Top ten most accessed articles in October

This month sees the following articles in MedChemComm that are in the top ten most accessed:-

Silver nanoparticles – the real “silver bullet” in clinical medicine? 
Kenneth K. Y. Wong and Xuelai Liu 
Med. Chem. Commun., 2010, 1, 125-131, DOI: 10.1039/C0MD00069H, Review  

Targeting epigenetic modifiers: Inhibitors of histone methyltransferases 
Elisabeth-Maria Bissinger, Ralf Heinke, Wolfgang Sippl and Manfred Jung 
Med. Chem. Commun., 2010, 1, 114-124, DOI: 10.1039/C0MD00062K, Review  

Chemical space as a source for new drugs 
Jean-Louis Reymond, Ruud van Deursen, Lorenz C. Blum and Lars Ruddigkeit 
Med. Chem. Commun., 2010, 1, 30-38, DOI: 10.1039/C0MD00020E, Review  

Small molecule modulation of stem cells in regenerative medicine: recent applications and future direction 
Timothy E. Allsopp, Mark E. Bunnage and Paul V. Fish 
Med. Chem. Commun., 2010, 1, 16-29, DOI: 10.1039/C0MD00055H, Review  

Boronic acids in medicinal chemistry: anticancer, antibacterial and antiviral applications 
Paul C. Trippier and Christopher McGuigan 
Med. Chem. Commun., 2010, 1, 183-198, DOI: 10.1039/C0MD00119H, Review  

Discovery of the highly potent PI3K/mTOR dual inhibitor PF-04691502 through structure based drug design 
Hengmiao Cheng, Shubha Bagrodia, Simon Bailey, Martin Edwards, Jacqui Hoffman, Qiyue Hu, Robert Kania, Daniel R. Knighton, Matthew A. Marx, Sacha Ninkovic, Shaoxian Sun and Eric Zhang 
Med. Chem. Commun., 2010, 1, 139-144, DOI: 10.1039/C0MD00072H, Concise Article 

Data-mining patent literature for novel chemical reagents for use in medicinal chemistry design 
Jason G. Kettle, Richard A. Ward and Ed Griffen 
Med. Chem. Commun., 2010, 1, 331-338, DOI: 10.1039/C0MD00148A, Concise Article  

Design, synthesis, and structure-activity relationships of indole-3-carboxamides as novel water soluble cannabinoid CB1 receptor agonists 
Julia M. Adam, Jim Cairns, Wilson Caulfield, Phillip Cowley, Iain Cumming, Morag Easson, Darren Edwards, Morag Ferguson, Richard Goodwin, Fiona Jeremiah, Takao Kiyoi, Ashvin Mistry, Elizabeth Moir, Richard Morphy, Jason Tierney, Mark York, James Baker, Jean E. Cottney, Andrea K. Houghton, Paul J. Westwood and Glenn Walker 
Med. Chem. Commun., 2010, 1, 54-60, DOI: 10.1039/C0MD00022A, Concise Article  

Aromatic chloride to nitrile transformation: medicinal and synthetic chemistry 
Lyn H. Jones, Nicholas W. Summerhill, Nigel A. Swain and James E. Mills 
Med. Chem. Commun., 2010, 1, 309-318, DOI: 10.1039/C0MD00135J, Review  

Selective inhibition of EGFR and VEGFR2 tyrosine kinases controlled by a boronic acid substituent on 4-anilinoquinazolines 
Hiroyuki Nakamura, Ryoji Horikoshi, Taikou Usui and Hyun Seung Ban 
Med. Chem. Commun., 2010, 1, 282-286, DOI: 10.1039/C0MD00115E, Concise Article 

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to MedChemComm? Then why not submit to us today or alternatively email us your suggestions.
 

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