Archive for the ‘Ongoing Thematic Collections’ Category

Personalised Medicine: Liquid Biopsy

We are delighted to announce our latest Thematic Collection in Lab on a Chip – Personalised Medicine: Liquid Biopsy!

This collection is being lead by Thought Leaders Stefanie Jeffrey and Mehmet Toner.

Stefanie Jeffrey, MD, is the John and Marva Warnock Professor and Chief of Surgical Oncology Research in the Department of Surgery at Stanford University School of Medicine. Her lab focuses on technology development and applications related to liquid biopsy (CTCs, ctDNA, extracellular vesicles), droplet-based microfluidic platforms, and preclinical models for testing new cancer therapies.

Mehmet Toner, PhD, is a member of the faculty at the Center for Engineering in Medicine at Massachusetts General Hospital. Dr. Toner is motivated by multi-disciplinary problems at the interface of engineering and life sciences. In the fields of microfluidics/micro-engineering/cancer he is working on microfluidics in biology and medicine including microfluidic blood processing, developing a microchip to help sort rare cells and integration of living cells and micro-engineered tissue units into micro-devices.

Liquid Biopsy, coined by Pantel and Alix-Panabières in 2010, originally referred to real-time analyses of CTCs in cancer. However, that term has since expanded to encompass the analyses of many other disease-related substances found in blood and other body fluids. Our goal is to highlight the new advances in this growing field with an emphasis on the interface between the technological advancements and high impact applications of liquid biopsy technologies. These would include manuscripts related to components that can be captured or characterized from blood such as circulating tumour cells, circulating nucleic acids and circulating extracellular vesicles.

Interested in submitting to the collection?

If you are interested in submitting to the personalised medicine: liquid biopsy collection, please contact the Lab on a Chip Editorial Office at loc-rsc@rsc.org  and provide a title and abstract of your proposed submission.

Articles will be published as they are accepted and collated into an online Thematic Collection, which will receive extensive promotion. Read the collection so far – http://rsc.li/liquid-biopsy 

Submissions for this collection are open from 1st September 2017 to 30th June 2018

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Droplet-Based Single-Cell Sequencing

We are pleased to announce the latest Thematic Collection in Lab on a ChipDroplet-Based Single-Cell Sequencing!

We are delighted that Lab on a Chip Advisory Board member David A Weitz (Harvard University, USA) is Thought Leader of this collection!

The field of droplet-based single-cell sequencing field has made increasing advances in recent years. Large numbers of studies are underway to collect and explore the new information that is now accessible with single-cell RNA-seq. Improvements to microfluidics are advancing rapidly and extensions to other sequencing methods are also being developed, enabling investigations to probe information beyond mRNA alone. This has rapidly become a burgeoning field, where microfluidic techniques are essential and where droplet-based microfluidics has enabled a major advance.

For more context, please read the editorials “Perspective on droplet-based-single cell sequencing” by David Weitz and “InDrops and Drop-seq technologies for single-cell sequencing” by Allon Klein and Evan Macosko.

The goal of this collection is to highlight the new advances in this growing field, with an emphasis on the interface between the technological advancements and high impact applications of droplet-based single-cell sequencing.

Interested in submitting to the collection?

If you are interested in contributing to the droplet-based single-cell sequencing collection, please get in touch with the Lab on a Chip Editorial Office at loc-rsc@rsc.org and provide a title and abstract of your proposed submission.

Articles will be published as they are accepted and collated into an online Thematic Collection, which will receive extensive promotion.

Submissions for this collection are open from 15th July 2017 to 30th April 2018 

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Organ-, Body- and Disease-on-a-Chip Thematic Collection

We are pleased to announce Lab on a Chip‘s first Thematic Collection in 2017, Organ-, Body- and Disease-on-a-Chip!

We are delighted to announce that Michael Shuler (Cornell University, USA) will be acting as Thought Leader for this collection. His research focuses on “Body-on-a-Chip” devices applied to evaluate different treatments for cancer, such as multi-drug resistant cancer. Read Michael Shuler’s recent Editorial for more information.

An emerging area of interest for drug development over the last 13 years has been constructing human biomimetic systems by combining the techniques of microfabrication and tissue engineering. In this collection, we define an “Organ-on-a-Chip” as a physical microscale model (typically an order of 10−6 to 10−4 of actual size) of a particular human organ.

The questions we aim to address in this collection are whether these emerging technologies will improve both drug development and the regulation of human exposure to chemicals. What technical challenges remain? What will be the most effective way to utilize this emerging technology? Can this technology lead to cost effective, measurable improvements in human health? Our goal is to highlight the new advances in this growing field with an emphasis on the interface between the technological advancements and high impact applications of organ-, body- and disease-on-a-chip technologies.

Interested in submitting to the collection? 

If you are interested in submitting to the series, please get in touch with the Lab on a Chip Editorial Office at loc-rsc@rsc.org and and provide a title and abstract of your proposed submission.

Articles will be published as they are accepted and collated into an online Thematic Collection, which will receive extensive promotion. Read the collection so far – rsc.li/organonachip

Submissions to this collection are open between 1st July 2017 and 31st March 2018

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Emerging Investigator Series for Lab on a Chip

Starting in 2017, Lab on a Chip will be running an Emerging Investigator Series to showcase some of the best work in the field of miniaturisation at the micro- and nano-scale, being conducted by early-career researchers. The Series will ongoing, with articles being published once they are accepted and collated online.

There are many benefits for Emerging Investigators contributing to the series, with articles being featured in an online collection and receiving extensive promotion. This includes a special mention in journal contents alerts and an interview on the journal blog. Published articles will also be made free to access for a limited period. Furthermore, the continuous format is designed to allow more flexibility for contributors to participate in the venture without the restriction of submission deadlines.

We’ve received great feedback from previous Emerging Investigators, including this quote: “Being part of the Emerging Investigators issue was an honor and helpful to my career.  Thanks again for including me” (2012 Emerging Investigator)

Read the articles included in the collection so far at – rsc.li/loc-emerging-investigator

To represent the whole of the Lab on a Chip community, the Series will have two international Series Editors with a broad range of expertise: Editorial Board members, Dino Di Carlo (UCLA, USA), Yoon-Kyoung Cho (UNIST, South Korea) and Piotr Garstecki (IPC PAC, Poland)

 

To be eligible for the new Emerging Investigator Series you will need to have completed your PhD (or equivalent degree) within the last 10 years and have an independent career. If you are interested in contributing to the Series please contact the Editorial Office (loc-rsc@rsc.org) and provide the following information:

  • Your up-to-date CV (no longer than 2 pages), which should include a summary of education and career, a list of relevant publications, any notable awards, honours or professional activities in the field, and a website URL if relevant;
  • A title and abstract of the research article intended to be submitted to the Series, including a tentative submission date. Please note that articles submitted to the journal for the Series will undergo the usual peer review process.

Keep up to date with the latest papers added to this Series on our twitter feed (@LabonaChip) with the hashtags #EmergingInvestigators #LabonaChip

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