What are your colleagues reading in Molecular BioSystems?

The articles below are some of the most read Molecular BioSystems articles in April, May and June 2016.

Isothermal amplified detection of DNA and RNA
Lei Yan, Jie Zhou, Yue Zheng, Adam S. Gamson, Benjamin T. Roembke, Shizuka Nakayama and Herman O. Sintim
DOI: 10.1039/C3MB70304E

Proteomic analysis of exosomal cargo: the challenge of high purity vesicle isolation
Agata Abramowicz, Piotr Widlak and Monika Pietrowska
DOI: 10.1039/C6MB00082G

Why phosphoproteomics is still a challenge
Fiorella A. Solari, Margherita Dell’Aica, Albert Sickmann and René P. Zahedi
DOI: 10.1039/C5MB00024F

Peptide-tags for site-specific protein labelling in vitro and in vivo
Jonathan Lotze, Ulrike Reinhardt, Oliver Seitz and Annette G. Beck-Sickinger
DOI: 10.1039/C6MB00023A

Trials and tribulations of ‘omics data analysis: assessing quality of SIMCA-based multivariate models using examples from pulmonary medicine
Åsa M. Wheelock and Craig E. Wheelock
DOI: 10.1039/C3MB70194H

Mechanism of action-based classification of antibiotics using high-content bacterial image analysis
Kelly C. Peach, Walter M. Bray, Dustin Winslow, Peter F. Linington and Roger G. Linington
DOI: 10.1039/C3MB70027E

Bridging the layers: towards integration of signal transduction, regulation and metabolism into mathematical models
Emanuel Gonçalves, Joachim Bucher, Anke Ryll, Jens Niklas, Klaus Mauch, Steffen Klamt, Miguel Rocha and Julio Saez-Rodriguez
DOI: 10.1039/C3MB25489E

Elucidating the interaction of limonene with bovine serum albumin: a multi-technique approach
Sumit Kumar Chaturvedi, Ejaz Ahmad, Javed Masood Khan, Parvez Alam, Mohd Ishtikhar and Rizwan Hasan Khan
DOI: 10.1039/C4MB00548A

PLS/OPLS models in metabolomics: the impact of permutation of dataset rows on the K-fold cross-validation quality parameters
Mohamed N. Triba, Laurence Le Moyec, Roland Amathieu, Corentine Goossens, Nadia Bouchemal, Pierre Nahon, Douglas N. Rutledge and Philippe Savarin
DOI: 10.1039/C4MB00414K

The transcriptome of Euglena gracilis reveals unexpected metabolic capabilities for carbohydrate and natural product biochemistry
Ellis C. O’Neill, Martin Trick, Lionel Hill, Martin Rejzek, Renata G. Dusi, Chris J. Hamilton, Paul V. Zimba, Bernard Henrissat and Robert A. Field
DOI: 10.1039/C5MB00319A

Evolutionary game theory: cells as players
Sabine Hummert, Katrin Bohl, David Basanta, Andreas Deutsch, Sarah Werner, Günter Theißen, Anja Schroeter and Stefan Schuster
DOI: 10.1039/C3MB70602H

Fatty acid biosynthesis revisited: structure elucidation and metabolic engineering
Joris Beld, D. John Lee and Michael D. Burkart
DOI: 10.1039/C4MB00443D

Exploration of the HIF-1α/p300 interface using peptide and Adhiron phage display technologies
Hannah F. Kyle, Kate F. Wickson, Jonathan Stott, George M. Burslem, Alexander L. Breeze, Christian Tiede, Darren C. Tomlinson, Stuart L. Warriner, Adam Nelson, Andrew J. Wilson and Thomas A. Edwards
DOI: 10.1039/C5MB00284B

Next generation sequencing: implications in personalized medicine and pharmacogenomics
Bahareh Rabbani, Hirofumi Nakaoka, Shahin Akhondzadeh, Mustafa Tekin and Nejat Mahdieh
DOI: 10.1039/C6MB00115G

A quinazoline-based HDAC inhibitor affects gene expression pathways involved in cholesterol biosynthesis and mevalonate in prostate cancer cells
Z. Lin, K. S. Bishop, H. Sutherland, G. Marlow, P. Murray, W. A. Denny and L. R. Ferguson
DOI: 10.1039/C5MB00554J

Systems biology analysis of hepatitis C virus infection reveals the role of copy number increases in regions of chromosome 1q in hepatocellular carcinoma metabolism
Ibrahim E. Elsemman, Adil Mardinoglu, Saeed Shoaie, Taysir H. Soliman and Jens Nielsen
DOI: 10.1039/C5MB00827A

Logical modelling of Drosophila signalling pathways
Abibatou Mbodj, Guillaume Junion, Christine Brun, Eileen E. M. Furlong and Denis Thieffry
DOI: 10.1039/C3MB70187E

Evolutionary game theory: molecules as players
Katrin Bohl, Sabine Hummert, Sarah Werner, David Basanta, Andreas Deutsch, Stefan Schuster, Günter Theißen and Anja Schroeter
DOI: 10.1039/C3MB70601J

Metabolomics in diabetic complications
Laura A. Filla and James L. Edwards
DOI: 10.1039/C6MB00014B

Hierarchical control of coherent gene clusters defines the molecular mechanisms of glioblastoma
Igor F. Tsigelny, Valentina L. Kouznetsova, Pengfei Jiang, Sandeep C. Pingle and Santosh Kesari
DOI: 10.1039/C5MB00007F

Connecting gene expression data from connectivity map and in silico target predictions for small molecule mechanism-of-action analysis
Aakash Chavan Ravindranath, Nolen Perualila-Tan, Adetayo Kasim, Georgios Drakakis, Sonia Liggi, Suzanne C. Brewerton, Daniel Mason, Michael J. Bodkin, David A. Evans, Aditya Bhagwat, Willem Talloen, Hinrich W. H. Göhlmann, QSTAR Consortium, Ziv Shkedy and Andreas Bender
DOI: 10.1039/C4MB00328D

The ring residue proline 8 is crucial for the thermal stability of the lasso peptide caulosegnin II
Julian D. Hegemann, Christopher D. Fage, Shaozhou Zhu, Klaus Harms, Francesco Saverio Di Leva, Ettore Novellino, Luciana Marinelli and Mohamed A. Marahiel
DOI: 10.1039/C6MB00081A

Differential protein profile in sexed bovine semen: shotgun proteomics investigation
Michele De Canio, Alessio Soggiu, Cristian Piras, Luigi Bonizzi, Andrea Galli, Andrea Urbani and Paola Roncada
DOI: 10.1039/C3MB70306A

Comprehensive mapping of O-GlcNAc modification sites using a chemically cleavable tag
Matthew E. Griffin, Elizabeth H. Jensen, Daniel E. Mason, Courtney L. Jenkins, Shannon E. Stone, Eric C. Peters and Linda C. Hsieh-Wilson
DOI: 10.1039/C6MB00138F

A genome-scale metabolic model of Methanococcus maripaludis S2 for CO2 capture and conversion to methane
Nishu Goyal, Hanifah Widiastuti, I. A. Karimi and Zhi Zhou
DOI: 10.1039/C3MB70421A

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