Metallomics Issue 1 NOW online!

The end of the year is just the right time for us to enjoy the Issue 1 of Metallomics!

Artistic design by Heidi Cartwright from an original photograph of the human choroid plexus by Katherine Davies

We have four beautiful covers featuring outstanding research coming from all over the world. Our original outside front cover shows the work of Kay Double from Australia, who studied copper regulation in the human brain. Copper and copper transporters were localised in the brain by using inductively coupled plasma-mass spectrometry. This work provides new insights into the mechanisms by which copper levels are altered in the brain leading to neurological diseases.

Localization of copper and copper transporters in the human brain
Katherine M. Davies ,  Dominic J. Hare ,  Veronica Cottam ,  Nicholas Chen ,  Leon Hilgers ,  Glenda Halliday ,  Julian F. B. Mercer and Kay L. Double
Metallomics, 2013,5, 43-51
DOI: 10.1039/C2MT20151H

Images of dividing cells

This bright and colorful inside front cover gives us a snapshot of a study from the Georgia Institute of Technology, USA. Christoph Fahrni and co-workers examined the distribution of trace metals such as metal, zinc and iron in mouse fibroblast cells during cell division. Using X-ray fluorescence microscopy, they suggest the mechanisms of inheritance of these metals.

Selenium and sulphur in sunflower leaves by LA-ICP-MS

Subcellular redistribution and mitotic inheritance of transition metals in proliferating mouse fibroblast cells
Reagan McRae ,  Barry Lai and Christoph J. Fahrni
Metallomics, 2013,5, 52-61
DOI: 10.1039/C2MT20176C

Coming from South America is the work of Marco Aurelio Zezzi Arruda, represented in our inside back cover. His team developed a qualitative and quantitative method to map selenium and sulphur in sunflower leaves, using the recently developed laser ablation imaging mass spectrometry (LA-ICP-MS) technique.

Laser ablation (imaging) for mapping and determining Se and S in sunflower leaves
Marcelo Anselmo Oseas da Silva and Marco Aurelio Zezzi Arruda
Metallomics, 2013,5, 62-67
DOI: 10.1039/C2MT20154B

Finally, our cheerful outside back cover features a minireview from Atlanta, USA, written by Jenny Yang and colleagues. The authors explain the concept of “Calciomics”, outlining the most recent approaches used to identify calcium-binding proteins and to understand how they interact with their targets.

Calcium binding proteins in biological systems

Calciomics: integrative studies of Ca2+-binding proteins and their interactomes in biological systems
Yubin Zhou ,  Shenghui Xue and Jenny J. Yang
Metallomics, 2013,5, 29-42
DOI: 10.1039/C2MT20009K

Along with these new covers, Issue 1 presents a couple of HOT papers for you free to read until January 10th. Take a look now by accessing the links below. And don’t forget to check out our Editorial on the recent successes of Metallomics.

Molecular strategies of microbial iron assimilation: from high-affinity complexes to cofactor assembly systems
Marcus Miethke
Metallomics, 2013, Advance Article
DOI: 10.1039/C2MT20193C

Pseudomonas putida KT2440 response to nickel or cobalt induced stress by quantitative proteomics
Prasun Ray ,  Vincent Girard ,  Manon Gault ,  Claudette Job ,  Marc Bonneu ,  Marie-Andrée Mandrand-Berthelot ,  Surya S. Singh ,  Dominique Job and Agnès Rodrigue
Metallomics, 2013, Advance Article
DOI: 10.1039/C2MT20147J

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