This Highlight presents an overview of hydrogel-based double-diffusion systems to study biomineralization. The authors describe two types of diffusion systems: static and dynamic. They evaluated four such systems to design an optimized system taking into account the type of hydrogel, the boundary conditions and design strategy.
Gels represent a good model to study and understand biomineralization because the mineral deposition that occurs in many mineralization processes in vivo takes place in gelling environments; however, they are not often used due to their complexity and poor knowledge of ionic diffusion.
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Rediscovering hydrogel-based double-diffusion systems for studying biomineralization
Jason R. Dorvee , Adele L. Boskey and Lara A. Estroff
CrystEngComm, 2012, Advance Article
Other articles by Lara A. Estroff and co-workers which may also be of interest are:
Gel incorporation inside of organic single crystals grown in agarose hydrogels
Hanying Li, Yuzo Fujiki, Kazuki Sada and Lara A. Estroff
CrystEngComm, 2011, 13, 1060-1062
DOI: 10.1039/C0CE00118J, Communication
Porous calcite single crystals grown from a hydrogel medium
Hanying Li and Lara A. Estroff
CrystEngComm, 2007, 9, 1153-1155
DOI: 10.1039/B709068D, Communication
From themed issue: CrystEngComm focuses on biomineralisation