The hot article on the cover of this month’s issue is from Andreas Keller and Christina Backes et al. whose artwork shows their discovery of novel microRNAs in peripheral blood of lung cancer patients. Using high-throughput SOLiD transcriptome sequencing they identified 76 previously unknown miRNAs and 41 novel mature forms of known precursors, which may potentially be used as biomarkers for the disease.
Download the article to read more about this interesting piece of research, which is part of the larger ‘‘Whole Disease miRNome’’ project which aims to improve our understanding of the human miRNome in a wide range of human diseases.
Next-generation sequencing identifies novel microRNAs in peripheral blood of lung cancer patients
Andreas Keller, Christina Backes, Petra Leidinger, Nathalie Kefer, Valesca Boisguerin, Catalin Barbacioru, Britta Vogel, Mark Matzas, Hanno Huwer, Hugo A. Katus, Cord Stähler, Benjamin Meder and Eckart Meese
DOI: 10.1039/C1MB05353A
View the rest of Issue 12, including hot articles on predicting antibody complementarity and how fluorescent labelling agents change binding profiles of glycan-binding proteins.
[...] Backes et al. whose artwork shows their discovery of novel microRNAs in peripheral blood of lung cancer patients. Using high-throughput SOLiD transcriptome sequencing they identified 76 previously unknown [...]
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Great posting thanks for sharing.
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