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Introducing Molecular Omics

Molecular Omics

In 2018 Molecular BioSystems is refocusing its scope and relaunching as Molecular Omics which will focus on the –omics sciences.

Molecular Omics will publish molecular level experimental and bioinformatics research in the -omics sciences, including genomics, proteomics, transcriptomics and metabolomics. We will also welcome multidisciplinary papers presenting studies combining different types of omics, or the interface of omics and other fields such as systems biology or chemical biology.
For more information visit our website.

Now open for submissions
Molecular Omics will only accept articles which are of significant importance to their field; either fundamental research which significantly increases understanding, or research which demonstrates clear functional benefits.
In this journal we will bring the Royal Society of Chemistry’s reputation for:

  • high impact journals in areas which interface with chemistry
  • great service and times to publication
  • global reach with offices in key countries around the world

To submit, please visit: https://mc.manuscriptcentral.com/mo.

Keep in touch
If you are interested in the work that we will publish in Molecular Omics, curious about new developments in our scope, or considering the journal for your own work, then complete our form now to receive carefully selected alerts.  Sign up for e-alerts

 

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HUPO 2017 Conference

Molecular BioSystems is pleased to support the 16th Human Proteome Organization World Congress 2017.  It will be held at The Convention Centre Dublin (The CCD) from the 17th – 21st September 2017.

The conference provides a forum to present, discuss and advance proteomic research. The programme aims to consolidate existing knowledge and increase awareness of advances in the field.

This year the speakers include:

  • Leroy E. Hood: Systems Medicine, Big Data and Scientific Wellness: Transforming Healthcare—A Personal View
  • Ruedi Aebersold: The Proteome in Context
  • Ben Davis: Sugars and Proteins: Towards a Synthetic Biology
  • Albert Heck: Probing Biopharmaceutical Proteins and Protein Assemblies by Hybrid Mass Spectrometry Approaches
  • Matthias Mann: Proteomics for Signaling and Clinical Studies
  • Henry Rodriguez: Omics Convergence in Cancer Research: Advances in Precision Medicine
  • Pauline Rudd: Deciphering the Glycoproteome: a Small Step Towards Understanding the Complexity of Biological Systems
  • Matthias Uhlen: The Human Protein Atlas – Implications for Human Biology, Drug Development and Precision Medicine
  • Jenny van Eyk: Changing the Course and Impact of Chronic Disease: Personalizing Medicine
  • Atul Butte: Translating a Trillion Points of Data into Therapies, Diagnostics, and New Insights into Disease

The full programme can be found here: http://hupo2017.ie/programme/

For more information and to register please visit the website.

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11th annual meeting of the Japanese Society for Chemical Biology

The 11th annual meeting of the Japanese Society for Chemical Biology was held in Kyoto, Japan from the 15 – 17th June 2016.  Molecular BioSystems was pleased to award two poster prizes.

Congratulations to the winners:

Dr. Mizuki Endo (University of Tokyo): Light-induced protein oligomerization system for the optogenetic control of neurite outgrowth direction in living animal

Mr. Kazuma Mori (Osaka University): Clarification the Function of GLUT4 N-glycan in the Intracellular Trafficking Based on PYP-tag Technology and New Long-wavelength Fluorescent Probes

The winners were presented with their prizes by committe chair Prof. Hiroshi Sugiyama (Kyoto University).

Prof Sugiyama (left) presents Dr. Mizuki Endo (right) with his prize

Mr. Kazuma Mori (far left) and Prof. Hiroshi Sugiyama (far right)

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What are your colleagues reading in Molecular BioSystems?

The articles below are some of the most read Molecular BioSystems articles in January, February and March 2016.

Isothermal amplified detection of DNA and RNA
Lei Yan, Jie Zhou, Yue Zheng, Adam S. Gamson, Benjamin T. Roembke, Shizuka Nakayama and Herman O. Sintim
DOI: 10.1039/C3MB70304E, Review Article

Why phosphoproteomics is still a challenge
Fiorella A. Solari, Margherita Dell’Aica, Albert Sickmann and René P. Zahedi
DOI: 10.1039/C5MB00024F, Opinion

Exploration of the HIF-1α/p300 interface using peptide and Adhiron phage display technologies
Hannah F. Kyle, Kate F. Wickson, Jonathan Stott, George M. Burslem, Alexander L. Breeze, Christian Tiede, Darren C. Tomlinson, Stuart L. Warriner, Adam Nelson, Andrew J. Wilson and Thomas A. Edwards
DOI: 10.1039/C5MB00284B, Paper

PLS/OPLS models in metabolomics: the impact of permutation of dataset rows on the K-fold cross-validation quality parameters
Mohamed N. Triba, Laurence Le Moyec, Roland Amathieu, Corentine Goossens, Nadia Bouchemal, Pierre Nahon, Douglas N. Rutledge and Philippe Savarin
DOI: 10.1039/C4MB00414K, Opinion

The PI3K/AKT/mTOR interactive pathway
Tulin Ersahin, Nurcan Tuncbag and Rengul Cetin-Atalay
DOI: 10.1039/C5MB00101C, Paper

Trials and tribulations of ‘omics data analysis: assessing quality of SIMCA-based multivariate models using examples from pulmonary medicine
Åsa M. Wheelock and Craig E. Wheelock
DOI: 10.1039/C3MB70194H, Opinion

The transcriptome of Euglena gracilis reveals unexpected metabolic capabilities for carbohydrate and natural product biochemistry
Ellis C. O’Neill, Martin Trick, Lionel Hill, Martin Rejzek, Renata G. Dusi, Chris J. Hamilton, Paul V. Zimba, Bernard Henrissat and Robert A. Field
DOI: 10.1039/C5MB00319A, Paper

Bridging the layers: towards integration of signal transduction, regulation and metabolism into mathematical models
Emanuel Gonçalves, Joachim Bucher, Anke Ryll, Jens Niklas, Klaus Mauch, Steffen Klamt, Miguel Rocha and Julio Saez-Rodriguez
DOI: 10.1039/C3MB25489E, Review Article

Metabolomic analysis of riboswitch containing E. coli recombinant expression system
Howbeer Muhamadali, Yun Xu, Rosa Morra, Drupad K. Trivedi, Nicholas J. W. Rattray, Neil Dixon and Royston Goodacre
DOI: 10.1039/C5MB00624D, Paper

Mechanism of action-based classification of antibiotics using high-content bacterial image analysis
Kelly C. Peach, Walter M. Bray, Dustin Winslow, Peter F. Linington and Roger G. Linington
DOI: 10.1039/C3MB70027E, Paper

(more…)

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What are your colleagues reading in Molecular BioSystems?

The articles below are the most read Molecular BioSystems articles in July, August and September 2015.

Isothermal amplified detection of DNA and RNA
Lei Yan, Jie Zhou, Yue Zheng, Adam S. Gamson, Benjamin T. Roembke, Shizuka Nakayama and Herman O. Sintim
DOI: 10.1039/C3MB70304E, Review Article

Bridging the layers: towards integration of signal transduction, regulation and metabolism into mathematical models
Emanuel Gonçalves, Joachim Bucher, Anke Ryll, Jens Niklas, Klaus Mauch, Steffen Klamt, Miguel Rocha and Julio Saez-Rodriguez
DOI: 10.1039/C3MB25489E, Review Article

Why phosphoproteomics is still a challenge
Fiorella A. Solari, Margherita Dell’Aica, Albert Sickmann and René P. Zahedi
DOI: 10.1039/C5MB00024F, Opinion

Fatty acid biosynthesis revisited: structure elucidation and metabolic engineering
Joris Beld, D. John Lee and Michael D. Burkart
DOI: 10.1039/C4MB00443D, Review Article

Mechanism of action-based classification of antibiotics using high-content bacterial image analysis
Kelly C. Peach, Walter M. Bray, Dustin Winslow, Peter F. Linington and Roger G. Linington
DOI: 10.1039/C3MB70027E, Paper

Differential protein profile in sexed bovine semen: shotgun proteomics investigation
Michele De Canio, Alessio Soggiu, Cristian Piras, Luigi Bonizzi, Andrea Galli, Andrea Urbani and Paola Roncada
DOI: 10.1039/C3MB70306A, Paper

Connecting gene expression data from connectivity map and in silico target predictions for small molecule mechanism-of-action analysis
Aakash Chavan Ravindranath, Nolen Perualila-Tan, Adetayo Kasim, Georgios Drakakis, Sonia Liggi, Suzanne C. Brewerton, Daniel Mason, Michael J. Bodkin, David A. Evans, Aditya Bhagwat, Willem Talloen, Hinrich W. H. Göhlmann, QSTAR Consortium, Ziv Shkedy and Andreas Bender
DOI: 10.1039/C4MB00328D, Paper

NMR- and MS-based metabolomics: various organ responses following naphthalene intervention
Yee Soon Ling, Hao-Jan Liang, Meng-Hsuan Chung, Ming-Huan Lin and Ching-Yu Lin
DOI: 10.1039/C4MB00090K, Paper

Multifunctional polymeric micelles with folate-mediated cancer cell targeting and pH-triggered drug releasing properties for active intracellular drug delivery
Younsoo Bae, Woo-Dong Jang, Nobuhiro Nishiyama, Shigeto Fukushima and Kazunori Kataoka
DOI: 10.1039/B500266D, Paper

Development of novel assays for lignin degradation: comparative analysis of bacterial and fungal lignin degraders
Mark Ahmad, Charles R. Taylor, David Pink, Kerry Burton, Daniel Eastwood, Gary D. Bending and Timothy D. H. Bugg
DOI: 10.1039/B908966G, Paper

(more…)

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Poster Prize Winners at Biorelevant Chemistry Symposium

We were please to present Poster Prizes at the 9th Symposium on Biorelevant Chemistry.

Congratulations to the winners:

  • Ryo Negshi (Tokyo University of Agriculture and Technology)
  • Yuta Niwa (Tokyo University of Agriculture and Technology)
  • Haruka Iki (University of Tokyo)
  • Hashiru Negishi (Tokyo Institute of Technology)
  • Takuma Sueoka (University of Tokyo)

Organized by the Chemical Society of Japan, the Biorelevant Chemistry Symposium took place from 10-12th Sept in Kumamoto, Japan.

From left to right: Professor Rie Wakabayashi (Poster award committee co-chair), Professor Hiroyuki Asanuma (Poster award committee chair), Ryo Negshi, Yuta Niwa, Haruka Iki, Hashiru Negishi, Takuma Sueoka, Professor Masahiro Takagi (Chair of the Division of Biotechnology, Chemical Society of Japan), Professor Itaru Hamachi (Vice-Chair of the Division of Biofunctional Chemistry, Chemical Society of Japan)

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Smorgasbord of chemical blueprints located in plain pond algae

Euglena-gracilis

The pond algae Euglena gracilis has a surprising wealth of metabolic pathways for unexpected natural products, new research shows. Genes from this common single-celled organism could therefore be manipulated to synthesise a host of unusual, and potentially useful, compounds.

Euglenoids are a group of algae that grow abundantly in nutrient-rich freshwater environments, such as garden ponds. Euglena gracilis is known to produce many nutritional compounds including vitamins A, C and E, essential amino acids and polyunsaturated fatty acids. However, sequencing its genome in a bid to unlock these valuable natural products has proved very challenging due to its large size, complexity and incorporation of the unusual nucleotide base J.

Researchers, led by Rob Field at the John Innes Centre in the UK, have tackled this problem by instead looking at Euglena’s transcriptome – the mRNA transcribed from the genome that shows what genes an organism is using at a given time.



Read the full story in Chemistry World

Read the original journal article in Molecular BioSystems –  it is free to access until 15 October 2015

The transcriptome of Euglena gracilis reveals unexpected metabolic capabilities for carbohydrate and natural product biochemistry

Ellis C. O’Neill, Martin Trick, Lionel Hill, Martin Rejzek, Renata G. Dusi, Chris J. Hamilton, Paul V. Zimba, Bernard Henrissat and Robert A. Field.
Mol. BioSyst., 2015, Advance Article
DOI: 10.1039/C5MB00319A, Paper
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