This new and exciting issue comes with two reviews.
The first one by Paul Leeson and collegues on the impact of ion class and the time on the properties of oral drugs and the second one by Peter Kovacic and Ratnasamy Somanathan on the mechanisms of aromatic primary amines and the influence on the physiological activity.
The issue also contains six vibrant concise articles that bring you the best medicinal chemistry research.
From 2D and 3D activity landscape representations to imaging contrast agents. For those of you who are more synthetic medchems you can find articles on the synthesis and biological activities of AA-Trp-Trp-OBzl and isoquinolones. We close the issue with a study of activation energies and their influence in the stability of drugs and a final article on HIV-integrase inhibitors.
What do you think? We would like to receive your feedback on the new RSC medicinal chemistry journal MedChemComm!