What are your colleagues reading in Molecular BioSystems?

The articles below are some of the most read Molecular BioSystems articles in January, February and March 2016.

Isothermal amplified detection of DNA and RNA
Lei Yan, Jie Zhou, Yue Zheng, Adam S. Gamson, Benjamin T. Roembke, Shizuka Nakayama and Herman O. Sintim
DOI: 10.1039/C3MB70304E, Review Article

Why phosphoproteomics is still a challenge
Fiorella A. Solari, Margherita Dell’Aica, Albert Sickmann and René P. Zahedi
DOI: 10.1039/C5MB00024F, Opinion

Exploration of the HIF-1α/p300 interface using peptide and Adhiron phage display technologies
Hannah F. Kyle, Kate F. Wickson, Jonathan Stott, George M. Burslem, Alexander L. Breeze, Christian Tiede, Darren C. Tomlinson, Stuart L. Warriner, Adam Nelson, Andrew J. Wilson and Thomas A. Edwards
DOI: 10.1039/C5MB00284B, Paper

PLS/OPLS models in metabolomics: the impact of permutation of dataset rows on the K-fold cross-validation quality parameters
Mohamed N. Triba, Laurence Le Moyec, Roland Amathieu, Corentine Goossens, Nadia Bouchemal, Pierre Nahon, Douglas N. Rutledge and Philippe Savarin
DOI: 10.1039/C4MB00414K, Opinion

The PI3K/AKT/mTOR interactive pathway
Tulin Ersahin, Nurcan Tuncbag and Rengul Cetin-Atalay
DOI: 10.1039/C5MB00101C, Paper

Trials and tribulations of ‘omics data analysis: assessing quality of SIMCA-based multivariate models using examples from pulmonary medicine
Åsa M. Wheelock and Craig E. Wheelock
DOI: 10.1039/C3MB70194H, Opinion

The transcriptome of Euglena gracilis reveals unexpected metabolic capabilities for carbohydrate and natural product biochemistry
Ellis C. O’Neill, Martin Trick, Lionel Hill, Martin Rejzek, Renata G. Dusi, Chris J. Hamilton, Paul V. Zimba, Bernard Henrissat and Robert A. Field
DOI: 10.1039/C5MB00319A, Paper

Bridging the layers: towards integration of signal transduction, regulation and metabolism into mathematical models
Emanuel Gonçalves, Joachim Bucher, Anke Ryll, Jens Niklas, Klaus Mauch, Steffen Klamt, Miguel Rocha and Julio Saez-Rodriguez
DOI: 10.1039/C3MB25489E, Review Article

Metabolomic analysis of riboswitch containing E. coli recombinant expression system
Howbeer Muhamadali, Yun Xu, Rosa Morra, Drupad K. Trivedi, Nicholas J. W. Rattray, Neil Dixon and Royston Goodacre
DOI: 10.1039/C5MB00624D, Paper

Mechanism of action-based classification of antibiotics using high-content bacterial image analysis
Kelly C. Peach, Walter M. Bray, Dustin Winslow, Peter F. Linington and Roger G. Linington
DOI: 10.1039/C3MB70027E, Paper

Connecting gene expression data from connectivity map and in silico target predictions for small molecule mechanism-of-action analysis
Aakash Chavan Ravindranath, Nolen Perualila-Tan, Adetayo Kasim, Georgios Drakakis, Sonia Liggi, Suzanne C. Brewerton, Daniel Mason, Michael J. Bodkin, David A. Evans, Aditya Bhagwat, Willem Talloen, Hinrich W. H. Göhlmann, QSTAR Consortium, Ziv Shkedy and Andreas Bender
DOI: 10.1039/C4MB00328D, Paper

Binding mechanisms of 1,4-dihydropyridine derivatives to L-type calcium channel Cav1.2: a molecular modeling study
Lei Xu, Dan Li, Li Tao, Yanling Yang, Youyong Li and Tingjun Hou
DOI: 10.1039/C5MB00781J, Paper

Metabolomics – the complementary field in systems biology: a review on obesity and type 2 diabetes
Mohamad Hafizi Abu Bakar, Mohamad Roji Sarmidi, Kian-Kai Cheng, Abid Ali Khan, Chua Lee Suan, Hasniza Zaman Huri and Harisun Yaakob
DOI: 10.1039/C5MB00158G, Review Article

Discrimination between bacterial species by ratiometric analysis of their carbohydrate binding profile
Lucienne Otten, Elizabeth Fullam and Matthew I. Gibson
DOI: 10.1039/C5MB00720H, Communication

Evolutionary game theory: cells as players
Sabine Hummert, Katrin Bohl, David Basanta, Andreas Deutsch, Sarah Werner, Günter Theißen, Anja Schroeter and Stefan Schuster
DOI: 10.1039/C3MB70602H, Review Article

Evolutionary game theory: molecules as players
Katrin Bohl, Sabine Hummert, Sarah Werner, David Basanta, Andreas Deutsch, Stefan Schuster, Günter Theißen and Anja Schroeter
DOI: 10.1039/C3MB70601J, Review Article

Computational prediction of secretion systems and secretomes of Brucella: identification of novel type IV effectors and their interaction with the host
Jagadesan Sankarasubramanian, Udayakumar S. Vishnu, Vasudevan Dinakaran, Jayavel Sridhar, Paramasamy Gunasekaran and Jeyaprakash Rajendhran
DOI: 10.1039/C5MB00607D, Paper

Discovery of urinary metabolomic biomarkers for early detection of acute kidney injury
A Jin Won, Siwon Kim, Yoon Gyoon Kim, Kyu-Bong Kim, Wahn Soo Choi, Sam Kacew, Kyeong Seok Kim, Jee H. Jung, Byung Mu Lee, Suhkmann Kim and Hyung Sik Kim
DOI: 10.1039/C5MB00492F, Paper

Fatty acid biosynthesis revisited: structure elucidation and metabolic engineering
Joris Beld, D. John Lee and Michael D. Burkart
DOI: 10.1039/C4MB00443D, Review Article

Network-based drug repositioning
Zikai Wu, Yong Wang and Luonan Chen
DOI: 10.1039/C3MB25382A, Review Article

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