Issue 5 now online! 3D cell culture, systems medicine, single-molecule imaging and more high impact Integrative Biology research

The research highlighted by this week’s front cover artwork comes from Hexin Chen and Qian Wang et al. at the University of South Carolina, USA.  This cover article was featured on the blog last week and will now be free to access for the next 6 weeks*. The team are focused on how 3D culture conditions affects cancer cell behaviour. In this cover article, they study the effect of fibrous scaffolds, discovering that the epithelial-to-mesenchymal transition of the MCF-7 cells is enhanced.

Expansion of breast cancer stem cells with fibrous scaffolds
Sheng Feng, Xinrui Duan, Pang-Kuo Lo, Shou Liu, Xinfeng Liu, Hexin Chen and Qian Wang
DOI: 10.1039/C3IB20255K


Issue 5 includes a review article from Editorial Board member Philip Day at University of Manchester, UK, and Ehsan Ghayoor Karimiani, Mashhad University of Medical Sciences, Iran. They review the impact of quantitative single cell measurements on future therapies for haematological malignancies. This article was also the subject of an interesting April blog post, which you could read now for a brief idea of what this interesting review covers.

Personalised treatment of haematological malignancies through systems medicine based on single molecules in single cells
Ehsan Ghayoor Karimiani and Philip Day
DOI: 10.1039/C3IB20258E    


You will also find a tutorial review on single molecule imaging (featured on the blog here) and of course highly significant primary research and two Technical Innovations in this month’s issue of Integrative Biology:

Single-molecule imaging in vivo: the dancing building blocks of the cell
Miguel Coelho, Nicola Maghelli and Iva M. Tolić-Nørrelykke 
DOI: 10.1039/C3IB40018B

A model of membrane contraction predicting initiation and completion of bacterial cell division
Claire E. Dow, Alison Rodger, David I. Roper and Hugo A. van den Berg
DOI: 10.1039/C3IB20273A

Three-dimensional photolithographic micropatterning: a novel tool to probe the complexities of cell migration
Joseph C. Hoffmann and Jennifer L. West
DOI: 10.1039/C3IB20280A

*Free access to individuals is provided through an RSC Publishing personal account. Registration is quick, free and simple

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One Response to “Issue 5 now online! 3D cell culture, systems medicine, single-molecule imaging and more high impact Integrative Biology research”

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