Challenge and progress: palladium-catalyzed sp3 C–H activation

In the last several decades, direct sp2 C–H activation of (hetero)arenes as well as some olefins has been extensively investigated and found impressive applications in organic synthesis, which has been the subject of many papers and reviews. In comparison, much less research has been devoted to the activation of more ‘‘inert’’ sp3 C–H bonds of alkyl groups.

In this Catalysis Science & Technology Perspective, Zhang-Jie Shi and colleagues tell us about the progress in the field using Palladium catalysis. Get quickly up to date in this area by reading their Perspective Article:

 

Challenge and progress: palladium-catalyzed sp3 C–H activation
Hu Li, Bi-Jie Li and Zhang-Jie Shi
Catal. Sci. Technol., 2011, DOI: 10.1039/C0CY00076K, Perspective

  

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