In a step towards determining impurities in pharmaceutical compounds, Jiří Dědina from the Institute of Analytical Chemistry of the ASCR, Czech Republic, and colleagues from the Czech Republic and Brazil have used hydride generation-cryotrapping-gas chromatography-atomic absorption spectrometry for arsenic speciation analysis in an injectable drug. In this case they have tested N-methylglucamine antimonate, a drug used in the treatment of Leishmaniasis, a disease caused by protozoan parasites transmitted through the bite of sandflies. Read more about this important research by clicking on the link below, the paper will be free to read for 2 weeks.
Selective generation of substituted arsines-cryotrapping-atomic absorption spectrometry for arsenic speciation analysis in N-methylglucamine antimonate
Diogo P. Moraes, Milan Svoboda, Tomáš Matoušek, Erico M. M. Flores and Jiří Dědina
J. Anal. At. Spectrom., 2012, Advance Article