Vitamin B12 plays an important role in the metabolism of many organisms, particularly mammals. Since efficient delivery of vitamin B12 into cells has potential applications in medical therapies, Zelder et al. are sure to inspire wider interest in the design, chemistry and biology of backbone modified B12 derivatives with this hot Perspective.
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Peptide B12: emerging trends at the interface of inorganic chemistry, chemical biology and medicine
Felix Zelder, Kai Zhou and Marjorie Sonnay
Dalton Trans., 2013