The latest issue of Integrative Biology is now online, and is a themed issue guest edited by Mina J. Bissell, Cyrus M. Ghajar and Luke P. Lee, entitled ‘From single cells to biology‘.
The inside front cover features an article by Derek C. Radisky and colleagues at the Mayo Clinic, USA, which demonstrates the use of three-dimensional microenvironments to reveal key features of tumor malignancy in lung cancer cells.
Growth of lung cancer cells in three-dimensional microenvironments reveals key features of tumor malignancy
Magdalena A. Cichon, Vladimir G. Gainullin, Ying Zhang and Derek C. Radisky
The issue also features two other HOT articles – a perspective article from Helen M. Blau and co-workers discussing single cell studies of adult stem cell self-renewal, and a research article from Luke P. Lee, Matthias Peter and colleagues featuring an assay platform for quantitative analysis of single cell chemotaxis.
A single cell bioengineering approach to elucidate mechanisms of adult stem cell self-renewal
Penney M. Gilbert, Stephane Corbel, Regis Doyonnas, Karen Havenstrite, Klas E. G. Magnusson and Helen M. Blau
Quantitative and dynamic assay of single cell chemotaxis
Sung Sik Lee, Peter Horvath, Serge Pelet, Björn Hegemann, Luke P. Lee and Matthias Peter