Nanopore analysis has become an emerging technique for study of the conformation of proteins and protein/protein interactions. Besnik Krasniqi and Jeremy S. Lee from the University of Saskatchewan in Canada have been studying the effects of different buffers such as HEPES, TRIS and EDTA on nanopore analysis.
Their paper will be free to access for 2 weeks, so click through and read more here.
The importance of adding EDTA for the nanopore analysis of proteins
Besnik Krasniqi and Jeremy S. Lee
Metallomics, 2012, Advance Article