X. Sun, E. E. Simanek

Congratulations to all 3 winners, who received a certificate, RSC book and a one-year NJC subscription.

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NJC poster prize at 5th ECCLS

We are delighted to present the recent poster prizes awarded at the 5th European Conference on “Chemistry for Life Sciences” (5th ECCLS) in Barcelona, that gathers an ensemble of scientists at the crossroads between chemistry, biology, biophysics and material science.

Two young scientists Montserrat Serra-Batiste and Sven Hofmann received NJC Poster Prizes that reward creative and multidisciplinary research works in the chemical sciences.

Montserrat Serra-Batiste is a postdoctoral researcher in the group of the Prof. Ernest Giralt at the Institute for Research in Biomedicine, Barcelona (Spain) working under the supervision of Dr. Natàlia Carulla since September 2010.

Montserrat’s winning poster dealt with well-defined Aß42 oligomers in a biomimetic membrane environment. The idea project started with the idea of Dr Natàlia Carulla of stabilizing Aß oligomers by using an environment similar to what this peptide have in vivo. Different conditions have been testing by different techniques in order to get a stable and homogeneous preparation of Aß oligomers. As a result, an Aß42 hexamer (named (Aß42)6Membrane) has been stabilized which adopts extensive ß-sheet secondary structure and exhibits specific Aß42-Aß42 interactions. Preparation of (Aß42)6Membrane should open the possibility to explore more in deep the role of Aß oligomers in Alzheimer’s disease.

Her future plans include working with Natàlia to characterize the structure and the biological relevance of this Aß42 hexamer and contribute in solving the puzzle of Alzheimer’s disease. Besides research activities Montserrat loves cooking and dancing.

The award-winning poster of Sven Hofmann was entitledCarbaboranes in Short Neuropeptide Y Analogs – Redirecting BiologicalActivity”. Carbaboranes are icosahedral boron-carbon clusters mimicking phenyl rings. In particular, they present a three-dimensional hydrophobic structure and are capable of providing a special type of hydrogen bonding, the so-called proton-hydride bonding. Their unique chemical properties are perfectly suited for improving the biological activity of small bioactive molecules but also of peptide analogs.

Sven is a graduate student working in the research group of Prof. Annette G. Beck-Sickinger at the University of Leipzig, Leipzig (Germany) since October 2010. Working in the field of chemical modification of peptides to gain receptor subtype selectivity and biological stability, he especially focuses on the synthesis of short functionalized peptide ligands as selective diagnostic and therapeutic tools.

His future plans are not fixed yet. However, he will finish his Ph.D. in 2014 and he will apply for a postdoctoral research position abroad. Outside of the lab, Sven’s favorite activities are running, cycling, athletic sport challenges and travelling.

The two laureates received a one-year subscription to the journal and a RSC book. Our thanks go to the organizers of the conference for their help in organizing these awards, and our deep gratitude to all of the senior scientists who served on the jury to select the two following winners:

NJC wishes them continuing success in their research!

A list of all previous NJC Poster Prize winners can be found here.

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NJC Poster Prizes for Synthetic Organic Chemistry

Synthetic organic chemistry is the common theme of the research projects that were awarded NJC poster prizes at 3 regional meetings held this past spring.

Irene accepts her NJC poster prize presented by Prof. Elisabet Dunach.

Ms Justine Giauffret & Dr Irene Notar-Francesco (in the group of Sylvain Antoniotti at the Institute of Chemistry in Nice) shared the first prize for their work on the tandem cyclosimerisation and thioacylation of 1,6-enynes catalysed by supported noble metal nanoparticles. This poster was presented at the PACA region (southeastern France) meeting of the French Chemical Society (SCF) in April.

The unexpected product obtained by Justine and Irene.

 

Nathalie, winner of the NJC poster Prize.

A month later, on the other side of France in Brittany, Ms Nathalie Camus was awarded the NJC poster prize at the northwestern France regional meeting of the SCF. Nathalie is a doctoral student in the group of Raphael Tripier at the Université de Bretagne Occidentale; her poster presented the C-functionalisation of cyclams to make bifunctional chelating ligands for use in nuclear medicine.

Design of the bifunctional chelating cyclam.

 

Prof. Erick Carreira presents Alexandre with his NJC poster prize.

Moving back to the southeast to Grenoble, Mr Alexandre Cannillo was the NJC poster prize winner at the 3rd Francophone Symposium on Total Synthesis. His award-winning work used domino Petasis Diels-Alder reactions to synthesise enantiopure polycyclic compounds. Alexandre is a graduate student at the Institute on the Chemistry of Natural Substances in Gif-sur-Yvette, working under the direction of Jean-Marie Beau and Stéphanie Norsikian.

Polycyclic compounds synthesised from readily available starting materials by domino reactions.

 

Congratulations to all of our winners! We wish them continuing success with their research projects and a bright future in chemistry.

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NJC Poster prize winners at Paris 2013 Symposium on Foldamers

Two NJC poster prizes were awarded during the Paris 2013 Symposium on Foldamers, which was held at the “Les Cordeliers” Conference Centre.

The two laureates received a one-year subscription to the journal and a RSC book. Our thanks go to the organizers of the conference for their help in organizing these awards, and our deep gratitude to all of the senior scientists who served on the jury to select the two following winners:

Elisabeth K. Nyakatura, who received her BSc in chemistry from the Freie Universität Berlin, Germany, in 2007. She then joined the London School of Hygiene and Tropical Medicine and successfully completed a MSc programme in Molecular Biology of Infectious Diseases. After graduating from London in 2008, Elisabeth returned to the Freie Universität to pursue her PhD in the group of Prof. Koksch.Her research is now focused on the application of phage display to identify preferred interaction partners of chemically modified amino acids in helical protein environments. She also implements the unique properties of these nonnatural building blocks in the development of biological active peptides. It is this interface of chemistry and molecular biology that accounts for Elisabeth’s interest in using chemical means to address pathogen-host interactions.

Liam Byrne was born in Wegberg, Germany in 1984. He received his undergraduate and postgraduate education at the University of Leeds; the latter with Prof. Steve Marsden, working on the development of new synthetic applications of the catalytic aza-Wittig reaction. Liam is currently employed as a post-doctoral research associate with Prof. Jonathan Clayden at the University of Manchester. His research has sought to maximise conformational control in a class of helical foldamers and exploit this to achieve stereoselective transformations over long (nanometre) distances.

NJC wishes them continuing success in their research!
A list of all previous NJC Poster Prize winners can be found here.

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NJC Poster prize winners at E-WISPOC 2013

Two NJC poster prizes were awarded during the European-Winter School on Physical Organic Chemistry, which was held in Bressanone (Italy) from 27 January to 1 February 2013.

The two laureates received a one-year subscription to the journal and a RSC book. Our thanks go to the organizers of the conference for their help in organizing these awards, and our deep gratitude to all of the senior scientists who served on the jury to select the two following winners:

Giulia Iadevaia, who graduated in chemistry from the University La Sapienza in Rome and completed her Masters thesis under the supervision of Prof. Antonella Dalla Cort. During this time, she collaborated with Prof. Giulia Licini (University of Padova) and Prof. Kari Rissanen (University of Jyväskylä), where she carried out part of the work. Giulia is currently undertaking a PhD under the supervision of Prof. Christopher Hunter (University of Sheffield), studying cooperative hydrogen bonded systems. Her current research interest is in supramolecular chemistry, molecular recognition, and host-guest complexes.

Matea Vlatković was educated at the University of Zagreb. For her master research project, she moved to the University of Warsaw to work on constitutionally dynamic anion receptors with Dr. Michał Chmielewski. Matea is currently a PhD student under the supervision of Prof. Ben Feringa at the University of Groningen.  Her main research interests include organic synthesis, molecular switches, supramolecular chemistry, and catalysis. Besides her research activity, Matea enjoys dancing salsa, reading, traveling, and hiking.

NJC wishes them continuing success in their research!
A list of all previous NJC Poster Prize winners can be found here.
From left to right: Christiano Zonta, Laurent Vial, Giulia Iadevaia, Matea Vlatković, and Giulia Licini.
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The last of 2012’s NJC Poster Prize winners

Yang Wang

 Yang Wang, a young Chinese Ph.D. student in the group of Dr Ling Peng at the CINaM in Marseille, won the NJC Poster Prize awarded at the 7th Organic Chemistry Meeting of Marseille. His research interests lie in synthesizing different kinds of dendrimers and their bio-application in drug delivery, especially nucleic acids drug delivery.  

Yang’s winning poster was entitled  “Synthesis of amphiphilic poly(aminoester) dendrimers  for drug delivery”. Poly(aminoester) dendrimers show great promise as biodegradable nanocarriers for drug delivery due to their advantageous properties: biodegradability, potentially lower toxicity and possibility of diverse chemical conjugations. This work presented the design and synthesis of amphiphilic poly(aminoester) dendrimers bearing amine terminal functionalities for effective drug delivery.  

Konstantin Chegaev

 Two NJC poster prizes were awarded at the 6th French-Italian Chemistry Days, also held in Marseille and organized under the auspices of the French Chemical Society (SCF).  

Dr Konstantin Chegaev is a researcher in the group of Prof. Roberta Fruttero, in the Department of Pharmaceutical Science and Technology of the University of Torino. He is focusing his research in the field of anticancer drugs with particular interest to the problem of multi-drug resistance.  

The title of Konstantin’s poster was “Multitarget drugs: NO-donor doxorubicins”. The major result presented in this work is the reversal of multitarget drug resistance in doxorubicin-resistant cell lines. The use of exogenous NO-donor molecules provoke the nitration of tyrosine residue of MDR pumps with consequent increase of doxorubicin accumulation and toxicity in HT29dx cell lines. The authors believe that NO-donor doxorubicins warrant further investigations in preclinical and clinical settings.  

Momar Toure

  

Ph.D. student Momar Toure was the 2nd laureate at this meeting. He is completing his studies in the groups of Jean-Luc Parrain and Olivier Chuzel in the iSm2 laboratory at the University of Aix-Marseille.  

Momar’s poster was on “Self-assembled calixborate macrocyclic anion receptors“. Well-designed macrocyclic calixborates  incorporating imidazolium functinalities were synthesized in high yield. These new macrocycles display a high binding affinity for halides and oxoanions.  

Congratulations to all 3 laureates!
  

A list of all previous NJC Poster Prize winners can be found here.

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