Author Archive

Black tea: chemical analysis and stability

Graphical abstract of C2FO30093ATea is one of the most popular drinks worldwide, and it’s nutritional value is comes mainly from the tea polyphenols which are reported to possess a broad spectrum of biological activities.  These include reduction of various cancers, inhibition of inflammation, and protective effects against diabetes and obesity.

In this review article researchers from Rutgers University (USA), National Chiayi University and National Kaohsiung Marine university (Taiwan) review the chemical analysis and stability of black tea.  Accurate analysis of the components of black tea is important for quality control, but also to identify the important biologically active molecules within it and their efficacy in animal and human studies.  Based on these finding, new and improved tea products can be produced.  This review article summarizes the major components of black tea before looking at the methods of analyzing these compounds and their stability.

Read the full article for free:

Black tea: chemical analysis and stability, Shiming Li, Chih-Yu Lo, Min-Hsiung Pan, Ching-Shu Lai and Chi-Tang Ho, Food Funct., 2013, 4, 10-18

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Webinar: The power of modern HPTLC

Chemistry World Webinars logo

Join Chemistry World and Advion for a webcast on the latest developments in HPTLC technology.

WHAT: Professor Morlock from the University of Giessen, Germany, will give an overview of current HPTLC methodology, explore some examples of HPTLC-MS coupling and review other current hyphenations in HPTLC. By the end of this free webinar, you will be able to:
– Recognise the power of modern HPTLC
– Learn about current hyphenations in HPTLC
– Understand the principle of elution-based HPTLC-MS
– Recognise how HPTLC hyphenations efficiently support analyses

WHEN: Wednesday, 20 March 2013 – 15:00 GMT

HOW: Click here to register (free)

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Food & Function issue 3 – now online!

Food & Function, issue 3, 2013, front coverThe latest issue of Food & Function is now available to read online.

In this month’s issue, the front cover highlights research by Zhaoping Li and colleagues from the University of California, Los Angeles, USA who report the beneficial health effects of adding Hass avocado to hamburgers.  The team found that ingesting the avocado with the hamburger patty led to beneficial anti-inflammatory and vascular health effects.  Participants in the study who ate 250 g of beef (without avocado) experienced a significant decrease in vascular reactivity, increase of serum IL-6 and NFκB activation in PBMCs – symptoms which could be reduced by adding avocado to meat sandwiches.

Read the full article for free for 6 weeks:

Hass avocado modulates postprandial vascular reactivity and postprandial inflammatory responses to a hamburger meal in healthy volunteers, Zhaoping Li, Angela Wong, Susanne M. Henning, Yanjun Zhang, Alexis Jones, Alona Zerlin, Gail Thames, Susan Bowerman, Chi-Hong Tseng and David Heber, Food Funct., 2013, 4, 384-391

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Spice up your life

Picture of spices on a market stall - © ShutterstockAs well as adding great flavours to the foods we eat and enhancing the sensory qualities of our meals, spices also provide us with many health benefits.  These include radioprotective effects as well as helping us to fight against, and prevent, diseases such as alcohol-induced hepatotoxicity, cancers and diseases of the bowel.

Read about some of the latest research in this area from selection of articles published in Food & Function below – all free to access until the 19th March 2013!

Dietary spices as beneficial modulators of lipid profile in conditions of metabolic disorders and diseases, Krishnapura Srinivasan, Food Funct., 2013, DOI: 10.1039/C2FO30249G

Curcumin, an active component of turmeric in the prevention and treatment of ulcerative colitis: preclinical and clinical observations, Manjeshwar Shrinath Baliga, Nandhini Joseph, Marikunte V. Venkataranganna, Arpit Saxena, Venkatesh Ponemone and Raja Fayad, Food Funct., 2012, 3, 1109-1117

Radioprotective effects of Zingiber officinale Roscoe (Ginger): past, present and future, Manjeshwar Shrinath Baliga, Raghavendra Haniadka, Manisha Maria Pereira, Karadka Ramdas Thilakchand, Suresh Rao and Rajesh Arora, Food Funct., 2012, 3, 714-723

Dietary agents in the prevention of alcohol-induced hepatotoxicty: preclinical observations, Arnadi Ramachandrayya Shivashankara, Aysha Azmidah, Raghavendra Haniadka, Manoj Ponadka Rai, Rajesh Arora and Manjeshwar Shrinath Baliga, Food Funct., 2012, 3, 101-109

Inhibitory effects of 1,3-bis-(2-substituted-phenyl)-propane-1,3-dione, β-diketone structural analogues of curcumin, on chemical-induced tumor promotion and inflammation in mouse skin, Chuan-Chuan Lin, Yue Liu, Chi-Tang Ho and Mou-Tuan Huang, Food Funct., 2011, 2, 78-83

Stay up to date with the latest developments from Food & Function by signing up for free table of contents alerts

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Regulation of cancer cell proliferation

Cancer cells © ShutterstockResearch in recent years has shown that some of the foods and drinks we ingest on a daily basis can inhibit or regulate the proliferation of cancer cells, thus helping to prevent the spread of the disease further.  Here are a selection of articles from Food & Function showing some of the latest research in this area, including insights into how these foods regulate cell proliferation.

These articles are free to access!

Antiproliferative activities of tea and herbal infusions, Fang Li, Sha Li, Hua-Bin Li, Gui-Fang Deng, Wen-Hua Ling and Xiang-Rong Xu, Food Funct., 2013, DOI: 10.1039/C2FO30252G*

Hypericum androsaemum water extract inhibits proliferation in human colorectal cancer cells through effects on MAP kinases and PI3K/Akt pathway, Cristina P. R. Xavier, Cristovao F. Lima, Manuel Fernandes-Ferreira and Cristina Pereira-Wilson, Food Funct., 2012, 3, 844-852*

Antiproliferative mechanisms of quercetin in rat activated hepatic stellate cells, Li-chen Wu, In-wei Lu, Chi-Fu Chung, Hsing-Yu Wu and Yi-Ting Liu, Food Funct., 2011, 2, 204-212

Multistage carcinogenesis process as molecular targets in cancer chemoprevention by epicatechin-3-gallate, Min-Hsiung Pan, Yi-Siou Chiou, Yin-Jen Wang, Chi-Tang Ho and Jen-Kun Lin, Food Funct., 2011, 2, 101-110

Stay up to date with the latest developments from Food & Function by signing up for free table of contents alerts.

*Articles are free to access until the 21st February 2013.

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New model to predict dietary energy intake

Recently there has been considerable debate on what is the most appropriate and accurate method to predict the available energy to humans from food, particularly relating to factorial models vs.empirical models.  Molecule of adenosine-5'-triphosphate (ATP) - © ShutterstockAn alternative approach would be to calculate the physiologically available energy of food at the cellular level (ATP, or adenosine-5′-triphosphate), based on stoichiometric relationships and predictive uptakes of nutrients from the digestive tract. 

In this work, Leah Coles and colleagues from the Baker IDI Heart & Diabetes Institute (Australia) and the Riddet Institute, Massey University (New Zealand) have developed just such a model. The model takes ‘energetic costs’ into account when considering the ATP yield, such as the energetic cost of digesting, absorbing and transporting nutrients in the body. The model is potentially a valuable tool for the development of certain food products which need to provide accurate quantities of energy intake, such as specialised weight-loss products. 

Read the full article for free until the 7th Feburary 2013!

A model to predict the ATP equivalents of macronutrients absorbed from food, Leah Coles,  Shane Rutherfurd and Paul Moughan, Food Funct., 2013, DOI: 10.1039/C2FO30239J

You can keep up to date with the latest developments from Food & Function by signing up for free table of contents alerts and monthly e-newsletters.

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Chemopreventive properties of Grecian dried grapes

Colorectal cancer is one of the major causes of cancer-related mortalities in humans across the world.  The disease is one influenced by several factors including diet, environment and smoking.  Previous studies into the effects of diet on this disease have indicated an inverse relationship between consumption of fruits and vegetables and the risk of developing colon cancer. 

Graphical abstract for C2FO30259DIn this study, Andriana Kaliora and colleagues from Harokopio University and Corinthian Raisins Cooperative SKOS A.S.E., Greece, have looked at the impact of the total phenolic content from raisins and sultanas on colon cancer cells.  Extracts from both raisins and sultanas showed DPPH scavenging activity in a dose-dependent manner, and both suppressed cell proliferation.  Methanol extracts of the sultanas and raisins exhibited anti-radical activity in vitro and cancer preventative efficacy on colon cancer cells, with sultanas having slightly higher activity.

The authors attribute the beneficial properties of the raisins and sultanas from this region to their high phenolic content.

This article is free to access until the 4th February 2013!

Chemopreventive properties of raisins originating from Greece in colon cancer cells, Aggeliki M. Kountouri, Aristea Gioxari, Evangelia Karvela, Andriana C. Kaliora, Michalis Karvelas and Vaios T. Karathanos, Food Funct., 2013, DOI: 10.1039/C2FO30259D

You can keep up to date with the latest developments from Food & Function by signing up for free table of contents alerts and monthly e-newsletters.

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Food & Function issue 1, 2013 now online!

Welcome to the first issue of Food & Function for 2013!  Read the Editorial by Professor Gary Williamson and Sarah Ruthven here.

The front cover of this issue features work by Alan Crozier and colleagues from the University of Glasgow, UK, and Welch Foods Inc., USA. The team investigated the aromatic compounds that result from colonic catabolism of Concord grape juice using an in vitro model of colonic fermentation. After consuming the grape juice substantial quantities of (poly)phenolic compounds reach the large intestine, where they are degraded to bioactive phenolic acids and aromatic compounds, which pass through the circulatory system before being excreted in the urine. The in vivo fate of these catabolites following absorption in the colon was also investigated by GC-MS. It was found that 40% of ingested (poly)phenolic compounds in Concord grape juice pass from the small to the large intestine and contributes to the increased bioavailabilty of the Concord grape polyphenolics.

Read the full article for free!

Colonic catabolism of dietary phenolic and polyphenolic compounds from Concord grape juice, Angelique Stalmach, Christine A. Edwards, Jo Lynne D. Wightman and Alan Crozier, Food Funct., 2012, 4, 52-62

You can keep up to date with the latest developments from Food & Function by signing up for free table of contents alerts and monthly e-newsletters.

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Is organic food more nutritious than non-organic food?

Different fertilisers and farming techniques affect the mineral content of plants in different ways

Different fertilisers and farming techniques affect the mineral content of plants in different ways

Scientists in Denmark have compared how organic and non-organic diets affect dietary mineral uptake in humans, focusing on copper and zinc. They found that there is no difference between the two diets when it comes to uptake and how the minerals are processed in the body.

Copper and zinc are two essential trace elements with unknown availability in organic verses non-organic diets. Alicja Budek Mark and colleagues at the University of Denmark investigated the content of these elements in non-organic versus all-organic diets fed to 20 men over 12 days. And Mark’s team assessed the in vivo absorption of zinc and copper by analysing faecal samples taken from the men during days 8–12.

Read the full article in Chemistry World.

Tweet: RT @ChemistryWorld There may be reasons to eat organic food, but improved mineral uptake isn’t one of them http://rsc.li/Zf6I6z 

Link to journal article
Consumption of organic diets does not affect intake and absorption of zinc and copper in men – evidence from two cross-over trials
Alicja Budek Mark, Emese Kápolna, Kristian H. Laursen, Ulrich Halekoh, Søren K. Rasmussen, Søren Husted, Erik H. Larsen and Susanne Bügel
Food Funct., 2013, Advanced Article
DOI: 10.1039/C2FO30247K

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2nd Oxford Functional Food Conference – Poster prize winner

Caroline Montelius receiving her prize from Professor Michael Eskin

Caroline Montelius receiving her prize from Professor Michael Eskin

The 2nd Oxford Function Food Conference was held at The Oxford Hotel from the 13th-14th November 2012.  This year’s conference focused on functional foods and the role they play in helping to tackle obesity, diabetes and inflammation, and the 2-day programme included contributions from the UK, Europe, Canada and the US in the form of plenary lectures, symposium sessions and poster sessions.

Food & Function was delighted to be able to sponsor a poster prize for innovation at this year’s conference, which was awarded to Caroline Montelius from Lund University for her poster “Supplementation of thylakoids to a high carbohydrate meal decrease feelings of hunger, elevate CCK and prevent hypoglycaemia in overweight women“.  Congratulations Caroline!

Missed out on attending the conference? Go to the website for full highlights from the event including photos from the sessions and copies of some of the presentations.

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