HOT articles: crystal structure of a snake venom component and an opinion on butyrate

As a little Easter present, we at Molecular BioSystems are giving you two HOT articles free to access (following a simple registration for individual users) for the next four weeks!

The first comes from Christian Betzel and co-workers and discusses a myotoxin from the venom of the most venomous snake in Europe! The team studied its 3D structure to gain information about its activity.

Crystal structure of a dimeric Ser49 PLA2-like myotoxic component of the Vipera ammodytes meridionalis venomics reveals determinants of myotoxicity and membrane damaging activity
Dessislava Georgieva, Monika Coronado, Dominik Oberthür, Friedrich Buck, Deyan Duhalov, Raghuvir K. Arni and Christian Betzel
DOI: 10.1039/C2MB05490F

The second article is an opinion piece from Bernard Corfe at the University of Sheffield, discussing the classification of butyrate – an HDAC inhibitor, or a product inhibitor of deacetylation?

Hypothesis: butyrate is not an HDAC inhibitor, but a product inhibitor of deacetylation
Bernard M. Corfe
DOI: 10.1039/C2MB25028D

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