Caffeine-fuelled fix for runaway eye treatment

Written by Jenifer Mizen for Chemistry World

Eye infection treatments that resist being blinked away could be formulated by cocrystallising an antibiotic with caffeine.

Cocrystallising sulfacetamide (left) with caffeine (right) makes it less soluble

Sulfacetamide (SACT) is often lost on blinking and in tears when applied as a treatment for conjunctivitis and other ocular ailments. This leads to the inconvenience and complications of applying larger and more frequent doses of SACT….’

Interested? Read the full article at Chemistry World.

Please click on the below title to access the original article.

Modulating the solubility of Sulfacetamide by means of cocrystals
Ashwini Nangia, Rajesh Goud and Ronaq Ali Khan  
CrystEngComm, 2014, Accepted Manuscript
DOI: 10.1039/C4CE00103F, Paper

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