The latest issue of Metallomics in now available online for you to browse. Featuring nucleic acid chemistry, pharmaceuticals, metabolomics, metals in plants and much more!
On the front cover is research from Korea by Hyosun Lee and Seog K. Kim from Kyungpook National University and Yeungnam University, respectively, who along with their colleagues have studied the binding modes and photo-induced DNA cleavage mechanisms of porphyrins.
Photo-induced DNA scission by Cu(II)-meso-tetrakis(n-N-methylpyridiniumyl)porphyrins (n = 2, 3, 4) and their binding modes to supercoiled DNA
Nataraj Chitrapriya, Jongjin Park, Wei Wang, Hyosun Lee and Seog K. Kim
Metallomics, 2012, Advance Article
DOI: 10.1039/C2MT20015E
We travel to Brazil for our inside front cover this month, with an image from Frédéric Frézard from Universidade Federal de Minas Gerais. Together with co-workers he has been looking at antimonial drugs, drugs which contain antimony, in the treatment of leishmaniasis. This is a type of parasitic disease caused by kinetoplastid protozoa which belong to the genus Leishmania.
Greater binding affinity of trivalent antimony to a CCCH zinc finger domain compared to a CCHC domain of kinetoplastid proteins
Frédéric Frézard, Heveline Silva, Adriano Monteiro de Castro Pimenta, Nicholas Farrell and Cynthia Demicheli
Metallomics, 2012, Advance Article
DOI: 10.1039/C2MT00176D

Metals in Biology Gordon Research Conference
These cover articles will be free to access for 6 weeks, so why not click through and take a look.
This month we also have a lovely Editorial by Richard H. Holm and Michael J. Maroney from the 2012 Metals in Biology Gordon Research Conference which was held January 22–27, in Ventura, CA, USA. As well as the scientific program, the conference celebrated the 50th anniversary of the very first meeting.
50 Years of Metals in Biology: the Gordon Research Conference
Metallomics, 2012, Advance Article
DOI: 10.1039/C2MT90017C
Issue 5 also has a minireview by Bei Wu and J. Sabine Becker from the Central Division of Analytical Chemistry, Forschungszentrum Jülich, Germany. In it they cover the emerging techniques for elemental imaging and speciation analysis that allows researchers to obtain increasing knowledge of elemental distribution and availabilities in plants.
Imaging techniques for elements and element species in plant science
Bei Wu and J. Sabine Becker
Metallomics, 2012, Advance Article
DOI: 10.1039/C2MT00002D
Finally, we also have a HOT article for you to read. Hugues Preud’homme and colleagues from the Université de Pau et des Pays de l’Adour, France, have studied selenium-rich yeasts as there is growing evidence of the superiority of organic forms of selenium over selenate or selenite in terms of bioaccessibility.
Large-scale identification of selenium metabolites by online size-exclusion-reversed phase liquid chromatography with combined inductively coupled plasma (ICP-MS) and electrospray ionization linear trap-Orbitrap mass spectrometry (ESI-MSn)
Hugues Preud’homme, Johann Far, Sandra Gil-Casal and Ryszard Lobinski
Metallomics, 2012, Advance Article
DOI: 10.1039/C2MT00172A