Metallomics Editorial Board Member, Yasumitsu Ogra (Chiba University, Japan) selects his Top 5 articles from recent issues of Metallomics.
Yasumitsu Ogra is professor of the Department of Toxicology and Environmental Health, Chiba University, Chiba, Japan. His current research is devoted to toxicometallomics and the elucidation of mechanisms underlying physiological and toxicological effects of metals and metalloids.
Read Yasumitsu Ogra’s Editor’s Choice selection via the links below – all articles are free to access for the next 4 weeks!
Shikha Verma et al., Metallomics, 2016, 8, 344, DOI:10.1039/C5MT00277J
The authors identify a novel arsenic methyltransferase from a soil fungus. The methyltransferase mainly converts inorganic arsenicals such as arsenite arsenate to volatile methylated arsenic species. The observation may be useful for bioremediation of arsenic-contaminated soil.
J. E. J. Hardyman et al., Metallomics, 2016, 8, 337, DOI:10.1039/C5MT00305A
Metal-responsive transcription factor 1 (MTF-1) is known as a transcription factor sensing an intracellular zinc concentration. In this paper, some gene expressions are indirectly controlled by MTF-1 via the expressions of metallothioneins and an efflux transporter of zinc (ZnT-1) which are directly regulated by MTF-1.
Vincent Perrot et al., Metallomics, 2016, 8, 170, DOI:10.1039/C5MT00286A
The authors reveal the metabolism of methylmercury in marine mammals by the analysis of precise isotopic ratio of mercury. This approach is unique to clarify the detoxification of methylmercury.
Dominic J. Hare et al., Metallomics, 2016, 8, 156, DOI:10.1039/C5MT00288E
The authors demonstrate the multi-elemental imaging in C. elegans by X-ray fluorescence microscopy. This technique is expected to be widely applicable for biology in metals.
Cheng-Yu Tsai et al., Metallomics, 2015, 7, 1477, DOI:10.1039/C5MT00131E
There are two copper influx transporters in mammalian cells, CTR1 and CTR2. The authors clearly show that the defection of CTR1 reduces the stability of CTR2 protein. This is the first paper revealing the direct interaction between two copper influxers involved in copper homeostasis.