Introducing Editorial Board member Michael Washburn
22 Apr 2013
We’re extremely pleased to welcome Michael Washburn as the most recent addition to the Molecular BioSystems Editorial Board and in this blog we like to introduce him and his research vision:
Michael Washburn received his B.A. in chemistry from Grinnell College (Iowa, USA). He then started his graduate studies at Michigan State University and received a Ph.D. in 1998 under the supervision of Prof. William W. Wells. He then conducted post-doctoral training in proteomics in the Department of Molecular Biotechnology at the University of Washington with Dr. John R. Yates, III. In 2000, he moved to San Diego with Dr. Yates and worked at the Torrey Mesa Research Institute as a staff scientist and a senior staff scientist. In 2003, he started his independent career as the Director of Proteomics at the Stowers Institute for Medical Research in Kansas City, MO, USA. His research interests are in quantitative proteomics and systems biology with a particular focus on the analysis of transcriptional regulatory complexes and chromatin remodeling complexes and their protein interaction networks. He has published more than 140 scientific papers to date.
Below, Dr. Washburn shares his view on quantitative proteomics, systems biology, and the research areas he is working in currently:
RESEARCH VISION: Remarkable advances in mass spectrometry and computational analysis over the last decade have resulted in the emergence of powerful proteomics technologies. Furthermore, protein mass spectrometry and proteomics have become more and more of a quantitative science. This has resulted in proteomics analysis having a growing impact on biological and biochemical research. In particular, state of the art and innovative approaches are enabling fascinating studies into protein complexes and protein interaction networks providing information and insights that were not previously possible. We are now in a period where protein interaction networks can be defined, and the technology exists to discern the dynamics of protein interaction networks and protein complexes when stimulated or disrupted. My research group at the Stowers Institute for Medical Research uses innovative and state of the art computational and quantitative proteomics approaches to study protein complexes and protein interaction networks. We also continually develop novel proteomic methods that we then apply to this research. Currently we couple these studies to advanced imaging and genomic techniques to gain deeper insights into the function of novel proteins in complexes and the dynamics of protein interaction networks after stimulation or disruption.