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Single Cell Science and Technology Microfluidics Symposium 2017

Single Cell Science and Technology
Microfluidics Symposium 2017
May 3, 2017, 11:00 a.m. to 5 p.m.
NCRC Bldg. 10 Auditorium, Bldg. 18 – Dining Hall


Also including presentations by University of Michigan Faculty and Students

Call for Abstracts for Poster Session
To be considered for podium presentation, submit by March 31, 2017
Deadline for all abstracts: April 18, 2017
Poster Information/Submission: metzlerp@umich.edu
Poster prizes sponsored by MCIRCC and RSC Publishing

 

For more information, see their flyer and click here to register

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Zinc spark shows sperm the chequered flag

Researchers shed light on new explanation for how mammalian zygotes safeguard their survival

Bursts of zinc released within minutes of fertilisation stop reproductive chaos by preventing multiple sperm from binding to eggs, new research shows. 

A team led by Teresa Woodruff and Thomas O’Halloran at Northwestern University, US, first witnessed the almost immediate efflux of billions of zinc ions upon mammalian egg fertilisation with x-ray fluorescence microscopy in 2010. These zinc sparks look like supernovae, according to O’Halloran. Diffusing away from the cell’s membrane, the zinc ions encounter the zona pellucida, a glycoprotein matrix surrounding the egg. Now the team has revealed that zinc retained by the zona pellucida induces changes that harden its protein structure within 30–60 minutes of fertilisation, making it more resistant to sperm binding.

Read the full article in Chemistry World.


Zinc sparks induce physiochemical changes in the egg zona pellucida that prevent polyspermy

Emily L. Que, Francesca E. Duncan, Amanda R. Bayer, Steven J. Philips, Eric W. Roth, Reiner Bleher, Sophie C. Gleber, Stefan Vogt, Teresa K. Woodruff and Thomas V. O’Halloran

DOI: 10.1039/c6ib00212a

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Biophysical Society: 61st Annual Meeting

The Biophysical Societies 61st Annual Meeting will be held in New Orleans, Louisiana on 11th to 15th February this year. The conference aims to bring together scientists working “at the interface of the life, physical, and computational sciences”. The 5 day event includes “Saturday Subgroup” symposia, allowing attendees to meet within their specific scientific communities.

We are delighted to announce that Integrative Biology will be sponsoring the Mechanobiology symposium! The session is chaired by Ewa Paluch from the University of London and includes talks by Ana J. García-Sáez (University of Tuebingen), Nikita Fakhri (MIT) and Kevin J Chalut (University of Cambridge). For more details on the program and to register to attend, visit the conference webpage.

Integrative Biology publishes innovative work in which new biological insights have been achieved through the use of developing technologies from the nano to macroscale. It is a home for all areas of mechanobiology, from molecular to organ scale, experimental, theoretical and computational analysis. If you are working in this area, then we would be delighted if you would consider publishing your work with us!

Interested in Mechanobiology, but can’t make this meeting? Why not read Integrative Biology’s recent themed issue on topic here –  http://rsc.li/1jsLAGD 

 

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