Author Archive

Recent HOT articles in Metallomics

Take a look at our selected HOT articles just published in Metallomics: these papers will be free to read for the next four weeks. Enjoy!

An integrative computational model for large-scale identification of metalloproteins in microbial genomes: a focus on iron–sulfur cluster proteins
Johan Estellon, Sandrine Ollagnier de Choudens, Myriam Smadja, Marc Fontecave and Yves Vandenbrouck  
Metallomics, 2014, Advance Article
DOI: 10.1039/C4MT00156G, Paper

Metal binding properties of the zinc finger metallome – insights into variations in stability
Anna Miłoch and Artur Krężel  
Metallomics, 2014, Advance Article
DOI: 10.1039/C4MT00149D, Paper

Intracellular reduction/activation of a disulfide switch in thiosemicarbazone iron chelators
Eman A. Akam, Tsuhen M. Chang, Andrei V. Astashkin and Elisa Tomat  
Metallomics, 2014, Advance Article
DOI: 10.1039/C4MT00153B, Paper

Copper-dependent and -independent hypoxia-inducible factor-1 regulation of gene expression
Zhen Zhang, Liying Qiu, Chen Lin, Hong Yang, Haiying Fu, Rui Li and Y. James Kang  
Metallomics, 2014, Advance Article
DOI: 10.1039/C4MT00052H, Paper

Evaluation of Fe uptake and translocation in transgenic and non-transgenic soybean plants using enriched stable 57Fe as a tracer
Silvana R. Oliveira, Amauri A. Menegário and Marco A. Z. Arruda  
Metallomics, 2014, Advance Article
DOI: 10.1039/C4MT00162A, Paper

The cation diffusion facilitator protein EmfA of Rhizobium etli belongs to a novel subfamily of Mn2+/Fe2+ transporters conserved in α-proteobacteria
Ciro Cubillas, Pablo Vinuesa, Maria Luisa Tabche, Araceli Dávalos, Alejandra Vázquez, Ismael Hernández-Lucas, David Romero and Alejandro García-de los Santos  
Metallomics, 2014, Advance Article
DOI: 10.1039/C4MT00135D, Paper

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BioMetals 2014, Duke University – Abstract Submission site is now open!

 The BioMetals 2014 Abstract Submission site is now open!  BioMetals 2014 is a conference exploring metals in biology, medicine, and the environment that will be held at Duke University, July 13-18, 2014. There is an excellent slate of invited speakers -  please visit the homepage for information about abstract submission, registration, and accommodations. 

Submit your abstract!

Follow the guidelines on our website to prepare a 250-word abstract as a pdf file.  Be sure to indicate during the Abstract Submission process if you would like to be considered for the opportunity to give a short talk. The Abstract Submission Deadline is May 15th, 2014.  

Register now for discounted prices: 

The price of registration includes:
Participation in all lectures and poster sessions
Admission to the Welcome Reception on Sunday, July 13
Lunch each day (July 14-17)
Access to break room (with snacks and drinks) throughout each day (July 14-17)
Conference materials  

Important Dates:  July 13-18, 2014

Sunday, July 13 – Registration, Welcome Reception, and Evening Plenary Lecture
Thursday, July 17 – Full Program and Evening Banquet
Friday, July 18 – Departure

Please join us for this exciting opportunity for in-depth learning, high-impact collaboration, and historically fruitful networking. Please visit the website for more information and contact us with any questions you have . 

Symposium Organizers
Al Crumbliss, Kathy Franz, and Dennis Thiele, Duke University, Durham, NC, USA

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Call for Proposals: IPA, Health Research Group – Science Task Force (HSRG)

The International Platinum Group Metals Association (IPA) represents the worldwide leading mining, production and fabrication companies in the global platinum group metals (PGMs) industry. An Industry-wide challenge with platinum in the workplace is the allergenic nature of some platinum compounds; for example Pt (IV) hexachloro and Pt (II) tetrachloro complexes.

As part of a wider program to collaboratively study the occupational hygiene aspects of platinum compounds, the IPA, Health Research Group – Science Task Force (HSRG) would be interested in the development of techniques to quantify, or at least estimate, the concentrations of such compounds in a speciated manner in air samples taken from the workplace. These are taken by drawing air through a membrane filter. See for example www.hse.gov.uk/pubns/mdhs/pdfs/mdhs46-2.pdf. Given the normal sampling used and the current exposure limit, the technique would, as a starting point, be required to distinguish between say the Pt (II) and Pt(IV) chloro compounds mentioned above with only 1 ng of Pt on the filter (typically 15-30mm diameter). It is expected that stabilisation of species represents the major challenge for solution based approaches as elution of the platinum compounds from the filter will generally result in a re-equilibration of any platinum chloro species. Alternatively sensitivity for direct solid speciation is expected to be the major challenge.

You are invited to propose potential techniques capable of addressing this methodological need, which would be practicable to be performed within a reasonably sophisticated Industrial Hygiene analytical laboratory.

The best proposals, which are considered to be most likely to achieve a practical outcome, will receive research funding from the IPA. Initially, you should submit an outline of your proposal covering no more than one side of A4 paper. It should include an indicative research costing. Any successful candidates will then be required to submit a more detailed proposal.

Deadline for proposals: Friday 14th December 2012

If you would like to send a proposal, please send via email to Caroline Braibant - braibant@epmf.be

If you have any technical queries, please contact Peter Ash – ashpw@matthey.com

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Metallomics 2013: 8-11 July – Oviedo, Spain

The 4th International Symposium on Metallomics organised by the Analytical Spectrometry Group will be held in 2013 at the Calatrava Congress Centre in Oviedo, Spain from Monday 8th July to Thursday 11th July.

The meeting will include invited presentations of well-known colleagues trying to cover the entire spectrum of metallomics and oral presentations. Topics include:

  • Metalloproteins and -enzymes
  • Tools for Metallomics
  • Metals in Neurosciences
  • Toxicological and Essential Aspects of Metal Species
  • Metallodrugs
  • Metals for Bioimaging and Nanoscience
  • Plants Metallomics

Special emphasis will be placed on poster sessions, in which preferably young scientists will have the great opportunity to discuss their work in a stimulating and relaxed atmosphere. The poster sessions will include the exhibition of scientific instrumentations and support presented by the world-wide leading suppliers. A number of basic short courses will be also provided.

Important Dates (2013)

  • 10th January – Opening of Abstract Submission and Registration
  • 1st April – Deadline for Abstract Submission
  • 1st May – Notification to Authors about Abstract Acceptance
  • 15th May – Deadline for Early Registration

Contact the Conference Secretary – Jörg Bettmer: secretary@metallomics2013.com / Phone: +34-985103000 (ext 5366) or visit the website for more details.

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HOT articles in Metallomics this October

Take a look below at some wonderful HOT articles we’ve recently published this month in Metallomics. There are papers covering a large variety of fields, including yeast analysis, trace elements in rat retina, and platinum drug bio-distributions. These HOT papers will be free to read for two weeks.

Metallation and mismetallation of iron and manganese proteins in vitro and in vivo: the class I ribonucleotide reductases as a case study
Joseph A. Cotruvo, Jr and JoAnne Stubbe
Metallomics, 2012, 4, 1020-1036
DOI: 10.1039/C2MT20142A

Monitoring the production process of selenized yeast by elemental speciation analysis
Evelyn Rampler ,  Stephan Rose ,  Dominik Wieder ,  Anja Ganner ,  Ilse Dohnal ,  Thomas Dalik ,  Stephan Hann and Gunda Koellensperger
Metallomics, 2012, 4, 1176-1184
DOI: 10.1039/C2MT20138K

Concentration of various trace elements in the rat retina and their distribution in different structures
Marta Ugarte ,  Geoffrey W. Grime ,  Gillian Lord ,  Kalotina Geraki ,  Joanna F. Collingwood ,  Mary E. Finnegan ,  Hannah Farnfield ,  Michael Merchant ,  Melanie J. Bailey ,  Neil I. Ward ,  Peter J. Foster ,  Paul N. Bishop and Neville N. Osborne
Metallomics, 2012, Advance Article
DOI: 10.1039/C2MT20157G

ZIP14 and ZIP8 zinc/bicarbonate symporters in Xenopus oocytes: characterization of metal uptake and inhibition
Daniel W. Nebert ,  Marina Gálvez-Peralta ,  E. Ben Hay ,  Hong Li ,  Elisabet Johansson ,  Chen Yin ,  Bin Wang ,  Lei He and Manoocher Soleimani
Metallomics, 2012, 4, 1218-1225
DOI: 10.1039/C2MT20177A

Getting to the core of platinum drug bio-distributions: the penetration of anti-cancer platinum complexes into spheroid tumour models
Jenny Z. Zhang ,  Nicole S. Bryce ,  Antonio Lanzirotti ,  Catherine K. J. Chen ,  David Paterson ,  Martin D. de Jonge ,  Daryl L. Howard and Trevor W. Hambley
Metallomics, 2012, 4, 1209-1217
DOI: 10.1039/C2MT20168B

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Top ten most accessed Metallomics articles in September

This month sees the following articles in Metallomics that are in the top ten most accessed for September:

Dual-function triazole–pyridine derivatives as inhibitors of metal-induced amyloid-ß aggregation
Michael R. Jones ,  Erin L. Service ,  John R. Thompson ,  Michael C. P. Wang ,  Isaac J. Kimsey ,  Alaina S. DeToma ,  Ayyalusamy Ramamoorthy ,  Mi Hee Lim and Tim Storr
Metallomics, 2012, 4, 910-920
DOI: 10.1039/c2mt20113e

Identifying metalloproteins through X-ray fluorescence mapping and mass spectrometry
Daniel Raimunda ,  Tripti Khare ,  Carol Giometti ,  Stefan Vogt ,  José M. Argüello and Lydia Finney
Metallomics, 2012, 4, 921-927
DOI: 10.1039/c2mt20095c

Siderophore-based detection of Fe(iii) and microbial pathogens
Tengfei Zheng and Elizabeth M. Nolan
Metallomics, 2012, 4, 866-880
DOI: 10.1039/c2mt20082a

Recent developments in ruthenium anticancer drugs
Aviva Levina ,  Anannya Mitra and Peter A. Lay
Metallomics, 2009, 1, 458-470
DOI: 10.1039/b904071d

Advances in metal–carbene complexes as potent anti-cancer agents
Arnaud Gautier and Federico Cisnetti
Metallomics, 2012, 4, 23-32
DOI: 10.1039/c1mt00123j

Metallation and mismetallation of iron and manganese proteins in vitro and in vivo: the class I ribonucleotide reductases as a case study
Joseph A. Cotruvo, Jr and JoAnne Stubbe
Metallomics, 2012, 4, 1020-1036
DOI: 10.1039/c2mt20142a

Arsenic metabolism and thioarsenicals
Kanwal Rehman and Hua Naranmandura
Metallomics, 2012, 4, 881-892
DOI: 10.1039/c2mt00181k

The effect of sodium thiosulfate on the metabolism of cis-platin in human plasma in vitro
Melani Sooriyaarachchi ,  Aru Narendran and Jürgen Gailer
Metallomics, 2012, 4, 960-967
DOI: 10.1039/c2mt20076g

Metal imaging in neurodegenerative diseases
Megan W. Bourassa and Lisa M. Miller
Metallomics, 2012, 4, 721-738
DOI: 10.1039/c2mt20052j

Distinct cellular fates for KP1019 and NAMI-A determined by X-ray fluorescence imaging of single cells
Jade B. Aitken ,  Sumy Antony ,  Claire M. Weekley ,  Barry Lai ,  Leone Spiccia and Hugh H. Harris
Metallomics, 2012, 4, 1051-1056
DOI: 10.1039/c2mt20072d

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to Metallomics? Then why not submit to us today!

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Top Ten most-read Metallomics articles in January

This month sees the following articles in Metallomics that are in the top ten most accessed in January:

Advances in metal-carbene complexes as potent anti-cancer agents 
Arnaud Gautier and Federico Cisnetti  
Metallomics, 2012, 4, 23-32 
DOI: 10.1039/C1MT00123J 

Copper complexes as therapeutic agents 
Clare Duncan and Anthony R. White  
Metallomics, 2012, 4, 127-138 
DOI: 10.1039/C2MT00174H 

Crystal structure of the multicopper oxidase from the pathogenic bacterium Campylobacter jejuni CGUG11284: characterization of a metallo-oxidase 
Catarina S. Silva ,  Paulo Durão ,  Amanda Fillat ,  Peter F. Lindley ,  Lígia O. Martins and Isabel Bento  
Metallomics, 2012, 4, 37-47 
DOI: 10.1039/C1MT00156F 

DNA, protein binding, cytotoxicity, cellular uptake and antibacterial activities of new palladium(ii) complexes of thiosemicarbazone ligands: effects of substitution on biological activity 
P. Kalaivani ,  R. Prabhakaran ,  F. Dallemer ,  P. Poornima ,  E. Vaishnavi ,  E. Ramachandran ,  V. Vijaya Padma ,  R. Renganathan and K. Natarajan  
Metallomics, 2012, 4, 101-113 
DOI: 10.1039/C1MT00144B 

Recent developments in ruthenium anticancer drugs 
Aviva Levina ,  Anannya Mitra and Peter A. Lay  
Metallomics, 2009, 1, 458-470 
DOI: 10.1039/B904071D 

Aluminium, iron and copper in human brain tissues donated to the medical research council’s cognitive function and ageing study 
Emily House ,  Margaret Esiri ,  Gill Forster ,  Paul G Ince and Christopher Exley  
Metallomics, 2012, 4, 56-65 
DOI: 10.1039/C1MT00139F 

Interactions of Zn(ii) and Cu(ii) ions with Alzheimer’s amyloid-beta peptide. Metal ion binding, contribution to fibrillization and toxicity 
Vello Tõugu ,  Ann Tiiman and Peep Palumaa  
Metallomics, 2011, 3, 250-261 
DOI: 10.1039/C0MT00073F 

Copper toxicity and the origin of bacterial resistance – new insights and applications 
Christopher L. Dupont ,  Gregor Grass and Christopher Rensing  
Metallomics, 2011, 3, 1109-1118 
DOI: 10.1039/C1MT00107H 

Recent advances into vanadyl, vanadate and decavanadate interactions with actin 
S. Ramos ,  J. J. G. Moura and M. Aureliano  
Metallomics, 2012, 4, 16-22 
DOI: 10.1039/C1MT00124H

The biological occurrence and trafficking of Cobalt
 
Sachi Okamoto and Lindsay D. Eltis  
Metallomics, 2011, 3, 963-970 
DOI: 10.1039/C1MT00056J 

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to Metallomics?  Then why not submit to us today!

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Top Ten most-read Metallomics articles in December

This month sees the following articles in Metallomics that are in the top ten most accessed in December:

Interactions of Zn(ii) and Cu(ii) ions with Alzheimer’s amyloid-beta peptide. Metal ion binding, contribution to fibrillization and toxicity 
Vello Tõugu, Ann Tiiman and Peep Palumaa 
Metallomics, 2011, 3, 250-261 
DOI: 10.1039/C0MT00073F 

DNA binding and nucleolytic properties of Cu(ii) complexes of salicylaldehyde semicarbazones 
Wan Yen Lee, Yaw Kai Yan, Peter Peng Foo Lee, Shiow Jin Tan and Kok Hwa Lim 
Metallomics, 2012, Advance Article 
DOI: 10.1039/C1MT00147G 

Recent developments in ruthenium anticancer drugs 
Aviva Levina, Anannya Mitra and Peter A. Lay 
Metallomics, 2009, 1, 458-470 
DOI: 10.1039/B904071D 

Gold compounds as therapeutic agents for human diseases 
Susan J. Berners-Price and Aleksandra Filipovska 
Metallomics, 2011, 3, 863-873 
DOI:
10.1039/C1MT00062D 

Exploring the microbial metalloproteome using MIRAGE 
Ana-Maria Sevcenco, Martijn W. H. Pinkse, Hubert Th. Wolterbeek, Peter D. E. M. Verhaert, Wilfred R. Hagen and Peter-Leon Hagedoorn 
Metallomics, 2011, 3, 1324-1330 
DOI: 10.1039/C1MT00154J 

Chromium interactions in plants: current status and future strategies 
Arun Kumar Shanker, Maduraimuthu Djanaguiraman and Bandi Venkateswarlu 
Metallomics, 2009, 1, 375-383 
DOI: 10.1039/B904571F 

Bacterial ATP-driven transporters of transition metals: physiological roles, mechanisms of action, and roles in bacterial virulence
 
Joshua S. Klein and Oded Lewinson 
Metallomics, 2011, 3, 1098-1108 
DOI: 10.1039/C1MT00073J 

The oxidative stress of zinc deficiency 
David J. Eide 
Metallomics, 2011, 3, 1124-1129 
DOI: 10.1039/C1MT00064K 

The Potential Application of Iron Chelators for the Treatment of Neurodegenerative Diseases
 
Robert C. Hider, Sourav Roy, Yong Min Ma, Xiao Le Kong and Jane Preston 
Metallomics, 2011, 3, 239-249
DOI: 10.1039/C0MT00087F 

Subcellular localization of a fluorescent derivative of CuII(atsm) offers insight into the neuroprotective action of CuII(atsm) 
Katherine Ann Price, Peter J. Crouch, SinChun Lim, Brett M. Paterson, Jeffrey R. Liddell, Paul S. Donnelly and Anthony R. White 
Metallomics, 2011, 3, 1280-1290 
DOI: 10.1039/C1MT00092F 

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to Metallomics?  Then why not submit to us today!.

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Top Ten most-read Metallomics articles in November

This month sees the following articles in Metallomics that are in the top ten most accessed in November:

Bacterial ATP-driven transporters of transition metals: physiological roles, mechanisms of action, and roles in bacterial virulence 
Joshua S. Klein and Oded Lewinson 
Metallomics, 2011, 3, 1098-1108 
DOI: 10.1039/C1MT00073J 

Recent developments in ruthenium anticancer drugs 
Aviva Levina, Anannya Mitra and Peter A. Lay 
Metallomics, 2009, 1, 458-470 
DOI: 10.1039/B904071D 

Metabolomics and its application to studying metal toxicity 
Sean C. Booth, Matthew L. Workentine, Aalim M. Weljie and Raymond J. Turner 
Metallomics, 2011, 3, 1142-1152 
DOI: 10.1039/C1MT00070E 

Interactions of Zn(ii) and Cu(ii) ions with Alzheimer’s amyloid-beta peptide. Metal ion binding, contribution to fibrillization and toxicity 
Vello Tõugu, Ann Tiiman and Peep Palumaa 
Metallomics, 2011, 3, 250-261 
DOI: 10.1039/C0MT00073F 

The oxidative stress of zinc deficiency 
David J. Eide 
Metallomics, 2011, 3, 1124-1129 
DOI: 10.1039/C1MT00064K 

Copper toxicity and the origin of bacterial resistance- new insights and applications
Christopher L. Dupont, Gregor Grass and Christopher Rensing 
Metallomics, 2011, 3, 1109-1118 
DOI: 10.1039/C1MT00107H 

The “magic numbers” of metallothionein 
Duncan E. K. Sutherland and Martin J. Stillman 
Metallomics, 2011, 3, 444-463 
DOI: 10.1039/C0MT00102C 

Role of metal ions in aggregation of intrinsically disordered proteins in neurodegenerative diseases 
Leonid Breydo and Vladimir N. Uversky 
Metallomics, 2011, 3, 1163-1180 
DOI: 10.1039/C1MT00106J 

DNA, protein binding, cytotoxicity, cellular uptake and antibacterial activities of new palladium(ii) complexes of thiosemicarbazone ligands: effects of substitution on biological activity 
P. Kalaivani, R. Prabhakaran, F. Dallemer, P. Poornima, E. Vaishnavi, E. Ramachandran, V. Vijaya Padma, R. Renganathan and K. Natarajan 
Metallomics, 2012, Advance Article 
DOI: 10.1039/C1MT00144B 

Genetic and epigenetic effects of environmental arsenicals 
Toby G. Rossman and Catherine B. Klein 
Metallomics, 2011, 3, 1135-1141 
DOI: 10.1039/C1MT00074H 

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to Metallomics?  Then why not submit to us today!.

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Top Ten most-read Metallomics articles in October

This month sees the following articles in Metallomics that are in the top ten most accessed in October:

Inhibition of transcription by platinum antitumor compounds
Ryan C. Todd and Stephen J. Lippard
Metallomics, 2009, 1, 280-291
DOI: 10.1039/b907567d

Copper toxicity and the origin of bacterial resistance—new insights and applications
Christopher L. Dupont, Gregor Grass and Christopher Rensing
Metallomics, 2011, 3, 1109-1118
DOI: 10.1039/c1mt00107h

Recent developments in ruthenium anticancer drugs
Aviva Levina, Anannya Mitra and Peter A. Lay
Metallomics, 2009, 1, 458-470
DOI: 10.1039/b904071d

Disorders associated with systemic or local iron overload: from pathophysiology to clinical practice
Giada Sebastiani and Kostas Pantopoulos
Metallomics, 2011, 3, 971-986
DOI: 10.1039/c1mt00082a

Gold compounds as therapeutic agents for human diseases
Susan J. Berners-Price and Aleksandra Filipovska
Metallomics, 2011, 3, 863-873
DOI: 10.1039/c1mt00062d

Speciation of oxaliplatin adducts with DNA nucleotides
Aref Zayed, George D. D. Jones, Helen J. Reid, Tamer Shoeib, Sarah E. Taylor, Anne L. Thomas, Joanna P. Wood and Barry L. Sharp
Metallomics, 2011, 3, 991-1000
DOI: 10.1039/c1mt00041a

The regulatory role of heme in neurons
Andrew G. Smith, Emma Lloyd Raven and Tatyana Chernova
Metallomics, 2011, 3, 955-962
DOI: 10.1039/c1mt00085c

Genetic and epigenetic effects of environmental arsenicals
Toby G. Rossman and Catherine B. Klein
Metallomics, 2011, 3, 1135-1141
DOI: 10.1039/c1mt00074h

Cysteine proteases as targets for metal-based drugs
Simon P. Fricker
Metallomics, 2010, 2, 366-377
DOI: 10.1039/b924677k

Combined application of a laser ablation-ICP-MS assay for screening and ESI-FTICR-MS for identification of a Cd-binding protein in Spinacia oleracea L. after exposure to Cd
Aleksandra Polatajko, Ingo Feldmann, Heiko Hayen and Norbert Jakubowski
Metallomics, 2011, 3, 1001-1008
DOI: 10.1039/c1mt00051a


Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to Metallomics?  Then why not submit to us today!.

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