Author Archive

Congratulations to our Highly Cited board members!

We are delighted to have many world-leading researchers on our Editorial and Advisory Boards, helping to guide Nanoscale Horizons and Nanoscale as high impact journals publishing first reports of exceptional significance and high quality research respectively across nanoscience and nanotechnology.

Many of our Board members have been recognized in Clarivate Analytics’ recently published 2017 Highly Cited Researchers list!

Congratulations from the Nanoscale Horizons and Nanoscale teams to…

…Editorial Board members

…and Advisory Board members

  • Chad Mirkin, Northwestern University, USA
  • Rodney Ruoff, Ulsan National Institute of Science and Technology, South Korea
  • Hua Zhang, Nanyang Technological University, Singapore
  • Zhenan Bao, Stanford University, USA
  • Yunqi Liu, Chinese Academy of Sciences, China

Click on their names to check out some of their published work in Nanoscale.

If you think you might have some work that represents a brand new concept of exceptional significance then get in touch on nanoscalehorizons-rsc@rsc.org.

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Fully degradable protein nanocarriers by orthogonal photoclick tetrazole–ene chemistry

With rapid advances in nanomedicine, non-toxic, biodegradable targeted nanocarriers that can encapsulate active drugs or biological molecules and can confer controllable release of its payloads at the target sites have emerged as novel theranostic tools for more sensitive and accurate diagnostics and more effective therapies. As such, by our evolving understanding of diseases and the impact of the current nanocarriers, moving towards the development of further enhanced and smart, stimuli responsive polymers is trivial. However, it is not without challenge to design such materials in a reproductive and controlled manner. Therefore, new synthesis methods and protocols that can lead to multi-component nanocarriers of optimal size and shape that are receptive to disease pathology and biochemistry and are fully non-toxic, biodegradable and allow a targeted distribution are highly timely.

 

Keti Piradashvili et al. recently reported in Nanoscale Horizons an effective and yet simple preparation of such nanocarriers that are stable in blood plasma and are enzymatically degradable. For their preparation, a light-triggered and catalyst-free tetrazole–ene cycloaddition (TET-click) on the bio-degradable natural polymers, human serum albumin (HSA) was achieved.  First, TET was attached to HSA by Steglich amidation; and second; an inter-facial cross-linking reaction of the TET-HSA in a water-in-oil mini-emulsion was used to obtain the stable fluorescent aqueous nanocarriers by irradiation of the mixture with UV light at 254 nm. (Fig.1).

 

Figure 1. Preparation of protein nanocarriers. (a) Non-fluorescent protein–TET conjugates were cross-linked by dinorbornene in inverse mini-emulsion to obtain self-fluorescent protein nanocarriers; (b) reaction mechanism of the bioorthogonal UV-light induced 1,3 dipolar tetrazole–ene cycloaddition; (c) experimental setup with a peristaltic pump pumping the emulsion through a quartz cuvette with the UV-lamp placed in front; (d) average size of various protein nanocarriers; (e) TEM image of the protein nanocarriers. Image reproduced with permission of the Royal Society of Chemistry.

 

The synthesized nanocarriers were shown to encapsulate a high drug payload (R848) of more than 90%. Besides, the encapsulated R848 nanocarriers were highly internalized into the derived dendritic cells (BMDCs) and released in a functional manner, as well as being extremely stable. There were no signs of aggregation or degradation, even after ca. 8 months of storage, so no leakage of the R848 occurred.

 

This approach could be utilized as a platform to design a variety of encapsulation on a vast range of proteins. Further preclinical and clinical testing is needed for the clinical translation of such nanotherapeutics. Nevertheless, the efficient methods reported here could play a pivotal roll along the evolutionary and revolutionary path of nanotherapeutics.

 

Read the full article here:
Keti Piradashvili, Johanna Simon, David Paßlick, Julian R. Höhner, Volker Mailänder, Frederik R. Wurm and Katharina Landfester
Nanoscale Horiz., 2017, Advance Article. DOI: 10.1039/C7NH00062F

 

Dr. Orza is a member of the Community Board for Nanoscale Horizons. She is a Senior Research Scientist in the Laboratory of Nanomedicine at Emory Medical School, USA. She completed her Ph.D. on the development of therapeutic nanoparticles in the Department of Chemistry, Liverpool University, UK and Babes Bolyai University, Romania. Her research is focused on developing hybrid-engineered nanomaterials for biomedical applications, such as: tissue engineering and cancer treatment/diagnosis. Creative approaches to the design of such nanomaterials come from chemistry, biotechnology, biology/medicine, and engineering. Additionally, Dr. Orza is a Director and Chief Scientist at IndagoMed. LLC, USA, a company focused on creating performance products through the use of nanotechnology.

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Conference Promotion – GRAPCHINA 2017

Materials Horizons and Nanoscale Horizons are proud to be partnering with GRAPCHINA 2017, which takes place on 24 – 26 September 2017 at Nanjing International Exhibition Centre, China.

This International Graphene Global Innovation Conference has become a significant commercial and academic event that gathers approximately 2000 representatives for all stakeholders involved in graphene technologies, bringing top level speakers and delegates from the industries, NGOs and academia together with senior policy makers from the EU’s flagship program and national government.

Key speakers include:

  • Sir Andre Geim, Nobel Prize winner
  • Professor Yong Gan, Vice President of the Chinese Academy of Engineering
  • Professor Andrea C. Ferrari, Founding Director of the Cambridge Graphene Centre (and Associate Editor for Nanoscale)
  • and many more!

The conference will be divided into three parallel symposia, focusing on different topics like graphene and 2D materials frontier research, graphene-related emerging industries, graphene application in traditional industries. The symposia cover areas of fundamental research, graphene manufacturing, energy application, health and environment, sensors and communication, composites application, etc. There will also be three special forums, aiming to push international collaboration, accelerate characterization and standardization method, and promote national graphene industry bases. The topics center on promising commercial projects, graphene characterization method, graphene standardization, and local supports for graphene industry bases.

Important Dates:

  • Early Registration 12 July 2017
  • Poster Submission 15 August 2017
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Conference promotion – NFA 2017

Nanoscale Horizons is proud to support a poster prize at the 3rd International Conference on Nanomaterials: Fundamentals and Applications (NFA 2017). This meeting is organised by Pavol Jozef Šafárik University and Slovak Chemical Society, Bratislava and will take place in Štrbské Pleso, Slovakia, from October 09. – 11. 2017.

The following topics will be covered by a program of international speakers:
1. Nanomaterials, nanocomposites and nanostructured surfaces
2. Bioinspired and medical nanomaterials
3. Nanomaterials for energy applications
4. Advanced preparation methods and characterization techniques of nanomaterials
5. New applications and new properties of nanomaterials
6. Nanofertilizers
7. Nanomaterials and components for electronic devices

Registration ends 1 October.

Submit abstracts by 18 September to be in with a chance of winning the Nanoscale Horizons poster prize.

 

For more information visit http://nfa2017.science.upjs.sk/

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ANNIC 2017

ANNIC 2017 the Applied Nanotechnology and Nanoscience International Conference will take place on 18 – 20 October at Rome Eventi – Piazza di Spagna in Rome. This annual event hosts high-profile plenary speakers, world-class researchers, oral and poster presentations, workshops, sponsor exhibits, and afterworks, so it is a great opportunity to share your research findings with a wide audience, promote knowledge exchange, and network.

A wide range of topics are covered in the plenary lectures, invited talks and workshops, including nanoelectronics, nanophotonics, nanomaterials, nanomanufacturing, nanomedicine & nanobiotechnology, and nanotechnology for energy applications. A list of confirmed plenary speakers can be found here.

Submission is open for abstracts for oral presentations, posters, video presentations or workshop presentations. To be in with a chance of winning one of three prizes sponsored by Nanoscale Horizons and Molecular Systems Design & Engineering submit your abstracts now.

Visit the event web page for registration and submission details.

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Prize Winners at PANIC nano Conference 2017

Congratulations to the Nanoscale Horizons Award winners from the PhoBiA Annual Nanophotonics International Conference (PANIC 2017)! This interdisciplinary conference aimed to gather young scientists working on the borders between chemistry, physics, and biology in order to help them to share their knowledge on photonoics, nanotechnology, biotechnology, materials science, and organic electronics.

 

The best oral presentation was awarded to Maciej Chrzanowski, for his talk on Synthesis of double shell type-II semiconductor nanocrystals for lasing applications.

The best poster presentation was awarded to Katarzyna Brach, for her poster describing DNA liquid crystals doped with AuAg nanoclusters.

 

 

 

Both winners will receive a free personal online subscription to Nanoscale for one year, as well as a signed certificate from the Executive Editor of Nanoscale Horizons.

Congratulations from the Nanoscale Horizons Team!

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2017 International Conference on Nanotechnology for Renewable Materials

We are proud to be supporting TAPPI’s International Conference on Nanotechnology for Renewable Materials, which will be held in Montreal, Canada on 5 – 8 June.

This meeting provides a forum for both academic and industry participants to discuss the latest advances in renewable nanomaterials, with particular focus on cellulose-based nanomaterials.

 

 

Some of the topics covered will be:
• Biomedical Applications
• Composites
• Electronics
• Paper and Packaging
• Characterization
• Functional Materials
• Surface Mediated Assembly

Register before 10 May for early-bird rates.

 

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PhoBiA Annual Nanophotonics International Conference 2017

The Photonics and Bionanotechnology Association “PhoBiA” are inviting all young scientists and students to attend the 8th Edition of the PhoBiA Annual Nanophotonics International Conference “PANIC” which will take place from 24 – 26 April, 2017 in Wroclaw, Poland.

This meeting intends to gather students and young scientists working on the borders between chemistry, physics, and biology to enable them to share knowledge by presenting their work in a conference setting. A plenary lecture will take place each day, presented by a renowned scientist from the field of photonics, bio-, or nanotechnology.

Nanoscale Horizons is proud to sponsor student prizes for the best poster and the best oral presentation! The abstract submission deadline is only days away, so to be in with a chance of winning a signed certificate and one years free subscription to the journal Nanoscale, published by the Royal Society of Chemistry submit by 26 March!

PANIC 2017 is organised by students for students, so sign up before 2 April to take part.

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ICONAN 2017

ICONAN 2017 International Conference on Nanomedicine and Nanobiotechnology took place from 25 – 27 September at University Pompeu Fabra in Barcelona, welcoming world-class researchers from around the world to promote the exchange of knowledge.

 

We would like to extend our congratulations to the three prize winners who all won prizes sponsored by Nanoscale Horizons and Molecular Systems Design & Engineering!

 

Congratulations to Dr Havva Acar for winning the outstanding abstract prize.

 

 

 

 

 

 

 

 

Congratulations to Geeta Arya for winning the best poster prize.

 

 

 

 

 

 

 

 

 

Congratulations to Julio Manuel Rios de la Rosa for winning the best student abstract prize.

 

 

 

 

 

 

 

Visit the conference web page for a more details.

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