Scientists in Argentina, Germany and Austria have made electrodes by combining enzymes and mediators using concanavalin A (Con A) as a binding reagent.
This introduces a new and flexible way to assemble functional multi-enzyme layers and architectures on an electrode surface, forming highly versatile enzymatic electrodes.
Using redox-active Con A as a biorecognisable platform enables spontaneous assembly. Electrical wiring of multiple enzyme layers onto electrodes is an unexplored research topic and this is the first study on this.
The research could be used to create functional soft biointerfaces displaying specific building blocks at controlled sites into 3D interfacial nanoarchitectures.
Read the PCCP article today hot off the press:
Recognition-Driven Layer-by-Layer Construction of Multiprotein Assemblies on Surfaces:
Biomolecular Toolkit for Building Up Chemoresponsive Bioelectrochemical Interfaces
Diego Pallarola et al.
Phys. Chem. Chem. Phys., 2012, DOI: 10.1039/c2cp41225j
PCCP publishes great research in the fields of biophysical chemistry and biophysics – take a look at the PCCP Biophysics & Biophysical Chemistry themed issue series.