The introduction of chirality into Metal Organic Frameworks (MOFs) produces the possibility of them being used as solid supports for chiral chromatography. This chirality can be introduced through the use of pillararene struts where the pendant functional groups can be controlled to alter the overall properties. However, the incorporation of planar chirality into homochiral MOFs is a relatively unexplored phenomenon.
Homochiral MOFs which contain enantiopure active domains
In this Communication Fraser Stoddart, from Northwestern University, and his team report the production of homochiral MOFs which contain enantiopure pillararene active domains. This required the development of an efficient route to the large-scale production of racemic pillararene derivatives. However, to discover the secret you will have to read the ChemComm article – access is free* for a limited time only!
To read the details, check out the Chem Comm article in full:
Nathan L. Strutt, Huacheng Zhang and J. Fraser Stoddart
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