Declan Gaynor and Darren Griffith discuss how medicinal inorganic chemistry is currently flourishing in this Dalton Transactions Perspective. Understanding the role of metals in biological systems is very important for drug design; the predictability and control of inorganic complexes make fine-tuning the properties of drugs incorporating such complexes a real possibility. Metal-based compounds are already routinely administered on a regular basis and this Perspective encourages chemists to further investigate inorganic therapeutic and diagnostic medicine by looking at previous successes, e.g. MRI contrast agents, then moving onto current challenges such as antibacterial compounds for tackling hospital acquired infections.
To find out more, you can download the Perspective now – which is free to access for 4 weeks!
The prevalence of metal-based drugs as therapeutic or diagnostic agents: beyond platinum
Declan Gaynor and Darren M. Griffith
Dalton Trans., 2012
DOI: 10.1039/C2DT31601C, Perspective
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