In this HOT article from Seiichiro Himeno and colleagues from Tokushima Bunri University, Japan, the role of metal transporters in the absorption of Cd2+ and Mn2+ into proximal tubule cells of the kidney is being studied. The unfortunate effects of chronic exposure to cadmium is the preferential accumulation of cadmium in the kidney which can lead to nephrotoxicity.
Roles of ZIP8, ZIP14, and DMT1 in transport of cadmium and manganese in mouse kidney proximal tubule cells
Hitomi Fujishiro, Yu Yano, Yukina Takada, Maya Tanihara and Seiichiro Himeno
Metallomics, 2012, Advance Article
DOI: 10.1039/C2MT20024D
