Spectral interferences using Inorganic Mass Spectrometry

Analysis of Human urine after administration of Gd-based MRI contrast agents

Administration of Gd-based MRI contrast agents causes major spectral interferences during analysis of selenium (Se) and platinum (Pt) in urine.

The finding was reported in a new study led by Amy Steuerwald who carried out an epidemiological study on 619 urine specimens to determine Se and Pt using quadruple-based inductively coupled plasma mass spectrometry (Q-ICP-MS). Both Se and Pt were several orders of magnitude greater than the upper limit of the population reference ranges.

To read the full article, please access the link below. This paper will be free to read until April 12th.

Trace element analysis of human urine collected after administration of Gd-based MRI contrast agents: characterizing spectral interferences using inorganic mass spectrometry
Amy J. Steuerwald ,  Patrick J. Parsons ,  John G. Arnason ,  Zhen Chen ,  C. Matthew Peterson and Germaine M. Buck Louis
J. Anal. At. Spectrom., 2013, Advance Article
DOI: 10.1039/C3JA30331D

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