This HOT paper by Ian Dance, from the University of New South Wales, reports on the mechanism of proton relay in nitrogenase enzymes. The proton relay from the protein surface to a key sulfur atom of the FeMo-cofactor plays a core role in many of nitrogenase’s chemical mechanisms.
To read more about the detailed analysis of this mechanism you can download the full paper below…
The controlled relay of multiple protons required at the active site of nitrogenase
Dalton Trans., 2012
Here are some of Ian Dance’s other recent Dalton Transactions publications:
Ramifications of C-centering rather than N-centering of the active site FeMo-co of the enzyme nitrogenase
Dalton Trans., 2012,41, 4859-4865
DOI: 10.1039/C2DT00049K, Paper
Calculated vibrational frequencies for FeMo-co, the active site of nitrogenase, bearing hydrogen atoms and carbon monoxide
Dalton Trans., 2011,40, 6480-6489
DOI: 10.1039/C1DT10505A, Paper
How does vanadium nitrogenase reduce CO to hydrocarbons?
Dalton Trans., 2011,40, 5516-5527
DOI: 10.1039/C1DT10240K, Paper
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