Archive for April, 2015

Free access to March’s HOT Articles

These HOT articles published in March 2015 were recommended by our referees and are free* to access for 4 weeks


Electromechanical cell lysis using a portable audio device: enabling challenging sample preparation at the point-of-care

J. R. Buser, A. Wollen, E. K. Heiniger, S. A. Byrnes, P. C. Kauffman, P. D. Ladd and P. Yager
Lab Chip, 2015,15, 1994-1997
DOI: 10.1039/C5LC00080G, Technical Innovation


Implementation of in situ SAXS/WAXS characterization into silicon/glass microreactors

Thomas Beuvier, Elvia Anabela Chavez Panduro, Paweł Kwaśniewski, Samuel Marre, Carole Lecoutre, Yves Garrabos, Cyril Aymonier, Brice Calvignac and Alain Gibaud

Lab Chip, 2015,15, 2002-2008
DOI: 10.1039/C5LC00115C, Paper

Reconfigurable microfluidic systems with reversible seals compatible with 2D and 3D surfaces of arbitrary chemical composition

Abhiteja Konda, Jay M. Taylor, Michael A. Stoller and Stephen A. Morin
Lab Chip, 2015, 15, 2009-2017
DOI: 10.1039/C5LC00026B, Paper

Take a look at our Lab on a Chip 2015 HOT Articles Collection!

*Access is free until 31.05.15 through a publishing personal account. It’s quick, easy and free to register!




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New YouTube videos

Fabrication and Characterization of Optogenetic, Multi-Strip Cardiac Muscles

Direct detection and drug-resistance profiling of bacteremias using inertial microfluidics

Droplet-in-oil array for picoliter-scale analysis based on sequential-inkjet printing

The microenvironment of double emulsions in rectangular microchannels

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Lab on a Chip gives prestigious awards at µTAS 2014

The μTAS conference 2014 was held in October, at the Henry B. Gonzalez Convention Center in San Antonio, Texas.

As in previous years, Harp Minhas, Editor of Lab on a Chip, was in attendance at the conference to announce the prestigious Lab on a Chip awards, which include the Pioneers of Miniaturisation Lectureship (supported by Corning Inc), the Widmer Young Researcher Poster Prize, and the Art in Science Award (co-sponsored by NIST).

New to 2014: The μTAS Video Competition, created in partnership with Dolomite Microfluidics and supported by the CBMS (the Chemical and Biological Microsystems Society) was awarded for the first time at this years conference!

Art in Science Award

The Art in Science Award is given each year “to draw attention to the aesthetic value in scientific illustrations while still conveying scientific merit.” This year’s award was presented to David Castro and research group form the King Abdullah University of Science and Technology (KAUST) in Saudi Arabia. More information on the winning photograph can be found on our competition blog.

Left to Right: Darwin Reyes (NIST) Shilpa Sivashankar (KAUST) Harpal Minhas (LOC) and Albert Folch (University of Washington)

Pioneers of Miniaturisation Lectureship

The Pioneers of Miniaturisation Lectureship recognises early-mid career scientists who demonstrate outstanding achievements and significant contributions to the understanding and advancement of micro- and nano-scale science. This year, the Lectureship was awarded to Sangeeta Bhatia, Massachusetts Institutes of Technology.  Dr Bhatia received a certificate$5000 and gave a short lecture at the conference. You can find out more about Dr Bhatia on our winners blog.

Left to Right: Harpal Minhas (LOC) Sangeeta Bhatia (winner) and Ed Fewkes (Corning Inc.)

Video Competitions

New to 2014 and created in partnership with Dolomite Microfluidics and supported by the CBMS (the Chemical and Biological Microsystems Society) the video competiton was awarded to Tijmen Hageman and colleagues. Prior to the conference, μTAS participants were invited to submit short, scientifically or educationally focused videos. The winning group, a collaboration of researchers from the University of Twente and the Korean Institute of Science and Technology produced a video demonstrating that bacteria can be manipulated by a magnetic field by using magnets to teach bacteria to line dance. The full video can be viewed on our competition blog.

Left to Right: Harpal Minhas (LOC) Tijmen Hageman (winner) and Omar Jina (Dolomite Microfluidics)

Please join us at Lab on a Chip in congratulating all of our prize winners! We look forward to seeing you at μTAS 2015 in Gyeongju, Korea.

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New YouTube videos

A versatile technology for droplet-based microfluidics: thermomechanical actuation

Design and fabrication of magnetically functionalized flexible micropillar arrays for rapid and controllable microfluidic mixing

Active pneumatic control of centrifugal microfluidic flows for lab-on-a-chip applications

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MicroTAS 2014 abstracts are available!

Lab on a Chip presents uTAS Abstracts 2003 to 2014:

The page link below gives the lab on a chip/microfluidics/μTAS communities free access to both current and archived content submitted to the μTAS conferences in the form of extended abstracts. This service will support workers in finding essential references and hence increase knowledge of past work in the field and assist with current and future research.

Abstracts are available through the following link: http://rsc.li/1eYWXQs

This archive includes abstracts presented at uTAS meetings from 2003 to present and essentially provides easy web access to the abstract discs supplied at the uTAS meetings.

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Textile Weaving: a new cheaper alternative to electrochemical sensors

Electrochemical sensors are widely used as analytical tools. They are disposable, cheap to make, and small – making them ideal for many applications.

The current method for commercial electrochemical sensors uses screen printing onto plastic or ceramic surfaces to generate the circuit elements, which requires specialised fabrication equipment. This screen printing method also leads to wastage of electrode inks and reagents. One way of avoiding these issues is using paper microfluidics – Professor George Whitesides is a well-known name in this field.

Dendukuri and coworkers, from Achira Labs, Bangalore, have come at this problem from a different angle. They have developed an alternative approach using textile weaving. Instead of screen printing, they coat their yarn with the required reagents in a way that results in no wastage, as shown in the photo. They use silk as their material which is biodegradable, unlike the plastics usually used. It is also easily processed – initially silk is hydrophobic but it can be made hydrophobic by degumming. This can be achieved by simply boiling the yarn.

To make the sensors, electrode yarns are prepared by coating in conductive inks and reagents, and then woven into the fabric. Large numbers of sensors can be woven as patches on the fabric, which are then stuck onto an adhesive backing and laminated, leaving a window for application of the sample and for contact with a reader.To demonstrate this effectiveness of this new method, the authors developed glucose and haemoglobin sensors. The glucose sensors were found to have a clinically acceptable performance, according to FDA criteria, while the haemoglobin sensors were able to detect physiologically relevant concentrations. Multiplexed sensors capable of detecting more than one analyte were easily prepared by adding an additional electrode.

One of the most pleasing aspects of this new method, is its potential in the developing world, where weaving is still widely used. In addition, the cost of manufacture was calculated as less than 20 USD per 1000 sensors and this could even lower on scale up.

To download the full article for free* click the link below:

Woven electrochemical fabric-based test sensors (WEFTS): a new class of multiplexed electrochemical sensors
Tripurari Choudhary, G. P. Rajamanickam and Dhananjaya Dendukuri
DOI: 10.1039/C5LC00041F

*Access is free until 30.04.2015 through a registered RSC Personal Publishing Account

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