Top 10 Reviewers for Metallomics

In celebration of Peer Review Week, with the theme of Recognition for Review – we would like to highlight the top 10 reviewers for Metallomics in 2016, as selected by the editorial team for their significant contribution to the journal.

We would like to say a massive thank you to these reviewers as well as the Metallomics board and all of the metals in biology community for their continued support of the journal, as authors, reviewers and readers.

Name

Institution

Yasumitsu Ogra

Chiba University

Sharon La Fontaine

Deakin University

Dennie Thiele

Duke University

Rachel Austin

Columbia University

Martina Ralle

Oregon Health and Science University

Chunying Chen

National Center for Nanosciences and Technology of China

Dominic Hare

University of Technology Sydney

Nigel Robinson

Durham University

Katherine Franz

Duke University

Suning Wang

Northwestern University

As a little added bonus to celebrate Peer Review Week, for the next four weeks our reviewers will be in with a chance of winning a fantastic prize! Simply submit a review for any of our journals between 19 September and 16 October 2016 and you will be automatically eligible for a chance to win one of our fantastic prizes.

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Themed issue on Mammalian Copper Transport and Related Disorders now published

The new themed issue for Metallomics titled “Mammalian Copper Transport and Related Disorders” is now published.

This themed issue, Guest Edited by Professors David Giedroc, Sharon La Fontaine and Richard Burke, marks the retirement of three pioneers in mammalian copper biology, Professors Jim Camakaris, Julian Mercer and Joseph Prohaska.

This issue showcases research on the role of copper in health and disease, the chemistry and structural biology of key copper homeostasis proteins, the development of cutting edge imaging tools and therapies, and the model systems that have helped elucidate the function and regulation of this intriguing and exciting metal in the context of mammalian copper homeostasis.

You can read the issue editorial by the Guest Editors here as well as special editorials by Joseph Prohaska, Julian Mercer and James Camakaris.

Managing Editor, Guy Jones, and Editorial Board chair and Guest Editor of the themed issue, David Giedroc, attended the 10th International Copper Meeting on September 25 – 30, 2016 in Sorrento, Italy and were very pleased to be able to meet with many contributors to the issue as well as Jim, Julian and Joe.

Left to Right: Joe Prohaska, Jim Camakaris, Julian Mercer and David Giedroc, at the Copper meeting

Joe, Jim and Julian at the Copper meeting in Sorrento

We hope you enjoy this issue of Metallomics!

Why not submit your high impact research to Metallomics today. Information about the scope of the Journal can be found here.

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New Editorial Board Chair for Metallomics: David Giedroc

After four fantastic years, Wolfgang Maret, Chair of Metallomics, is coming to the end of his term. Wolfgang took over the role in 2012, over which period he has helped the Royal Society of Chemistry with numerous activities, such as guest editing the 2014 Zinc in the Biosciences themed issue, chairing four Editorial Board meetings (including two Editors’ Symposia in Brussels and London) and supporting the journal at numerous conferences and events, particularly within the zinc community.  We wish him all the best for the future and value his continued contribution to the journal as an Advisory Board member.

David Giedroc, new Chair of the Metallomics Editorial Board

We are pleased to announce that the new Chair of the Editorial Board for Metallomics is David Giedroc, Indiana University, USA. Professor Giedroc’s research interests fall under a common umbrella coined the biophysical chemistry of infectious disease.  He has long-standing interests in transition metal homeostasis and more recent interests in hydrogen sulfidesensing and reactive sulfur species in major nosocomial bacterial pathogens and seeks a molecular-level understanding of macromolecular structure, dynamics and regulation, and uses the tools of biophysical chemistry, bioinorganic chemistry, proteomic profiling and NMR structure determination.

As an already experienced member of the journal’s Editorial Board, David is more than qualified to take the reins from Wolfgang, and we are looking forward to his term as Chair of Metallomics.

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World Alzheimer’s Month 2016

World Alzheimer’s Month September 2016 marks the fifth global World Alzheimer’s Month- an international campaign to raise awareness and challenge stigma.

In support of this event, we have compiled a new online collection bringing together Alzheimer’s and Dementia research published in Metallomics, Analyst, Analytical Methods, Food & Function and Toxiology Research since the beginning of 2015.

Check out the collection here, which will be free to access for one week from Monday September 19 to include the official World Alzheimer’s Day, September 21 2016.

The theme for World Alzheimer’s Month 2016 is Remember Me. You can get involved by sharing your favourite memories, or memories of a loved one, on social media this September with the hashtags #RememberMe #WAM2016.

You can find out more about World Alzheimer’s Month 2016 here.

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Check out the newly updated Metals in Marine Biochemistry online collection

The Metals in Marine Biochemistry online collection has now been expanded to include additional reports in this field and to highlight emerging high-impact areas of research on metals in marine biochemistry.

The collection will become a resource for researchers in the field and new articles will be added to this collection as they are published in Metallomics.

Read the collection here.

Do you work in this area? Then why not submit to Metallomics today!

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Themed issue highlighting the work presented at the 5th International Conference on Metallomics now published

The new themed issue for Metallomics highlighting work from the 5th International Conference on Metallomics, September 9 – 12, 2015, Beijing, China and Guest Edited by  Professors Chunying Chen, Xingrong Zhang and Zhifang Chai is now published.

We hope you enjoy the issue!

Why not submit your high impact research to Metallomics today. Information about the scope of the Journal can be found here.

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Top 10 most accessed Metallomics articles from April – June 2016

From April – June 2016, our most downloaded Metallomics articles were:

Serum ferritin is an important inflammatory disease marker, as it is mainly a leakage product from damaged cells
Douglas B. Kell and Etheresia Pretorius
Metallomics, 2014,6, 748-773
DOI: 10.1039/C3MT00347G, Perspective

Behavior of platinum(IV) complexes in models of tumor hypoxia: cytotoxicity, compound distribution and accumulation
Ekaterina Schreiber-Brynzak, Verena Pichler, Petra Heffeter, Buck Hanson, Sarah Theiner, Irene Lichtscheidl-Schultz, Christoph Kornauth, Luca Bamonti, Vineet Dhery, Diana Groza, David Berry, Walter Berger, Markus Galanski, Michael A. Jakupec and Bernhard K. Keppler
Metallomics, 2016,8, 422-433
DOI: 10.1039/C5MT00312A, Paper

Therapeutic and analytical applications of arsenic binding to proteins
Beibei Chen, Qingqing Liu, Aleksandra Popowich, Shengwen Shen, Xiaowen Yan, Qi Zhang, Xing-Fang Li, Michael Weinfeld, William R. Cullen and X. Chris Le
Metallomics, 2015,7, 39-55
DOI: 10.1039/C4MT00222A, Critical Review

Nickel-responsive regulation of two novel Helicobacter pylori NikR-targeted genes
M. D. Jones, I. Ademi, X. Yin, Y. Gong and D. B. Zamble
Metallomics, 2015,7, 662-673
DOI: 10.1039/C4MT00210E, Paper

The role of vanadium in biology
Dieter Rehder
Metallomics, 2015,7, 730-742
DOI: 10.1039/C4MT00304G, Critical Review

Selenium, selenoproteins and neurodegenerative diseases
Bárbara Rita Cardoso, Blaine R. Roberts, Ashley I. Bush and Dominic J. Hare
Metallomics, 2015,7, 1213-1228
DOI: 10.1039/C5MT00075K, Critical Review

The use of X-ray absorption and synchrotron based micro-X-ray fluorescence spectroscopy to investigate anti-cancer metal compounds in vivo and in vitro
Alfred A. Hummer and Annette Rompel
Metallomics, 2013,5, 597-614
DOI: 10.1039/C3MT20261E, Tutorial Review

Insights on the interaction of alpha-synuclein and metals in the pathophysiology of Parkinson’s disease
Eleonora Carboni and Paul Lingor
Metallomics, 2015,7, 395-404
DOI: 10.1039/C4MT00339J, Minireview

A platinum complex that binds non-covalently to DNA and induces cell death via a different mechanism than cisplatin
Kogularamanan Suntharalingam, Oscar Mendoza, Alexandra A. Duarte, David J. Mann and Ramon Vilar
Metallomics, 2013,5, 514-523
DOI: 10.1039/C3MT20252F, Paper

Defining the metal binding pathways of human metallothionein 1a: balancing zinc availability and cadmium seclusion
Gordon W. Irvine, Tyler B. J. Pinter and Martin J. Stillman
Metallomics, 2016,8, 71-81
DOI: 10.1039/C5MT00225G, Paper

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Open Access papers in Metallomics

We are very pleased to share with you below some of the latest Open Access papers published in Metallomics that may be of interest to you. These research papers are free to access for all – we hope you enjoy reading them.

The biological chemistry of the transition metal “transportome” of Cupriavidus metallidurans
Dietrich H. Nies
Metallomics, 2016,8, 481-507
DOI: 10.1039/C5MT00320B, Tutorial Review

Mass spectrometry of B. subtilis CopZ: Cu(I)-binding and interactions with bacillithiol
Kristine L. Kay, Chris J. Hamilton and Nick E. Le Brun
Metallomics, 2016, Advance Article
DOI: 10.1039/C6MT00036C, Paper

Chemistry of bone remodelling preserved in extant and fossil Sirenia
Jennifer Anné, Roy A. Wogelius, Nicholas P. Edwards, Arjen van Veelen, Konstantin Ignatyev and Phillip L. Manning
Metallomics, 2016,8, 508-513
DOI: 10.1039/C5MT00311C, Paper

Behavior of platinum(IV) complexes in models of tumor hypoxia: cytotoxicity, compound distribution and accumulation
Ekaterina Schreiber-Brynzak, Verena Pichler, Petra Heffeter, Buck Hanson, Sarah Theiner, Irene Lichtscheidl-Schultz, Christoph Kornauth, Luca Bamonti, Vineet Dhery, Diana Groza, David Berry, Walter Berger, Markus Galanski, Michael A. Jakupec and Bernhard K. Keppler
Metallomics, 2016,8, 422-433
DOI: 10.1039/C5MT00312A, Paper

Lead and manganese levels in serum and erythrocytes in Alzheimer’s disease and mild cognitive impairment: results from the Australian Imaging, Biomarkers and Lifestyle Flagship Study of Ageing
Dominic J. Hare, Noel G. Faux, Blaine R. Roberts, Irene Volitakis, Ralph N. Martins and Ashley I. Bush
Metallomics, 2016,8, 628-632
DOI: 10.1039/C6MT00019C, Paper

Endogenous Cu in the central nervous system fails to satiate the elevated requirement for Cu in a mutant SOD1 mouse model of ALS
J. B. Hilton, A. R. White and P. J. Crouch
Metallomics, 2016, Advance Article
DOI: 10.1039/C6MT00099A, Paper

Surface binding, localization and storage of iron in the giant kelp Macrocystis pyrifera
Eric P. Miller, Hendrik Auerbach, Volker Schünemann, Teresa Tymon and Carl J. Carrano
Metallomics, 2016,8, 403-411
DOI: 10.1039/C6MT00027D, Paper

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Expanded Nickel in Biology online collection now available

The Nickel in Biology online collection has now been expanded to include additional reports in this field which highlight emerging high-impact research on the roles and distribution of nickel in biology.

Curated by Editorial Board member Professor Deborah Zamble, the hope is that the collection will become a resource for researchers in the field and new articles will be added to this collection as they are published in Metallomics.

A link to the collection can be found here.

Do you work in this area? Then why not submit to Metallomics today!

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Editor’s Choice: Chris Orvig selects his top papers from recent issues of Metallomics

Metallomics Editorial Board Member, Professor Chris Orvig (University of British Columbia) selects his Top 5 articles from recent issues of Metallomics.

Professor Orvig is Director of the Medicinal Inorganic Chemistry Group and Professor of Chemistry and Pharmaceutical Sciences at the University of British Columbia. His research interests are medicinal inorganic chemistry and coordination chemistry and he has been involved over the years with radiopharmaceutical chemistry, metal ion decorporation, and metal ion neurotoxicology, as well as chemotherapeutic metal complexes and ligands.

Read Professor Orvig’s Editor’s Choice selection via the links below – all articles are free to access for the next 4 weeks!


The role of vanadium in biology

Dieter Rehder, Metallomics, 2015, 7, 730, DOI: 10.1039/c4mt00304g

A timely and comprehensive review, from one of the world’s experts, on relevant bioinorganic chemistry of vanadium, an element of many roles and even more questions.  The review highlights the many roles of vanadium in nature and biology, including its transport, speciation, redox, acquisition and natural sources, as well as medicinal applications.  A detailed readable and timely account.

Boron uptake, localization, and speciation in marine brown algae

Eric P. Miller et al., Metallomics, 2016, 8, 161, DOI: 10.1039/c5mt00238a

Boron’s marine concentrations exceed those in its terrestrial environments significantly and yet it is a required element throughout the plant kingdom.  This paper examines boron in two species of brown algae looking at uptake, localization, and speciation with a variety of physical techniques (including 11B NMR) concluding that it is bound to cell walls (possibly as alginate) and as mannitol esters.

A time-course analysis of changes in cerebral metal levels following a controlled cortical impact

Stuart D. Portbury et al., Metallomics, 2016, 8, 193, DOI: 10.1039/c5mt00234f

An unusual study of the “metallo-pathological” features of traumatic brain injury including increased brain concentrations of non-heme Fe and free Zn.  The study examines regional and time point specific elevations in Fe, Zn and Cu that were detected immediately and up to 28 days after a controlled cortical impact; such an impact results in both significant and sustained alterations in normal metal levels in the brain. A brutal but fascinating study.

LA-ICP-MS imaging in multicellular tumor spheroids – a novel tool in the preclinical development of metal-based anticancer drugs

Sarah Theiner et al., Metallomics, 2016, 8, 398, DOI: 10.1039/c5mt00276a

An interesting proof-of-principle combination of a hyphenated mass spectrometry technique for elemental imaging with tumour spheroids, a useful macroscopic three dimensional cancer cell model, to examine Pt drug accumulation from three anti-tumour agents.  Excellent spatial resolution allowed imaging of Pt on the periphery and in the necrotic core of the spheroids, as well as estimations of drug penetration of the tumours.

Chemistry of bone remodelling preserved in extant and fossil Sirenia

Jennifer Anné et al., Metallomics, 2016, 8, 508, DOI: 10.1039/c5mt00311c

A combination of high energy X-ray techniques is used to characterise, localize and quantify trace elements (particularly Ca and Zn) within bone tissues of aquatic mammals (e.g. manatees). Their dense bone structure showed concentrations of the elements to be comparable whether extant or fossil material was studied suggesting distributions, concentrations, and chemical coordination of the elements indicate the chemistry of bone remodelling has been preserved for 19 million years.  A most unusual and potentially broad-reaching study.

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