Issue 8 now online

Metal imaging in neurodegenerative diseases

Front cover: Bourassa and Miller, Metallomics, 2012,4, 721-738

The latest issue of Metallomics is now online, with not one, not two but four covers:

Our colourful front cover features an article from Lisa Miller of the National Synchrotron Light Source at Brookhaven National Laboratory (New York, USA) and her Ph.D. student at Stony Brook University, Megan Bourassa. Their Critical Review highlights the advances in neurodegenerative disease research facilitated by metal imaging techniques.

Critical Review: Metal imaging in neurodegenerative diseases
Megan W. Bourassa and Lisa M. Miller
Metallomics, 2012, 4, 721-738
DOI: 10.1039/C2MT20052J

The inside front cover comes from Martin Stillman and colleagues at Western University, London, Canada. They look at the effects of metal and ring periphery substitution in the Isd protein system involved in heme transport in the pathogenic bacterium Staphylococcus aureus.

Insight into blocking heme transfer by exploiting molecular interactions in the core Isd heme transporters IsdA-NEAT, IsdC-NEAT, and IsdE of Staphylococcus aureus
Michael T. Tiedemann,  Tyler B. J. Pinter and Martin J. Stillman
Metallomics, 2012, 4, 751-760
DOI: 10.1039/C2MT20067H

Blocking heme transfer in Staphylococcus aureus

Inside front cover: Tiedemann et al., Metallomics, 2012, 4, 751-760

On the inside back cover, a paper from Christophe Biot and co-workers at the University of Lille, who used two ruthenocenic bioprobes to study the mechanism of the antimalarial drug candidate ferroquine.

Opening up the advantages of the ruthenocenic bioprobes of ferroquine: distribution and localization in Plasmodium falciparum-infected erythrocytes
Christophe Biot,  Faustine Dubar,  Jamal Khalife and Christian Slomianny
Metallomics, 2012, 4, 780-783
DOI: 10.1039/C2MT20063E

And finally, on the outside back cover, Ruth Valentine and colleagues at Newcastle University present new information on the functional activity of the zinc transporter ZnT10.

Efflux function, tissue-specific expression and intracellular trafficking of the Zn transporter ZnT10 indicate roles in adult Zn homeostasis
Helen J. Bosomworth,  Jared K. Thornton,  Lisa J. Coneyworth,  Dianne Ford and Ruth A. Valentine
Metallomics, 2012, 4, 771-779
DOI: 10.1039/C2MT20088K

All these cover articles will be free to access for 6 weeks – enjoy!


Metallomics, 2012, Issue 8, back covers

Back covers: Biot et al. (L) and Bosomworth et al. (R)

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