Archive for the ‘Top Ten’ Category

Top ten most accessed IB articles in Q1 2014

This month sees the following articles in Integrative Biology that are in the top ten most accessed January – March:-

Mesoporous silica nanoparticles: A multifunctional nano therapeutic system
Wilson X. Mai and Huan Meng   
Integr. Biol., 2013,5, 19-28  
DOI: 10.1039/C2IB20137B  
  
Single-molecule imaging in vivo: the dancing building blocks of the cell 
Miguel Coelho, Nicola Maghelli and Iva M. Tolić-Nørrelykke   
Integr. Biol., 2013,5, 748-758 
DOI: 10.1039/C3IB40018B
  
Nanoparticles and their applications in cell and molecular biology 
Edina C. Wang and Andrew Z. Wang 
Integr. Biol., 2014,6, 9-26 
DOI: 10.1039/C3IB40165K  
  
Unraveling intestinal stem cell behavior with models of crypt dynamics 
Alexis J. Carulli, Linda C. Samuelson and Santiago Schnell    
Integr. Biol., 2014,6, 243-257 
DOI: 10.1039/C3IB40163D 
 
DNA assembly for synthetic biology: from parts to pathways and beyond 
Tom Ellis, Tom Adie and Geoff S. Baldwin  
Integr. Biol., 2011,3, 109-118 
DOI: 10.1039/C0IB00070A  
   
Mechanisms of tumor cell extravasation in an in vitro microvascular network platform 
Michelle B. Chen, Jordan A. Whisler, Jessie S. Jeon and Roger D. Kamm    
Integr. Biol., 2013,5, 1262-1271
DOI: 10.1039/C3IB40149A, Paper 
  
Biological applications of microfluidic gradient devices 
Sudong Kim, Hyung Joon Kim and Noo Li Jeon    
Integr. Biol., 2010,2, 584-603
DOI: 10.1039/C0IB00055H  
 
Directed cell migration in multi-cue environments 
Laura Lara Rodriguez and Ian C. Schneider    
Integr. Biol., 2013,5, 1306-1323
DOI: 10.1039/C3IB40137E  
 
Advances in magnetic tweezers for single molecule and cell biophysics 
Devrim Kilinc and Gil U. Lee    
Integr. Biol., 2014,6, 27-34
DOI: 10.1039/C3IB40185E  

Topographical control of multiple cell adhesion molecules for traction force microscopy 
Samuel R. Polio, Harikrishnan Parameswaran, Elizabeth P. Canović, Carolynn M. Gaut, Diana Aksyonova, Dimitrije Stamenović and Michael L. Smith    
Integr. Biol., 2014,6, 357-365
DOI: 10.1039/C3IB40127H

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Top ten most accessed IB articles in Q4 2013

This month sees the following articles in Integrative Biology that are in the top ten most accessed October – December:-

Single-molecule imaging in vivo: the dancing building blocks of the cell 
Miguel Coelho, Nicola Maghelli and Iva M. Tolić-Nørrelykke   
Integr. Biol., 2013,5, 748-758
DOI: 10.1039/C3IB40018B   

Transition to invasion in breast cancer: a microfluidic in vitro model enables examination of spatial and temporal effects 
Kyung Eun Sung, Ning Yang, Carolyn Pehlke, Patricia J. Keely, Kevin W. Eliceiri, Andreas Friedl and David J. Beebe    
Integr. Biol., 2011,3, 439-450 
DOI: 10.1039/C0IB00063A 
   

Biological applications of microfluidic gradient devices 
Sudong Kim, Hyung Joon Kim and Noo Li Jeon   
Integr. Biol., 2010,2, 584-603
DOI: 10.1039/C0IB00055H  
   

Mechanisms of tumor cell extravasation in an in vitro microvascular network platform 
Michelle B. Chen, Jordan A. Whisler, Jessie S. Jeon and Roger D. Kamm    
Integr. Biol., 2013,5, 1262-1271
DOI: 10.1039/C3IB40149A 
   

Directed cell migration in multi-cue environments 
Laura Lara Rodriguez and Ian C. Schneider  
Integr. Biol., 2013,5, 1306-1323
DOI: 10.1039/C3IB40137E  
   

DNA assembly for synthetic biology: from parts to pathways and beyond 
Tom Ellis, Tom Adie and Geoff S. Baldwin    
Integr. Biol., 2011,3, 109-118 
DOI: 10.1039/C0IB00070A  
   

Mesoporous silica nanoparticles: A multifunctional nano therapeutic system 
Wilson X. Mai and Huan Meng    
Integr. Biol., 2013,5, 19-28 
DOI: 10.1039/C2IB20137B 
    

A co-culture device with a tunable stiffness to understand combinatorial cell–cell and cell–matrix interactions 
Nikhil Rao, Gregory N. Grover, Ludovic G. Vincent, Samantha C. Evans, Yu Suk Choi, Katrina H. Spencer, Elliot E. Hui, Adam J. Engler and Karen L. Christman    
Integr. Biol., 2013,5, 1344-1354 
DOI: 10.1039/C3IB40078F  
  

Nanoparticles and their applications in cell and molecular biology 
Edina C. Wang and Andrew Z. Wang    
Integr. Biol., 2014,6, 9-26 
DOI: 10.1039/C3IB40165K  
   

Gut-on-a-Chip microenvironment induces human intestinal cells to undergo villus differentiation 
Hyun Jung Kim and Donald E. Ingber    
Integr. Biol., 2013,5, 1130-1140 
DOI: 10.1039/C3IB40126J

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Top ten most accessed IB articles in Q3 2013

This month sees the following articles in Integrative Biology that are in the top ten most accessed July – September:-

Mechanisms of tumor cell extravasation in an in vitro microvascular network platform
Michelle B. Chen, Jordan A. Whisler, Jessie S. Jeon and Roger D. Kamm
Integr. Biol., 2013,5, 1262-1271
DOI: 10.1039/c3ib40149a

Cells, tissues, and organs on chips: challenges and opportunities for the cancer tumor microenvironment
Edmond W. K. Young
Integr. Biol., 2013,5, 1096-1109
DOI: 10.1039/C3IB40076J

Biological applications of microfluidic gradient devices
Sudong Kim, Hyung Joon Kim and Noo Li Jeon
Integr. Biol., 2010,2, 584-603
DOI: 10.1039/C0IB00055H

Gut-on-a-Chip microenvironment induces human intestinal cells to undergo villus differentiation
Hyun Jung Kim and Donald E. Ingber
Integr. Biol., 2013,5, 1130-1140
DOI: 10.1039/C3IB40126J

Cells, tissues, and organs on chips: challenges and opportunities for the cancer tumor microenvironment
Edmond W. K. Young
Integr. Biol., 2013,5, 1096-1109
DOI: 10.1039/C3IB40076J

Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment
Kyung-Jin Jang, Ali Poyan Mehr, Geraldine A. Hamilton, Lori A. McPartlin, Seyoon Chung, Kahp-Yang Suh and Donald E. Ingber
Integr. Biol., 2013,5, 1119-1129
DOI: 10.1039/C3IB40049B

Guidance of collective cell migration by substrate geometry
Kevin Doxzen, Sri Ram Krishna Vedula, Man Chun Leong, Hiroaki Hirata, Nir S. Gov, Alexandre J. Kabla, Benoit Ladoux and Chwee Teck Lim
Integr. Biol., 2013,5, 1026-1035
DOI: 10.1039/C3IB40054A

Single-molecule imaging in vivo: the dancing building blocks of the cell
Miguel Coelho, Nicola Maghelli and Iva M. Tolić-Nørrelykke
Integr. Biol., 2013,5, 748-758
DOI: 10.1039/C3IB40018B

DNA assembly for synthetic biology: from parts to pathways and beyond
Tom Ellis, Tom Adie and Geoff S. Baldwin
Integr. Biol., 2011,3, 109-118
DOI: 10.1039/C0IB00070A

Mesoporous silica nanoparticles: A multifunctional nano therapeutic system
Wilson X. Mai and Huan Meng
Integr. Biol., 2013,5, 19-28
DOI: 10.1039/C2IB20137B

Microfluidic sample preparation: cell lysis and nucleic acid purification
Jungkyu Kim, Michael Johnson, Parker Hill and Bruce K. Gale
Integr. Biol., 2009,1, 574-586
DOI: 10.1039/B905844C

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Top ten most accessed IB articles in Q2 2013

This month sees the following articles in Integrative Biology that are in the top ten most accessed April – July:-

Single-molecule imaging in vivo: the dancing building blocks of the cell
Miguel Coelho, Nicola Maghelli and Iva M. Tolić-Nørrelykke
Integr. Biol., 2013,5, 748-758
DOI: 10.1039/C3IB40018B

Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment
Kyung-Jin Jang, Ali Poyan Mehr, Geraldine A. Hamilton, Lori A. McPartlin, Seyoon Chung, Kahp-Yang Suh and Donald E. Ingber
Integr. Biol., 2013,5, 1119-1129
DOI: 10.1039/C3IB40049B

DNA assembly for synthetic biology: from parts to pathways and beyond
Tom Ellis, Tom Adie and Geoff S. Baldwin
Integr. Biol., 2011,3, 109-118
DOI: 10.1039/C0IB00070A

Mesoporous silica nanoparticles: A multifunctional nano therapeutic system
Wilson X. Mai and Huan Meng
Integr. Biol., 2013,5, 19-28
DOI: 10.1039/C2IB20137B

Expansion of breast cancer stem cells with fibrous scaffolds
Sheng Feng, Xinrui Duan, Pang-Kuo Lo, Shou Liu, Xinfeng Liu, Hexin Chen and Qian Wang
Integr. Biol., 2013,5, 768-777
DOI: 10.1039/C3IB20255K

Biological applications of microfluidic gradient devices
Sudong Kim, Hyung Joon Kim and Noo Li Jeon
Integr. Biol., 2010,2, 584-603
DOI: 10.1039/C0IB00055H

Biological characterizations of [Gd@C82(OH)22] n nanoparticles as fullerene derivatives for cancer therapy
Jie Meng, Xingjie Liang, Xiaoyuan Chen and Yuliang Zhao
Integr. Biol., 2013,5, 43-47
DOI: 10.1039/C2IB20145C

Development of siRNA-probes for studying intracellular trafficking of siRNA nanoparticles
Christopher A. Alabi, Gaurav Sahay, Robert Langer and Daniel G. Anderson
Integr. Biol., 2013,5, 224-230
DOI: 10.1039/C2IB20155K

A high-throughput nanoimmunoassay chip applied to large-scale vaccine adjuvant screening
Jose L. Garcia-Cordero, Chiara Nembrini, Armando Stano, Jeffrey A. Hubbell and Sebastian J. Maerkl
Integr. Biol., 2013,5, 650-658
DOI: 10.1039/C3IB20263A

Critical review: cellular mechanobiology and amoeboid migration
Jochen Guck, Franziska Lautenschläger, Stephan Paschke and Michael Beil
Integr. Biol., 2010,2, 575-583
DOI: 10.1039/C0IB00050G

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Top ten most accessed IB articles in January 2013

This month sees the following articles in Integrative Biology that are in the top ten most accessed:-

Mesoporous silica nanoparticles: A multifunctional nano therapeutic system 
Wilson X. Mai and Huan Meng  
Integr. Biol., 2013, 5, 19-28 
DOI: 10.1039/C2IB20137B   

Screening therapeutic EMT blocking agents in a three-dimensional microenvironment 
Amir R. Aref, Ruby Yun-Ju Huang, Weimiao Yu, Kian-Ngiap Chua, Wei Sun, Ting-Yuan Tu, Jing Bai, Wen-Jing Sim, Ioannis K. Zervantonakis, Jean Paul Thiery and Roger D. Kamm  
Integr. Biol., 2013, 5, 381-389 
DOI: 10.1039/C2IB20209C 

DNA assembly for synthetic biology: from parts to pathways and beyond 
Tom Ellis, Tom Adie and Geoff S. Baldwin  
Integr. Biol., 2011, 3, 109-118 
DOI: 10.1039/C0IB00070A 

Stimulus-responsive nanopreparations for tumor targeting 
Lin Zhu and Vladimir P. Torchilin  
Integr. Biol., 2013, 5, 96-107 
DOI: 10.1039/C2IB20135F  

Responsive culture platform to examine the influence of microenvironmental geometry on cell function in 3D 
April M. Kloxin, Katherine J. R. Lewis, Cole A. DeForest, Gregory Seedorf, Mark W. Tibbitt, Vivek Balasubramaniam and Kristi S. Anseth  
Integr. Biol., 2012, 4, 1540-1549 
DOI: 10.1039/C2IB20212C  
 
Enabling screening in 3D microenvironments: probing matrix and stromal effects on the morphology and proliferation of T47D breast carcinoma cells 
Sara I. Montanez-Sauri, Kyung Eun Sung, Erwin Berthier and David J. Beebe  
Integr. Biol., 2013, 5, 631-640 
DOI: 10.1039/C3IB20225A  

In situ click chemistry: from small molecule discovery to synthetic antibodies 
Steven W. Millward, Heather D. Agnew, Bert Lai, Su Seong Lee, Jaehong Lim, Arundhati Nag, Suresh Pitram, Rosemary Rohde and James R. Heath 
Integr. Biol., 2013, 5, 87-95 
DOI: 10.1039/C2IB20110K  

Toward personalized cancer nanomedicine – past, present, and future 
Alexander H. Stegh 
Integr. Biol., 2013, 5, 48-65 
DOI: 10.1039/C2IB20104F  
 
Clinically-translated silica nanoparticles as dual-modality cancer-targeted probes for image-guided surgery and interventions 
Michelle S. Bradbury, Evan Phillips, Pablo H. Montero, Sarah M. Cheal, Hilda Stambuk, Jeremy C. Durack, Constantinos T. Sofocleous, Richard J. C. Meester, Ulrich Wiesner and Snehal Patel 
Integr. Biol., 2013, 5, 74-86 
DOI: 10.1039/C2IB20174G  

Mechanobiology: a new frontier for human pluripotent stem cells 
Yubing Sun and Jianping Fu  
Integr. Biol., 2013, 5, 450-457 
DOI: 10.1039/C2IB20256E  

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Top ten most accessed articles in August

The following articles were the top ten most accessed in Integrative Biology for August:

Nanopatterned cardiac cell patches promote stem cell niche formation and myocardial regeneration
Deok-Ho Kim, Kshitiz, Rachel R. Smith, Pilnam Kim, Eun Hyun Ahn, Hong-Nam Kim, Eduardo Marbán, Kahp-Yang Suh and Andre Levchenko
Integr. Biol., 2012, 4, 1019-1033
DOI: 10.1039/C2IB20067H

Control of stem cell fate and function by engineering physical microenvironments
Kshitiz, JinSeok Park, Peter Kim, Wilda Helen, Adam J. Engler, Andre Levchenko and Deok-Ho Kim
Integr. Biol., 2012, 4, 1008-1018
DOI: 10.1039/C2IB20080E

Biological applications of microfluidic gradient devices
Sudong Kim, Hyung Joon Kim and Noo Li Jeon
Integr. Biol., 2010, 2, 584-603
DOI: 10.1039/C0IB00055H

Common pitfalls in nanotechnology: lessons learned from NCI’s Nanotechnology Characterization Laboratory
Rachael M. Crist, Jennifer Hall Grossman, Anil K. Patri, Stephan T. Stern, Marina A. Dobrovolskaia, Pavan P. Adiseshaiah, Jeffrey D. Clogston and Scott E. McNeil
Integr. Biol., 2012, Advance Article
DOI: 10.1039/C2IB20117H

Cancer develops, progresses and responds to therapies through restricted perturbation of the protein–protein interaction network
Jordi Serra-Musach, Helena Aguilar, Francesco Iorio, Francesc Comellas, Antoni Berenguer, Joan Brunet, Julio Saez-Rodriguez and Miguel Angel Pujana
Integr. Biol., 2012, 4, 1038-1048
DOI: 10.1039/C2IB20052J

The evolution of chemotaxis assays from static models to physiologically relevant platforms
Stephanie Toetsch, Peter Olwell, Adriele Prina-Mello and Yuri Volkov
Integr. Biol., 2009, 1, 170-181
DOI: 10.1039/B814567A

DNA assembly for synthetic biology: from parts to pathways and beyond
Tom Ellis, Tom Adie and Geoff S. Baldwin
Integr. Biol., 2011, 3, 109-118
DOI: 10.1039/C0IB00070A

Soft microenvironments promote the early neurogenic differentiation but not self-renewal of human pluripotent stem cells
Albert J. Keung, Prashanth Asuri, Sanjay Kumar and David V. Schaffer
Integr. Biol., 2012, 4, 1049-1058
DOI: 10.1039/C2IB20083J

Toward personalized cancer nanomedicine – past, present, and future
Alexander H. Stegh
Integr. Biol., 2012, Advance Article
DOI: 10.1039/C2IB20104F

Microfluidic sample preparation: cell lysis and nucleic acid purification
Jungkyu Kim, Michael Johnson, Parker Hill and Bruce K. Gale
Integr. Biol., 2009, 1, 574-586
DOI: 10.1039/B905844C

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Top ten most accessed articles in July 2012

This month sees the following articles in Integrative Biology that are in the top ten most accessed:

Single-cell level co-culture platform for intercellular communication
Soongweon Hong, Qiong Pan and Luke P. Lee  
Integr. Biol., 2012, 4, 374-380
DOI: 10.1039/C2IB00166G  

Biological applications of microfluidic gradient devices
Sudong Kim, Hyung Joon Kim and Noo Li Jeon 
Integr. Biol., 2010, 2, 584-603
DOI: 10.1039/C0IB00055H  

Bio-inspired materials for parsing matrix physicochemical control of cell migration: A Review 
Hyung-Do Kim and Shelly R. Peyton  
Integr. Biol., 2012, 4, 37-52
DOI: 10.1039/C1IB00069A  

Microfluidic sample preparation: cell lysis and nucleic acid purification 
Jungkyu Kim, Michael Johnson, Parker Hill and Bruce K. Gale  
Integr. Biol., 2009, 1, 574-586
DOI: 10.1039/B905844C 

Functional characterization and axonal transport of quantum dot labeled BDNF 
Wenjun Xie, Kai Zhang and Bianxiao Cui 
Integr. Biol., 2012, 4, 953-960
DOI: 10.1039/C2IB20062G  

Nanomedicine boosts neurogenesis: new strategies for brain repair 
Tiago Santos, João Maia, Fabienne Agasse, Sara Xapelli, Lino Ferreira and Liliana Bernardino  
Integr. Biol., 2012, 4, 973-981
DOI: 10.1039/C2IB20129A 

DNA assembly for synthetic biology: from parts to pathways and beyond 
Tom Ellis, Tom Adie and Geoff S. Baldwin  
Integr. Biol., 2011, 3, 109-118
DOI: 10.1039/C0IB00070A  

Control of stem cell fate and function by engineering physical microenvironments 
Kshitiz, JinSeok Park, Peter Kim, Wilda Helen, Adam J. Engler, Andre Levchenko and Deok-Ho Kim  
Integr. Biol., 2012, 4, 1008-1018
DOI: 10.1039/C2IB20080E  

Microfluidics for bacterial chemotaxis 
Tanvir Ahmed, Thomas S. Shimizu and Roman Stocker  
Integr. Biol., 2010, 2, 604-629
DOI: 10.1039/C0IB00049C  

Fluid flow stress induced contraction and re-spread of mesenchymal stem cells: a microfluidic study 
Wenfu Zheng, Yunyan Xie, Wei Zhang, Dong Wang, Wanshun Ma, Zhuo Wang and Xingyu Jiang  
Integr. Biol., 2012, 4, 1102-1111
DOI: 10.1039/C2IB20094E  

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Top ten most accessed articles in June

This month sees the following articles in Integrative Biology that are in the top ten most accessed:

Regulation of morphogenesis and neural differentiation of human mesenchymal stem cells using carbon nanotube sheets
Jeong Ah Kim, Eui Yun Jang, Tae June Kang, Sungjun Yoon, Raquel Ovalle-Robles, Won Jong Rhee, Taewoo Kim, Ray H. Baughman, Yong Hyup Kim and Tai Hyun Park
Integr. Biol., 2012, 4, 587-594
DOI: 10.1039/C2IB20017A

In vivo fluorescence imaging of atherosclerotic plaques with activatable cell-penetrating peptides targeting thrombin activity
Emilia S. Olson, Michael A. Whitney, Beth Friedman, Todd A. Aguilera, Jessica L. Crisp, Fred M. Baik, Tao Jiang, Stephen M. Baird, Sotirios Tsimikas, Roger Y. Tsien and Quyen T. Nguyen
Integr. Biol., 2012, 4, 595-605
DOI: 10.1039/C2IB00161F

DNA assembly for synthetic biology: from parts to pathways and beyond
Tom Ellis, Tom Adie and Geoff S. Baldwin
Integr. Biol., 2011, 3, 109-118
DOI: 10.1039/C0IB00070A

Breast tumour initiating cell fate is regulated by microenvironmental cues from an extracellular matrix
Sharmistha Saha, Pang-Kuo Lo, Xinrui Duan, Hexin Chen and Qian Wang
Integr. Biol., 2012, 4, 897-904
DOI: 10.1039/C2IB20034A

Biological applications of microfluidic gradient devices
Sudong Kim, Hyung Joon Kim and Noo Li Jeon
Integr. Biol., 2010, 2, 584-603
DOI: 10.1039/C0IB00055H

Single-cell level co-culture platform for intercellular communication
Soongweon Hong, Qiong Pan and Luke P. Lee
Integr. Biol., 2012, 4, 374-380
DOI: 10.1039/C2IB00166G

The evolution of chemotaxis assays from static models to physiologically relevant platforms
Stephanie Toetsch, Peter Olwell, Adriele Prina-Mello and Yuri Volkov
Integr. Biol., 2009, 1, 170-181
DOI: 10.1039/B814567A

Microfluidic sample preparation: cell lysis and nucleic acid purification
Jungkyu Kim, Michael Johnson, Parker Hill and Bruce K. Gale
Integr. Biol., 2009, 1, 574-586
DOI: 10.1039/B905844C

Mechanism of a flow-gated angiogenesis switch: early signaling events at cell–matrix and cell–cell junctions
Vernella Vickerman and Roger D. Kamm
Integr. Biol., 2012, 4, 863-874
DOI: 10.1039/C2IB00184E

Homing peptides as targeted delivery vehicles
Pirjo Laakkonen and Kirsi Vuorinen
Integr. Biol., 2010, 2, 326-337
DOI: 10.1039/C0IB00013B

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Top ten most accessed articles in May

This month sees the following articles in Integrative Biology that are in the top ten most accessed:

Organs-on-chips: breaking the in vitro impasse
Andries D. van der Meer and Albert van den Berg
Integr. Biol., 2012, 4, 461-470
DOI: 10.1039/C2IB00176D

RhoA-induced cytoskeletal tension controls adaptive cellular remodeling to mechanical signaling
Soon-Mi Lim, Jerome P. Trzeciakowski, Harini Sreenivasappa, Lawrence J. Dangott and Andreea Trache
Integr. Biol., 2012, 4, 615-627
DOI: 10.1039/C2IB20008B

DNA assembly for synthetic biology: from parts to pathways and beyond
Tom Ellis, Tom Adie and Geoff S. Baldwin
Integr. Biol., 2011, 3, 109-118
DOI: 10.1039/C0IB00070A

Single-cell level co-culture platform for intercellular communication
Soongweon Hong, Qiong Pan and Luke P. Lee
Integr. Biol., 2012, 4, 374-380
DOI: 10.1039/C2IB00166G

In vivo fluorescence imaging of atherosclerotic plaques with activatable cell-penetrating peptides targeting thrombin activity
Emilia S. Olson, Michael A. Whitney, Beth Friedman, Todd A. Aguilera, Jessica L. Crisp, Fred M. Baik, Tao Jiang, Stephen M. Baird, Sotirios Tsimikas, Roger Y. Tsien and Quyen T. Nguyen
Integr. Biol., 2012, 4, 595-605
DOI: 10.1039/C2IB00161F

Biological applications of microfluidic gradient devices
Sudong Kim, Hyung Joon Kim and Noo Li Jeon
Integr. Biol., 2010, 2, 584-603
DOI: 10.1039/C0IB00055H

Systematic analysis of embryonic stem cell differentiation in hydrodynamic environments with controlled embryoid body size
Melissa A. Kinney, Rabbia Saeed and Todd C. McDevitt
Integr. Biol., 2012, 4, 641-650
DOI: 10.1039/C2IB00165A

Experiment and mathematical modeling of gene expression dynamics in a cell-free system
Tobias Stögbauer, Lukas Windhager, Ralf Zimmer and Joachim O. Rädler
Integr. Biol., 2012, 4, 494-501
DOI: 10.1039/C2IB00102K

A single cell bioengineering approach to elucidate mechanisms of adult stem cell self-renewal
Penney M. Gilbert, Stephane Corbel, Regis Doyonnas, Karen Havenstrite, Klas E. G. Magnusson and Helen M. Blau
Integr. Biol., 2012, 4, 360-367
DOI: 10.1039/C2IB00148A

Actin filaments play a primary role for structural integrity and viscoelastic response in cells
Alperen N. Ketene, Paul C. Roberts, Amanda A. Shea, Eva M. Schmelz and Masoud Agah
Integr. Biol., 2012, 4, 540-549
DOI: 10.1039/C2IB00168C

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Top ten most accessed articles in April

This month sees the following articles in Integrative Biology that are in the top ten most accessed:

Single-cell level co-culture platform for intercellular communication
Soongweon Hong, Qiong Pan and Luke P. Lee
Integr. Biol., 2012, 4, 374-380
DOI: 10.1039/C2IB00166G

Experiment and mathematical modeling of gene expression dynamics in a cell-free system
Tobias Stögbauer, Lukas Windhager, Ralf Zimmer and Joachim O. Rädler
Integr. Biol., 2012, 4, 494-501
DOI: 10.1039/C2IB00102K

DNA assembly for synthetic biology: from parts to pathways and beyond
Tom Ellis, Tom Adie and Geoff S. Baldwin
Integr. Biol., 2011, 3, 109-118
DOI: 10.1039/C0IB00070A

Organs-on-chips: breaking the in vitro impasse
Andries D. van der Meer and Albert van den Berg
Integr. Biol., 2010, Advance Article
DOI: 10.1039/C2IB00176D

A single cell bioengineering approach to elucidate mechanisms of adult stem cell self-renewal
Penney M. Gilbert, Stephane Corbel, Regis Doyonnas, Karen Havenstrite, Klas E. G. Magnusson and Helen M. Blau
Integr. Biol., 2012, 4, 360-367
DOI: 10.1039/C2IB00148A

From single cells to biology
Mina J. Bissell, Cyrus M. Ghajar and Luke P. Lee
Integr. Biol., 2012, 4, 357-359
DOI: 10.1039/C2IB90010F

Biological applications of microfluidic gradient devices
Sudong Kim, Hyung Joon Kim and Noo Li Jeon
Integr. Biol., 2010, 2, 584-603
DOI: 10.1039/C0IB00055H

Quantitative and dynamic assay of single cell chemotaxis
Sung Sik Lee,  Peter Horvath,  Serge Pelet,  Björn Hegemann,  Luke P. Lee and Matthias Peter
Integr. Biol., 2012, 4, 381-390
DOI: 10.1039/C2IB00144F

Bio-inspired materials for parsing matrix physicochemical control of cell migration: A Review
Hyung-Do Kim and Shelly R. Peyton
Integr. Biol., 2012, 4, 37-52
DOI: 10.1039/C1IB00069A

Migration dynamics of breast cancer cells in a tunable 3D interstitial flow chamber
Ulrike Haessler, Jeremy C. M. Teo, Didier Foretay, Philippe Renaud and Melody A. Swartz
Integr. Biol., 2012, Advance Article
DOI: 10.1039/C1IB00128K

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